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Science Byte
Illustration of DNA with green wrench making adjustments to a nut on the double helix.
A Clean Break: Scientists Make Surprising Discoveries about DNA Repair
A study reveals unexpected insights into how cells prepare broken DNA strands to be rejoined, preventing mutations that can cause cancer.
Selwyn M. Vickers, MD, FACS
A Message From MSK’s President and CEO, Dr. Selwyn Vickers
In cancer care, firsts make a difference. At MSK, we are constantly improving how we help people with those important firsts. Dr. Selwyn Vickers writes about the latest developments at MSK and the encouraging evidence that we are making progress in our mission of ending cancer for life.
This screenshot from a video shows an 11-day-old mouse embryo with its internal organs highlighted in fluorescence.
Quantum Leap
MSK investigators are leading the way with approaches so bold they are like the difference between "a snapshot and a movie."
Feature
Molecular biologist John Petrini of the Sloan Kettering Institute.
Understanding the DNA-Damage “First Responders”: John Petrini at Work
Scientists know that cancer can result from mistakes in DNA repair. But understanding what controls the repair process itself has been a hard nut to crack.
In the Lab
Bees in a hive
Communal Behavior within Cells Makes Cancers Easier to Target
Findings about proteins called molecular chaperones are shedding new light on possible approaches to cancer treatment.
Two Fred’s Team runners wearing orange shirts in a crowd
Your Impact: The Society, Fred’s Team, and Virtual Health Education Seminars
Learn about how our donor community is funding life-changing cancer research at Memorial Sloan Kettering and ensuring a brighter future for people with cancer around the world.
Archival photo of Maria Jasin and Mary Ellen Moynahan
From Breaks to Breakthroughs
Maria Jasin’s discoveries have led to concrete advances in patient care. The targeted medicines called PARP inhibitors, for example, are based on knowledge gained from her work.
In the Lab
Black-and-white microscopic image of cell from human granular cell tumor
A Study of Rare Tumors Uncovers the Presence of Tumor-Suppressing Genes
Studying the genes of granular cell tumors has revealed a previously unknown process through which cells can turn cancerous.
Albert Kuchler with MSK medical oncologist Bob Li.
Harnessing the Power of Data for Patient Care
Computational biology is helping to bring predictive power and precision to oncology.
An MSK scientist pipettes in the lab
MSK Research Highlights, May 18, 2023
New MSK research shows how high-risk neuroblastoma evolves to be so deadly; finds continued safety and efficacy for sotorasib in patients with KRAS G12C-mutated advanced non-small cell lung cancer; and demonstrates promise in eradicating tumors by delivering a viral-based immunotherapeutic to melanoma and breast cancer in mouse models.