A Phase III Study Comparing Two Surgery Methods to Treat Cancer in the Lung in Patients with Bone Cancer

Full Title

Purpose

The purpose of this study is to compare two different approaches to surgery for children and adults with osteosarcoma (bone cancer) that has spread (metastasized) to the lungs. Participants will be randomly assigned to one of two techniques:

• Open thoracic surgery, which is performed through a single larger incision between the ribs to open up the chest and remove the cancer from the lungs.
• Video-assisted thoracoscopic surgery (VATS), where the surgeon makes several small incisions in the chest and uses a small camera to help guide removal of the cancer.

Who Can Join

To be eligible for this study, patients must meet several requirements, including:

• Participants must have osteosarcoma that has spread to the lungs when newly diagnosed or at first recurrence of the disease.
• There may be no more than 4 lung nodules per lung and no other sites of tumor growth.
• The lung nodules must be determined by one of our participating surgeons to be appropriate for surgical removal using either approach.
• This study is for people under age 50.

Contact

For more information about this study and to inquire about eligibility, please contact 1-833-MSK-KIDS.