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445 News Items found
In the Lab
Scientist Gabriela Chiosis in her lab
Experimental Drug Targets Misbehaving Proteins in Brain Cancer and Alzheimer’s Disease

Memorial Sloan Kettering researchers are studying how drugs that reverse malfunctioning proteins may treat disease.
In the Lab
Portrait of a live zebrafish with dark patterning around and above the eyes
Uncharted Waters: The Making of a New Cancer Drug

A team of scientists is combining sophisticated chemistry and experiments in zebrafish to develop a new cancer drug that shows early potential against melanoma and metastatic breast cancer.
Chemist Samuel Danishefsky (left) and pharmacologist Ting-Chao Chou have collaborated closely on the study of epothilone drugs.
Finding Cancer Treatments in Nature

From antibiotics to painkillers to cancer drugs, many molecules found in nature have proven to be remedies for human disease. At Memorial Sloan Kettering, a handful of drugs now in clinical trials have been derived from sources ranging from microorganisms to plants to marine creatures. The theory behind the development of drugs from natural products is that these molecules inherently have some kind of biological function, and that function can be enhanced and exploited to develop effective treatments for patients.
Support
Close-up photo of someone walking on the road
Study Shows Patients Are Less Active after Cancer Diagnosis

Learn why some patients are less physically active during and after treatment — plus, some tips from Jun Mao, Chief of the Integrative Medicine Service at MSK.
Finding
Papillary renal cell carcinoma under the microscope
Study Suggests More People with Kidney Cancer Should Be Screened for Hereditary Cancer Genes

Researchers have found that more than 20% of people with a type of cancer called advanced non-clear cell renal cell carcinoma have disease that is driven by inherited cancer mutations.
In the News
an illustration of cancer metastasis
AACR 2019 Research Roundup: Nanosensors for Cancer, New Immunotherapy Targets, a Road Map of Metastasis, and CAR T Fratricide

Read our key takeaways from the second half of the American Association for Cancer Research’s 2019 annual meeting.
Human metastatic melanoma cells in a lymph node. ENPP1, a protein involved in immune evasion, is shown in green.
Taking the STING Out of Cancer: Discovery about How Cancer Cells Evade Immune Defenses Inspires New Treatment Approach

The research identifies a protein called ENPP1 as a potential drug target in the treatment of advanced cancers with chromosome instability.
In the Lab
Pictured: Charles L. Sawyers, William Polkinghorn & Simon Powell
Molecular Studies Explain Effectiveness of Longtime Treatment for Prostate Cancer

Laboratory studies have revealed an explanation for why androgen-deprivation therapy makes radiation therapy more effective in the treatment of high-risk prostate cancer.
Q&A
Memorial Sloan Kettering medical oncologist Dean Bajorin
Immunotherapy Drug Lowers Risk of Bladder Cancer Returning after Surgery

People with bladder cancer may soon have a new treatment option following surgery.
Internist Francesca Gany is seen leaning on a taxicab and smiling. She leads the MSK Immigrant Health & Cancer Disparities Service, which this year marks its tenth anniversary
Do the Right Thing: The MSK Immigrant Health & Cancer Disparities Service

The MSK Immigrant Health & Cancer Disparities service improves people’s lives in communities that too often get overlooked and suffer disproportionately from cancer, including lack of access to care.