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MSK Research Highlights, June 29, 2023
New MSK research discovered ferroptosis regulators that suggest therapeutic opportunities against hormone receptor-positive cancers; examined how tumor-associated macrophages might be turned against cancer; acquired new insights into joint inflammation in rheumatoid arthritis; developed a systems-level platform called epichaperomics to map changes in interactors among thousands of proteins involved in cancer-related processes; and investigated how artificial intelligence could help diagnose an invasive form of breast cancer.
(From left) Jacy and Nikki on a recent trip to Paris
Celebrating Pride With Authentic Voices
Nikki Chotas, who uses the pronouns they/them, has dedicated much of their life to speaking up for and working to empower those who may feel helpless and without a voice. They attribute their pursuits in part to feeling voiceless in their younger years.
Ask the Expert
Mom and daughter having conversation
10 Tips for Talking with Your Child about Cancer
Find tools for discussing a cancer diagnosis with your children.
In the Lab
Confocal microscopic image of mouse lymphedema tissue with staining for immune cells and lymphatic vessels.
Researchers Zero In on the Cause of Lymphedema, a Debilitating Cancer Complication
Learn how an MSK laboratory is bringing much-needed focus to cancer-related lymphedema and investigating new ways to prevent the complication.
Feature
DNA molecules wrapped around histones
The Future of Cancer Research: Five Reasons for Optimism
Discover some of the most exciting research that Memorial Sloan Kettering scientists are pursuing in the fight against cancer.
Pictured: Joan Massagué
Cancer Biologist Joan Massagué Honored on Two Continents
Joan Massagué, Chair of the Cancer Biology and Genetics Program in the Sloan Kettering Institute, has been named the recipient of two prestigious awards.
In the Lab
Scientist Gabriela Chiosis in her lab
Experimental Drug Targets Misbehaving Proteins in Brain Cancer and Alzheimer’s Disease
Memorial Sloan Kettering researchers are studying how drugs that reverse malfunctioning proteins may treat disease.
Finding
Papillary renal cell carcinoma under the microscope
Study Suggests More People with Kidney Cancer Should Be Screened for Hereditary Cancer Genes
Researchers have found that more than 20% of people with a type of cancer called advanced non-clear cell renal cell carcinoma have disease that is driven by inherited cancer mutations.
In the Lab
Portrait of a live zebrafish with dark patterning around and above the eyes
Uncharted Waters: The Making of a New Cancer Drug
A team of scientists is combining sophisticated chemistry and experiments in zebrafish to develop a new cancer drug that shows early potential against melanoma and metastatic breast cancer.
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Close-up photo of someone walking on the road
Study Shows Patients Are Less Active after Cancer Diagnosis
Learn why some patients are less physically active during and after treatment — plus, some tips from Jun Mao, Chief of the Integrative Medicine Service at MSK.