![](https://www.mskcc.org/sites/default/files/node/142204/main_image_large/tammelalab_hero_image_101320-1920x384.jpg)
Cancer Biology & Genetics Program
The Tuomas Tammela Lab
Research
![Dr. Tuomas Tammela](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/142204/person/tammela_181018_05_1200x800.jpg?h=cad4df64)
The Tammela lab is interested in understanding the remarkable phenotypic heterogeneity of cancer cells within tumors. We approach this question using a combination of sophisticated genetically engineered mouse models, single-cell approaches, tracing and ablation of distinct tumor cell lineages, CRISPR-mediated gene regulation, and advanced imaging techniques. We utilize the exceptional resources developed by our MSK collaborators, such as organoids and xenografts, for the translation of our findings into new treatments for human cancer. Our goal is to discover pathways that drive distinct cellular phenotypes and to develop new therapeutic concepts aimed at reducing cellular heterogeneity in tumors.
Research Projects
![Tuomas Tammela Lab](https://www.mskcc.org/sites/default/files/node/142204/images/tammela_210723_008-1200x800_0.jpg)
Featured News
![Tuomas Tammela](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/171280/3x2/181101_day4_04_tammela_lab_0052_1200x800.jpg)
![scientific image of mouse lung cancer cells](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/289356/main_image/mouse_resistantcells-yellow-_12x8.jpg)
![Section of a lung cancer tumor in mice](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/200887/main_image/tma18-r2-pdx-40x-itga2_pck_dapi_cr3-1200x800.jpg)
Publications Highlights
People
![Dr. Tuomas Tammela](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/142204/person/tammela_181018_05_1200x800.jpg?h=cad4df64)
Tuomas Tammela, MD, PhD
Associate Member, Cancer Biology & Genetics Program, MSKCC
- Cancer biologist Tuomas Tammela investigates cellular heterogeneity in lung and pancreatic cancers.
- Massachusetts Institute of Technology: Postdoctoral Fellowship
- University of Helsinki, Finland: MD, PhD
- 646-888-2048
- Office Phone
Members
![Photo of Klavdija Bastl](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/251661/main_image/bastl-klavdija-220815-005_1200x1200_0.jpg?h=cd2a7045)
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/279946/main_image/professional_lab_headshot__720.jpg?h=34e43602)
![Xueqian Zhuang, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/157471/3x2/zhuang-xueqian_180509_06_1200x800.jpg?h=38fd8c93)
![Photo of Heather Alcorn](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/251646/main_image/alcorn_heather_headshot_220815-020_rt_1200x800.jpg?h=65f4d89c)
Lab Manager
![Photo of Klavdija Bastl](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/251661/main_image/bastl-klavdija-220815-005_1200x1200_0.jpg?h=cd2a7045)
GSK Graduate Student; Harold Varmus Scholar in Cancer Biology; Boehringer Ingelheim Fond PhD Fellow
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/279946/main_image/professional_lab_headshot__720.jpg?h=34e43602)
Research Technician
![Jason Chan, MD, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/157474/3x2/chan-jason_180508_06_1200x800.jpg?h=8122e98c)
Clinical Instructor
Postdoctoral Fellow
![Zhuxuan Li](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/208741/main_image/li-zhuxuan_200909_10-1200x800.jpg?h=62ccfd8a)
PhD Student
Research Technician
![Photo of Chun-Hao Pan](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/251651/main_image/pan-chun-hao-220815-005_rt_1200x800_0.jpg?h=36ee6d33)
Postdoctoral Fellow
MSK Bridge Scholar
![Jonathan Rub](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/231253/main_image/rub-jonathan_210723_008-1200x800.jpg?h=1576046a)
PhD Student
Administrative Assistant
![Photo of Dr. Anupriya Singhal](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/251656/main_image/singhal-anupriya_210812_07_rt_1200x800.jpg?h=13e9491a)
Clinical Fellow
![Hannah Styers, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/231256/main_image/styers-hannah-230315-003_rt_1200x800.jpg)
Research Technician
![Xueqian Zhuang, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/157471/3x2/zhuang-xueqian_180509_06_1200x800.jpg?h=38fd8c93)
Postdoctoral Fellow; NYSTEM Training Award at the Center for Stem Cell Biology (CSCB)
![Alexander Ferrena](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/166978/3x2/ferrena-alexander_181115_16_1200x800.jpg?h=13d017d5)
![Olivera Grbovic-Huezo](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150637/main_image/grbovic-huezo-olivera_210723_014-1200x800.jpg?h=d84cb6af)
![Matilda Holm](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/231250/main_image/holm-matilda_210723_006-1200x800.jpg?h=1576046a)
