A Study of Early Cancer Detection in People at High Risk of Developing Pancreatic Cancer

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Full Title

Hyperpolarized C Pyruvate Magnetic Resonance Imaging, and Blood-Based Biomarkers for Early Detection of Pancreatic Adenocarcinoma in Patients with Intraductal Papillary Mucinous Neoplasms

Purpose

Researchers in this study are assessing a combination of imaging and blood tests to find pancreatic cancer early. The people in this study have an increased risk of this cancer due to pancreatic cysts. They are planning to have surgery to remove the cysts and check them for cancer. It is hoped that the imaging and blood tests can detect pancreatic cancer early so people can avoid surgery.

If you join this study, you will have tests to look for tumor DNA in your blood. You will also have a special type of magnetic resonance imaging (MRI). The MRI is called a hyperpolarized pyruvate (HP) MRI scan. If you wish, you can choose to have just the blood tests without the MRI.

The imaging and blood tests will be done before your surgery. The test results will be compared with the analysis of your pancreatic cysts after your surgery.

Who Can Join

To join this study, there are a few conditions. You must:

  • Have pancreatic cysts that will be removed with surgery.
  • Not have prior evidence of pancreatic cancer.
  • Be age 18 or older.

Contact

For more information or to see if you can join this study, please call Dr. Kevin Soares’ office at 212-639-3195.

Protocol

23-367

Disease Status

Newly Diagnosed

Investigator

ClinicalTrials.gov ID

NCT06305728