Gustav Cederquist

Email

I am interested to explore developmental mechanisms that generate temporal and spatial boundaries within the human cerebral cortex. I am also interested to understand how these processes might go awry in brain disease. As an undergraduate, I worked with Dr. Jeffrey Macklis to investigate genetic controls that diversify projection neuron subtype identity within precise regions of the mammalian cortex. I then worked with Dr. Elizabeth Engle to understand the genetic and molecular basis of human disorders of axon guidance.

Publications

Cederquist GY, Azim E, Shnider SJ, Padmanabhan H, Macklis JD. (2013). LMO4 establishes rostral motor cortex projection neuron diversity. Journal of Neuroscience, 33(15):6321-6332.

Cederquist GY, Luchniak A, Tischfield MA, Peeva M, Menezes M, Chan W, Andrews C, Chew S, Jamieson RV, Flaherty M, Gomes L, Grant PE, Gupta ML, Engle EC. (2012). An inherited TUBB2B mutation alters kinesin binding and causes polymicrogyria, CFEOM, and axon dysinnervation. Human Molecular Genetics, 21(26):5484-5499.

Tischfield MA, Cederquist GY, Gupta ML Jr., Engle EC. (2011). Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations. Current Opinions in Genetics & Development. 21(3):286-94.

Azim E, Shnider S, Cederquist GY, Sohur US, Macklis JD. (2009). Lmo4 and Clim1 progressively delineate cortical projection neuron subtypes during development. Cerebral Cortex, 19 Suppl 1, i62-69.