Clinical Updates & Insights

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Our clinical updates provide you with timely information about Memorial Sloan Kettering’s new treatment approaches, key clinical trials, and innovations in detecting and treating many cancers.

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202 Clinical Updates found
Advanced Ovarian Cancer: Balancing Treatment Risks and Benefits

In contrast with the findings of two international trials, Memorial Sloan Kettering Cancer Center data suggest the standard treatment – primary debulking surgery – may provide better outcomes in select patients when compared to neoadjuvant chemotherapy.
Managing the Inherited Risk of Ovarian Cancer

Risk-reducing salpingo-oophorectomy brings on early menopause and its attendant consequences. Researchers are exploring whether a less drastic surgical strategy can offer a safe and efficacious option.
Trials for Two New Immunotherapies

Immune checkpoint inhibitors and adoptive T cell therapy have shown success in treating several cancers. Now both approaches are in trials for gynecologic cancers, and researchers think even more applications are possible.
A New Era in Axillary Management for Node-Positive Women

After two studies examined the safety of eliminating axillary lymph node dissection (ALND) for some breast cancer patients, Memorial Sloan Kettering Cancer Center further tested their conclusions, confirmed the approach’s applicability and changed clinical practice.
Better Screening, Less Cost

Mammography has shortcomings but the price is reasonable; MRI is more effective but expensive. Two new modalities — contrast-enhanced digital mammography (CEDM) and abbreviated breast MRI (AB-MRI) — may provide the best of both.
Is Low Risk DCIS Really Low Risk?

Research at Memorial Sloan Kettering Cancer Center suggests that what’s usually considered low-risk ductal carcinoma in situ (DCIS) may still present significant risk. Two European trials comparing observation to surgical excision for women with low-risk DCIS are expected to provide important additional data.
Targeting Estrogen Receptors

About a third of patients with metastatic breast cancer don’t respond well to the standard anti-estrogen therapies; to find ways to better treat those patients, Memorial Sloan Kettering Cancer Center is studying three new selective estrogen receptor down-regulators (SERDs) in clinical trials.
A New Method to Improve Bowel Function

Sacral neuromodulation has already helped patients with benignly caused fecal incontinence – can it do the same for rectal cancer patients following sphincter-preserving surgery?
Targeting Peritoneal Cancer Metastases

Two intraperitoneal chemotherapy approaches are being compared for effectiveness and toxicity in Memorial Sloan Kettering Cancer Center’s phase II clinical trial, which continues to enroll cytoreductive cancer surgery patients with isolated peritoneal metastasis.
Sentinel Lymph Node Mapping: Promise and progress

The evolution of the surgical management of regional lymph nodes in patients with melanoma is an extraordinary lesson in the importance of humility and open-mindedness for academic surgeons.