Full Title
An Open-label Phase 1 Study to Evaluate the Safety of SGN-35T in Adults with Advanced MalignanciesPurpose
Researchers want to find the best dose of SGN-35T to use in people with lymphoma. The people in this study have Hodgkin or non-Hodgkin lymphoma that came back or keeps growing after treatment.
Many lymphoma cells have a protein called CD30 on their surfaces. This protein plays a role in cancer growth. SGN-35T attaches to CD30 and is designed to destroy cells containing this protein. It is given intravenously (by vein).
Who Can Join
To join this study, there are a few conditions. You must:
- Have lymphoma that came back or keeps growing after treatment and makes CD30.
- Have recovered from the serious side effects of prior anti-cancer therapies before getting SGN-35T.
- Be well enough to walk and take care of yourself. You must be able to do activities such as office work or light housework.
- Be age 18 or older.
Contact
For more information or to see if you can join this study, please call Dr. Alison Moskowitz’s office at 646-608-3726.
Protocol
24-226
Phase
Phase I (phase 1)
Disease Status
Relapsed or Refractory
Investigator
Co-Investigators
Diseases
ClinicalTrials.gov ID
NCT06120504