Recent News

555 News Items found
Proof of Principle: Tri-Institutional Therapeutics Discovery Institute Drug Candidates “Graduate” to Next Phase of Development
Two projects from a portfolio of 57 that the Tri-I TDI has supported have “graduated” with the demonstration that the compounds under study work in preclinical contexts. These compounds are now ready for the next phase of therapeutic development – a phase intended to lead to investigational new drugs. A third project, which originated at Weill Cornell Medicine, is expected to move forward later this month. These projects are candidates for advancement into Bridge Medicines, Inc., a for-profit company established in 2016 by the three Tri-I TDI academic founders, Takeda, and two investment firms – Bay City Capital and Deerfield Management – designed to take Tri-I TDI projects into readiness for clinical trials over a two- to three-year time frame.
In the Lab
A gray blob marked RAS linked to colorful rods marked ICMT
Deciphering How Membrane Enzymes Work, with a Little Help from Beetles
The atomic structure of an elusive type of membrane protein has finally been solved by scientists at the Sloan Kettering Institute.
In the Lab
Illustration of cells with blue nuclei that have green DNA bits floating in the cytoplasm
Escape Artists: Cancer Cells Mimic Immune Cell Activity to Spread
Researchers have discovered that cancer cells may hijack an immune response to spread from a primary tumor to distant organs.
In the Lab
Three-dimensional reconstruction of the blood vessels in a mouse thymus using light-sheet fluorescent microscopy
New Hope for Repairing a Damaged or Aging Immune System
Scientists have uncovered a molecule that, in mice, can promote the regeneration of the thymus, where T cells develop.
Q&A
MP1104 binding to the kappa opioid receptor
Building a Safer Opioid: MSK Research Seeks to Develop New Ways to Relieve Pain
Science could lead to a new type of opioid drug that blocks pain but has a lower potential for addiction or abuse.
Feature
A barred Plymouth Rock hen
How a Chicken Helped Solve the Mystery of Cancer
When this feathered patient found her way into a New York laboratory in 1909, she changed the course of cancer science.
In the News
Gears with 2016 and 2017
Year in Review: The Science and Technology that Shaped Cancer Care in 2017
As 2017 draws to a close, take a look back at the scientific discoveries that deepened our understanding of cancer in the past year.
In the Lab
Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh
When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis
MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.
In the Lab
A microscopic view of genetically engineered mouse tumor and a human FL-HCC tumor
With Help of CRISPR, Scientists Unravel the Cause of a Rare Liver Cancer
A team led by MSK molecular biologist Scott Lowe is making progress against fibrolamellar hepatocellular carcinoma.
Science Byte
Prostate cancer cells, colored red in scanning electron micrograph (SEM).
PSMA: A New Target for Prostate Cancer Treatment
Researchers have discovered how a high level of the protein PSMA in cells helps fuel prostate cancer.