Clinical Updates & Insights

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Our clinical updates provide you with timely information about Memorial Sloan Kettering’s new treatment approaches, key clinical trials, and innovations in detecting and treating many cancers.

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202 Clinical Updates found
Clinical Update
Howard Scher
Profiling Prostate Tumors for MSI May Inform Better Treatment Selection

Profiling prostate cancer tumors for microsatellite instability (MSI) status with targeted next-generation sequencing can identify patients who may respond better to PD-1/PD-L1 agents.
Clinical Update
James Eastham
Prostatectomy and RT Combination Yields Favorable Outcomes in Advanced Prostate Cancer

Men with advanced prostate cancer treated with radical prostatectomy and adjuvant radiotherapy have a lower risk of cancer-specific death and improved overall survival compared to men treated with radiotherapy plus androgen deprivation therapy.
Clinical Update
Elizabeth A. Morris, MD, FACR
The Emerging Role and Value of Abbreviated Breast MRI

Abbreviated breast magnetic resonance imaging is a cost-effective screening tool that should be made available to patients with an average lifetime risk of breast cancer, according to our recent review of protocols.
Clinical Update
Doctor in operating room
Finding a Better Way: Improving the Surgical Paradigm for Ovarian Cancer

Surgical paradigm shifts to achieve complete cytoreduction during primary debulking surgery combined with the use of perioperative epidural anesthesia improve survival outcomes for ovarian cancer patients, our recently published research shows.
Clinical Update
Doctor with patient
Reexamining Surgical Margins in Breast Cancer

Wider negative margins do not improve local control for ductal carcinoma in situ or invasive carcinoma when they are treated with lumpectomy and radiation therapy, our recent literature review shows.
MSK Colorectal doctors
Sidestepping Rectal Cancer Surgery with Total Neoadjuvant Therapy

Total neoadjuvant therapy is a viable treatment strategy for patients with locally advanced rectal cancer and is associated with the potential to sidestep surgical treatment.
stomach illustration
The “Pocket-Creation Method” for Resecting Early-Stage Gastrointestinal Cancers

The “pocket-creation method” is the latest advance in endoscopic submucosal dissection, a technique for the removal of early-stage gastrointestinal cancers, further boosting its superiority over the standard approach of using endoscopic mucosal resection.
Daniel Prince, MD, MPH
Distraction Osteogenesis: Optimal Bone Reconstruction in Pediatric Sarcoma

Although distraction osteogenesis is commonly employed in regular orthopedic surgery, its use in cancer patients is currently limited. But research shows that these durable reconstructions can provide superior opportunities for better long-term limb function and growth in this cohort.
Jodi V. Mones, MD
Managing Chemotherapy-Induced Thrombocytopenia: Romiplostim Research

Our recent research demonstrates that the thrombopoietin receptor agonist romiplostim effectively modifies chemotherapy-induced thrombocytopenia (CIT) in solid tumor patients, allowing a majority to resume chemotherapy
Dr. Paul Chapman
Video: Good News out of ASCO 2018 on Melanoma Treatment Data

Research presented at the 2018 meeting of the American Society of Clinical Oncology showed that the relapse rate is low for melanoma patients treated with immunotherapy, but those who do relapse can respond a second time to immunotherapy. Dr. Chapman discusses the impact. (June 2018)