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444 News Items found
Feature
Female doctor in white coat examining patient with stethoscope.
Shorter, Safer, Smarter: How MSK Enhances Radiation Therapy for Breast Cancer

MSK leads the way in optimizing radiation treatment for breast cancer patients.
In the Lab
Pathology slide showing DCIS and invasive cancer
Forensic Techniques Enable Study of Individual Breast Cancer Cells from MSK’s Archives

Analysis of long-preserved single cells on pathology slides aims to provide new clues about the genes that make breast cancer more aggressive.
In the Clinic
Melissa Zinovoy, right, and chief radiation therapist Beeban Natt
Radiation Greatly Reduces Risk of Recurrence for Women with DCIS, a Type of Noninvasive Breast Cancer

Radiation therapy after surgery can sharply reduce the chance that certain low-risk breast cancers will return.
Feature
Cartoon of different-color heads with speaker and thought bubbles above them.
What You Should Know about Five Common Cancers

Even the most common cancers have aspects that are not fully grasped by the public.
In the Lab
Scanning electron microscope image of a breast cancer cell.
Mutations in the Same Gene Create Different Paths to Breast Cancer Drug Resistance

A new finding provides insight into how breast cancer develops resistance to aromatase inhibitors.
In the Clinic
A photo of Paula with her dog; Paula in a graduation cap and gown; Paula at a pottery wheel; and Paula snowboarding.
How a Targeted Drug Developed for Breast Cancer Is Helping People with Lung Cancer

A phase II trial of the targeted therapy trastuzumab deruxtecan (Enhertu®) has found that the drug shrinks tumors in more than half of people with advanced lung cancer driven by the protein HER2.
Finding
Illustration of breast encompassing blue normal cells and red cancer cells.
A Missing Link Revealed: Researchers Gain Insight into Breast Cancer Drug Resistance

Researchers find an epigenetic role in how breast cancer tumors develop resistance to treatment.
MSK Researchers Identify First Evidence of Epigenetic Role in Breast Cancer

Researchers at Memorial Sloan Kettering Cancer Center have identified, for the first time, an epigenetic mechanism promoting breast cancer. The team found that inhibition of the PI3K pathway leads to activation of ER-dependent transcription through the epigenetic regulator KMT2D. These findings provide a rationale for epigenetic therapy in patients with PIK3CA-mutant, ER-positive breast cancer. While epigenetic factors have been known to play an important role in various cancers such as leukemia and lymphoma, this is the first evidence found in breast cancer. This research co-led by José Baselga, MD, PhD, Physician-in-Chief and Chief Medical Officer, appears in the March 24, 2017 issue of Science. For more information on this work and to speak with the study authors, contact [email protected].
In the Clinic
Surgeon in scrubs operating on patient.
Study Findings Could Help Women Make Decisions about Breast Cancer Surgery

Women who have reconstructive surgery after mastectomy and radiation for breast cancer are usually more satisfied with the results when their own tissue is used instead of implants.
Finding
Pictured: Kenneth Offit
New Findings May Lead to Better Predictions of Breast Cancer Risk in Women with Inherited Mutations

A study identifies genetic variations that alter the risk of breast cancer in women who have a certain gene mutation.