Heather J. Landau, MD
Bone Marrow Transplant Specialist & Cellular Therapist
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Areas of Expertise
My Specialties
- Hematologic Malignancies
- Plasma Cell Dyscrasias, Including Multiple Myeloma, Light Chain Amyloidosis, and Plasmacytomas
About Me
- Director, Amyloidosis Program
I am a board-certified oncologist and hematologist, and work as part of a multidisciplinary team caring for patients with hematologic disorders. I have a special interest and expertise in treating patients with disorders that arise in white blood cells called plasma cells, including multiple myeloma and light chain (AL) amyloidosis.
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My research focuses on new treatment approaches for plasma cell disorders. Along with colleagues here, I am testing targeted therapies, immunomodulatory agents, and stem cell transplantation to arrive at more-effective and less-toxic regimens for these diseases.
Very effective novel agents have recently become available for plasma cell disorders, but it is not clear if these are more effective than stem cell transplantation for patients early in the course of their disease. To help answer that question, I am co-leading a study comparing the effectiveness of an immunomodulatory agent (lenalidomide) with that of high-dose therapy and stem cell transplantation. I am also leading a trial to determine the most effective post-stem cell transplant therapy. As the principal investigator of an ongoing trial using a risk-adapted approach to stem cell transplant followed by novel agents in AL amyloidosis, I have had the opportunity to present exciting results demonstrating significant activity and low toxicity with this approach.
For patients whose plasma cell disorder has relapsed, I am investigating novel agents alone and in combinations. Some patients with multiple myeloma and plasma cell disorders do poorly despite treatment. I am collaborating with colleagues here in efforts to develop safer and more-effective donor-derived (allogeneic) hematopoietic stem cell transplantation options using T-cell-depleted grafts, a strategy pioneered at Memorial Sloan Kettering. In order to improve accessibility to treatment and the quality of life of our patients, I am also helping to develop outpatient transplant strategies using state-of-the-art technology (Tele-Health monitoring).
I have also enjoyed mentoring students from the college level through the post-graduate level.
A bone marrow transplant specialist is a doctor with special training in bone marrow transplants.
A cellular therapy specialist is a doctor with special training in using cell therapies to treat health conditions such as cancer. Therapies can include chimeric antigen receptor (CAR) T cell therapy.
My Specialties
- Hematologic Malignancies
- Plasma Cell Dyscrasias, Including Multiple Myeloma, Light Chain Amyloidosis, and Plasmacytomas
Education
- MD, Upstate Medical University
Residencies
- Internal Medicine - University of Colorado Health Sciences Center
Fellowships
- Hematology/Oncology - Memorial Sloan Kettering Cancer Center
Board Certifications
- Internal Medicine
- Medical Oncology
- Hematology
Insurance Information
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Contact and Location
Dr. Landau sees patients at one location.
Looking to see a doctor at a different location? See all MSK locations.
Colleagues
Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.
Clinical Trials
- Clinical Trials Investigated by Dr. Landau
- A Phase 1b Study of NXC-201 Cellular Therapy for People With AL Amyloidosis
- A Phase 2 Study of Daratumumab Plus Bortezomib, Cyclophosphamide, and Dexamethasone in People With Amyloid Light Chain Amyloidosis
- Pilot Study of Homebound Stem Cell Transplantation for Patients with Multiple Myeloma
- Clinical Trials Co-Investigated by Dr. Landau
- A Phase II Study of Iberdomide in People with Multiple Myeloma Who Have Had an Autologous Stem Cell Transplant
Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.
You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.
Search clinical trialsResearch and Publications
Visit PubMed for a full listing of Dr. Landau’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.
See all on PubMedPatient Reviews
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Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Heather J. Landau discloses the following relationships and financial interests:
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AbbVie
Professional Services and Activities -
Alexion Therapeutics
Professional Services and Activities -
Immix Biopharma, Inc.
Professional Services and Activities
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Legend Biotech USA Inc.
Professional Services and Activities -
Prothena Corporation plc
Professional Services and Activities
If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.
The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.
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