![Anna Hudson](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/165829/3x2/hudson_181018_01_1200x800.jpg?h=e2380de3)
![Simon Joost, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/208732/main_image/joost-simon_200909_10-1200x800.jpg?h=4af3535f)
![Ken Pitter, MD, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/165820/3x2/pitter_181018_05_1200x800.jpg?h=03622fc9)
![Stefan Torborg](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/165826/3x2/torborg_181018_02_1200x800.jpg?h=563f6d91)
Lab Alumni
![Melissa Blum, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/208738/main_image/blum-melissa_200909_04-1200x800.jpg?h=4af3535f)
M.D. Student, Icahn School of Medicine at Mount Sinai
![Photo of Selena Ding](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/251671/main_image/ding-selena-220815-012_rt_1200x800.jpg?h=0f4b6048)
MD/PhD Student, Icahn School of Medicine at Mount Sinai
![Alexander Ferrena](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/166978/3x2/ferrena-alexander_181115_16_1200x800.jpg?h=13d017d5)
Ph.D. Student, Computational Biology Program, Albert Einstein College of Medicine
![Olivera Grbovic-Huezo](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150637/main_image/grbovic-huezo-olivera_210723_014-1200x800.jpg?h=d84cb6af)
Senior Principal Scientist, Clinical Biomarker Development at Loxo Oncology/Lilly
![Photo of Mikel Gregory](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/251666/main_image/gregory-mikel-220815-021_rt_1200x800_0.jpg?h=6b3ccd88)
BRIDGE Program Post-Baccalaureate trainee
![Griffin Hartmann, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150640/3x2/hartmann-griffien_180509_03_1200x800.jpg?h=353b00d3)
Ph.D. Student, Stanford University
![Matilda Holm](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/231250/main_image/holm-matilda_210723_006-1200x800.jpg?h=1576046a)
Postdoctoral Fellow, Karolinska Institute, Sweden
![Anna Hudson](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/165829/3x2/hudson_181018_01_1200x800.jpg?h=e2380de3)
M.D./Ph.D. Student, University of Miami
![Emily B. Johnson, MPH](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150643/3x2/johnson-emily_180509_11_1200x800.jpg?h=61909beb)
Clinical Research Project Coordinator, MSKCC Pediatrics
![Simon Joost, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/208732/main_image/joost-simon_200909_10-1200x800.jpg?h=4af3535f)
Postdoctoral Researcher
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/279936/main_image/headshot.jpg?h=a6946897)
Administrative Assistant
![Ken Pitter, MD, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/165820/3x2/pitter_181018_05_1200x800.jpg?h=03622fc9)
Assistant Professor, Department of Radiation Oncology, OSUCCC, Columbus, Ohio
![Carleigh Sussman, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/208744/main_image/sussman-carleigh_200909_02-1200x800.jpg?h=80a599a2)
Research Associate, RenBio
![Stefan Torborg](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/165826/3x2/torborg_181018_02_1200x800.jpg?h=563f6d91)
MD-PhD Student; Kirschstein National Research Service Award (F30) Fellow
![Katherine Wu, BS Senior Research Technician](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/145804/3x2/wu_170922_09_3x2.jpg?h=538e9556)
M.D./Ph.D. Student, New York University
![Yan Yan](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/165823/3x2/yan_181018_05_1200x800.jpg?h=f8bb017d)
Assistant Professor, Huazhong Agricultural University
Lab Affiliations
- Cancer Biology & Genetics Program
- Fiona and Stanley Druckenmiller Center for Lung Cancer Research
- Center for Stem Cell Biology
- David M. Rubenstein Center for Pancreatic Cancer Research
- PhD Programs in Computational Biology & Medicine
- MD/PhD Program
- Gerstner Sloan Kettering Graduate School of Biomedical Sciences
Achievements
- Josie Robertson Investigator (2017-2022)
- The Mark Foundation Emerging Leader Award (2021)
- Rita Allen Foundation Scholar (2020)
- National Cancer Institute R37 MERIT Award (2020)
- American Cancer Society Scholar (2020)
Read more
- V Foundation Scholar (2019)
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs
Career Opportunities
Get in Touch
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Office Phone
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Lab Phone
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Tuomas Tammela discloses the following relationships and financial interests:
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Lime Therapeutics, Inc.
Equity; Professional Services and Activities
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].