Cell Biology Program
The Marilyn Resh Lab
Research
![Marilyn Resh](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/1594/person/marilyn-resh.jpg?h=10d202d3)
The goal of my laboratory’s research is to understand how fatty acylation influences the structure and function of membrane-bound and secreted signaling proteins. Our focus is on the Src family tyrosine protein kinases, Hedgehog and Wnt proteins.
Research Projects
![The Marilyn Resh Lab](https://www.mskcc.org/sites/default/files/node/1594/3x2/group-lab-photo_low-res_2018_1200x800.jpg)
Publications Highlights
People
![Marilyn Resh](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/1594/person/marilyn-resh.jpg?h=10d202d3)
Marilyn Resh, PhD
Member
- Cell biologist Marilyn Resh investigates the regulation of protein function by fatty acylation, and the development of Hedgehog palmitoylation inhibitors to block pancreatic and lung cancer.
- PhD, Harvard University
- AB, Princeton University
- [email protected]
- Email Address
- 212-639-2514
- Office Phone
Members
![Debra Alston](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/106395/3x2/debra-alston.jpg)
![Kalpana Rajanala, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/116917/3x2/rajanala_3x2.jpg)
![Adina Schonbrun](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/160339/3x2/adina_2018_3x2.jpg?h=10d202d3)
- BA, Yeshiva University
![Jing Zhou, Ph.D.](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/151018/3x2/zhou-jing_180427_07_1200x800.jpg)
- 212-717-3317
- Office Fax
- 212-639-2551 or 2552
- Lab Phone
![Marilyn Resh](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/1601/3x2/marilyn-resh.jpg)
![Debra Alston](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/106395/3x2/debra-alston.jpg)
Sr. Administrative Assistant
![James Asciolla](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/106387/3x2/james-asciolla.jpg)
Graduate Student
![Atul Khire, Ph.D.](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/151021/3x2/khire-atul_180427_14_1200x800.jpg)
Postdoctoral Fellow
![Kalpana Rajanala, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/116917/3x2/rajanala_3x2.jpg)
Research Fellow
![Adina Schonbrun](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/160339/3x2/adina_2018_3x2.jpg?h=10d202d3)
Scientific Editor, Periodt Scientific Communications/Plant Editions - Freelance
![Jing Zhou, Ph.D.](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/151018/3x2/zhou-jing_180427_07_1200x800.jpg)
Postdoctoral Fellow
![Raisa Louft-Nisenbaum](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/1600/3x2/raisa-louft-nisenbaum.jpg)
Research Technician
![Marilyn Resh](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/1601/3x2/marilyn-resh.jpg)
Member
![Rita Curti](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/106391/3x2/rita-curti.jpg)
![Brittany Haugen](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18454/3x2/brittany-haugen_0.jpg)
- BS, Florida Institute of Technology
![Armine Matevossian](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/6416/image/armine-matevossian.jpg?h=10d202d3)
- University of Massachusetts Amherst
- 212-639-2551
- Office Phone
Lab Alumni
![Rita Curti](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/106391/3x2/rita-curti.jpg)
Student Research Assistant
![Brittany Haugen](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18454/3x2/brittany-haugen_0.jpg)
Graduate Student
![Armine Matevossian](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/6416/image/armine-matevossian.jpg?h=10d202d3)
Principal Scientist at EMD Sero Inc., Cambridge, MA
Lab Affiliations
Achievements
- Excellence in Teaching and Mentoring Award, Weill Cornell Graduate School (2009)
- Established Scientist, American Heart Association (1994-1999)
- Pew Scholar in the Biomedical Sciences, Pew Charitable Trusts (1987-1991)
- Discovery of the ""two-signal hypothesis"" for binding of myristoylated proteins to membranes
- Discovery of a myristoyl switch mechanism for membrane binding of HIV-1 Gag
Read more
- First to establish Hedgehog acyltransferase as a bona fide palmitoyl acyltransferase for Hedgehog proteins
- Discovery of the first-in-class hedgehog palmitoylation inhibitor
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs
Get in Touch
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Lab Head Email
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Office Phone
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Office Fax
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Lab Phone
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Lab Fax