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In the Clinic
Shanu Modi
FDA Approves First Targeted Drug To Treat HER2-Low Breast Cancer: Trastuzumab Deruxtecan (T-DXd)
On August 5, 2022, the FDA approved the first targeted therapy for patients with HER2-low breast cancer that has spread to other parts of the body and is unable to be surgically removed. The drug, trastuzumab deruxtecan (T-DXd), was approved based on a clinical trial led by Memorial Sloan Kettering Cancer Center (MSK) breast medical oncologist Shanu Modi.
In the Lab
Image of dividing breast cancer cells taken with electron microscope.
Researchers Identify Why Women May Develop Resistance to a New Class of Breast Cancer Drugs
Clues emerge about why promising new breast cancer drugs sometimes don’t work — and what might be done about it.
Boris Mueller, MD, Director, Radiation Oncology at MSK Bergen is seen standing in a hallway.
Breast Cancer and Tattoo-Less Radiation at MSK
Learn how people with early stage breast cancer can receive radiation therapy without the need for tattoos at Memorial Sloan Kettering Cancer Center.
In the News
Man meets with a doctor
FDA Recommends Including Men in Breast Cancer Trials
The recommendation comes in the form of draft guidelines open for public comment until October 2019.
Finding
Kate Delp standing on the beach, smiling and holding a yoga mat
Why More People With Breast Cancer Are Choosing Lumpectomy Over Mastectomy: Kate’s Story
An MSK study found a rise in lumpectomies and a decline in mastectomies — reversing a trend that experts say was leading to the overtreatment of breast cancer.
In the Clinic
Two female healthcare professionals performing a mammogram on a patient
For Less Familiar Gene Mutations Linked to Breast Cancer, Research Aims to Create Screening Guidelines
Computer models suggest breast cancer screening guidelines for people with mutations in the genes ATM, CHEK2, and PALB2.
Memorial Sloan Kettering physician-researches Neil Iyengar, Amy Xu, and Joshua Drago
Updates from SABCS 2021: Personalizing Diet and Exercise Plans for Breast Cancer, Zapping Metastatic Cells, Making Targeted Drugs Work Better
MSK physicians and researchers discussed the latest trends in breast cancer research at the annual meeting held in San Antonio.
In the Clinic
Head shot of doctor with glasses, white shirt, and blue tie in his lab.
Drug Reduces Recurrence Risk in Subset of Women with Breast Cancer
A drug was shown to improve outcomes in women with HER2-positive early breast cancer when added to standard therapy.
Reilly Starr with her husband and their son on her husband's shoulders
Always by Your Side: How MSK Helps People Facing Metastatic Breast Cancer
Learn how people facing metastatic breast cancer help each other in support groups at Memorial Sloan Kettering.
In the Clinic
Medical oncologist Mark Robson
Phase III Trial of Targeted Drug Shows Promise in Treating Metastatic Breast Cancer
Investigators found that olaparib extended progression-free survival by an average of three months in women with advanced breast cancer.