Full Title
Phase III Trial of Single Fraction Stereotactic Radiosurgery (SRS) Versus Fractionated SRS (FSRS) for Intact Brain Metastases (NRG-BN013) (CIRB)Purpose
The usual treatment for brain metastases (cancer that spread to the brain) is a single treatment of stereotactic radiosurgery (SRS). SRS uses special equipment to position the patient and precisely give a single large dose of radiation to a tumor.
In this study, researchers are comparing the usual treatment to fractionated SRS to treat people with brain metastases. With fractionated SRS, a high dose of radiation is given to the tumor over 3 treatments instead of 1. The 3 treatments are given over a week. Fractionated SRS may work better to treat brain metastases than the usual SRS.
If you join this study, you will be randomly assigned to get either the usual SRS treatment or fractionated SRS.
Who Can Join
To join this study, there are a few conditions. You must:
- Have 1 to 8 intact brain metastases.
- Not have previously received radiation therapy to the brain.
- Be able to walk and do routine activities for more than half the time you are awake.
- Be age 18 or older.
Contact
For more information or to see if you can join this study, please call Dr. Luke Pike’s office at 212-639-8157.