Memorial Hospital Research Laboratories
The Christine Iacobuzio-Donahue Lab
Research
![Christine Iacobuzio-Donahue](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/34597/main_image/gsk_210722_271_rt-1200x800.jpg?h=38fd8c93)
Our lab investigates the fundamental evolutionary mechanisms underlying metastasis using pancreatic cancer as our model tumor type. Metastasis is the result of a series of biological hurdles subject to Darwinian selection including the birth of metastasis-enabled cells within a heterogeneous primary tumor microenvironment, intravasation of these cells into a functional vascular bed, survival in the circulation, extravasation from the vasculature, and establishment of an autonomous cell population within the newly encountered foreign microenvironment.
![The Christine Iacobuzio-Donahue Lab](https://www.mskcc.org/sites/default/files/node/34597/3x2/iacobuzio_160607_06_3x2.jpg)
Featured News
![MSK pathologist Christine Iacobuzio-Donahue](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/148267/3x2/iaco-1200x800.jpg)
![A pancreatic cancer cell](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/133549/3x2/pancreatic-cancer-cell.jpg)
Publications Highlights
People
![Christine Iacobuzio-Donahue](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/34597/main_image/gsk_210722_271_rt-1200x800.jpg?h=38fd8c93)
Christine A. Iacobuzio-Donahue, MD, PhD
David M. Rubenstein Center Chair for Pancreatic Cancer Research; Director, Center for Pancreatic Cancer Research
- Physician-scientist Christine Iacobuzio-Donahue studies the genomics and cell biology of pancreatic and other solid tumors as it relates to subclonal evolution, tumor progression, and metastasis.
- MD, PhD, Boston University
- View physician profile
- Physician profile
Members
![Jungeui Hong](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/103574/3x2/hong2.jpg?h=10d202d3)
![Elias-Ramzey Karnoub](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/244858/main_image/karnoub-elias-ramzey-220414-022_1200x800.jpg?h=10d202d3)
![Helen Martirosova](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/200680/main_image/martirosova-helen_191028_11-1200x800.jpg?h=10d202d3)
![Katelyn Mullen](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/161107/main_image/mullen-katelyn_191028_10-1200x800.jpg?h=10d202d3)
- BS, University of Massachusetts – Amherst
![Wungki Park](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/244933/main_image/park-wungki-220414-010_1200x800.jpg?h=10d202d3)
![Shigeaki Umeda](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/200683/main_image/umeda-shigeaki_210309_008_rt-1200x800.jpg?h=10d202d3)
![Haochen Zhang](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/244867/main_image/zhang-haochen-220414-017_1200x800.jpg?h=10d202d3)
Research Assistant
Senior Research Technician
![Jungeui Hong](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/103574/3x2/hong2.jpg?h=10d202d3)
Senior Research Scientist
![Rajya Kappagantula](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/124183/3x2/kappagantula_160607_10_3x2.jpg?h=10d202d3)
Research Assistant
![Elias-Ramzey Karnoub](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/244858/main_image/karnoub-elias-ramzey-220414-022_1200x800.jpg?h=10d202d3)
Senior Research Technician
Research Technician
Senior Research Scientist
![Helen Martirosova](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/200680/main_image/martirosova-helen_191028_11-1200x800.jpg?h=10d202d3)
Research Fellow
![Jerry Melchor](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/34599/3x2/melchor_3x2.jpg?h=10d202d3)
Lead Program Manager
GSK Graduate Student
![Katelyn Mullen](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/161107/main_image/mullen-katelyn_191028_10-1200x800.jpg?h=10d202d3)
Graduate Student
Research Fellow
![Wungki Park](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/244933/main_image/park-wungki-220414-010_1200x800.jpg?h=10d202d3)
Assistant Attending
Assistant Attending
Senior Research Scientist
![Shigeaki Umeda](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/200683/main_image/umeda-shigeaki_210309_008_rt-1200x800.jpg?h=10d202d3)
Senior Research Scientist
![Haochen Zhang](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/244867/main_image/zhang-haochen-220414-017_1200x800.jpg?h=10d202d3)
GSK Graduate Student
![Alexandra Miller](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/164032/3x2/miller-alexandra_180820_12_1200x800.jpg?h=10d202d3)
![Priscilla Baez](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/138478/3x2/baez_170421_11_3x2.jpg?h=10d202d3)
![Akimasa Hayashi](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/138481/3x2/hayashi_170421_08_3x2.jpg?h=10d202d3)
![Alvin Makohon-Moore](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/103578/3x2/makohon2.jpg?h=10d202d3)
![Chelsea Michael](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/35451/image/michael-chelsea.jpg)
![Hope Narozniak](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/220327/main_image/narozniak-hope_210309_002-1200x800.jpg?h=10d202d3)
![Amanda Zucker](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/200677/main_image/zucker-amanda_191028_07-1200x800.jpg?h=10d202d3)
Lab Alumni
![Alexandra Miller](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/164032/3x2/miller-alexandra_180820_12_1200x800.jpg?h=10d202d3)
Assistant Attending
![Marc Attiyeh](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/124180/3x2/attiyeh_160607_04_3x2.jpg?h=10d202d3)
Research Fellow
![Priscilla Baez](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/138478/3x2/baez_170421_11_3x2.jpg?h=10d202d3)
Research Project Associate
![Jun Fan](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/124189/3x2/fan_160607_05_3x2.jpg?h=10d202d3)
Research Associate
![Akimasa Hayashi](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/138481/3x2/hayashi_170421_08_3x2.jpg?h=10d202d3)
Visiting Investigator
![Jinlong Huang](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/124186/3x2/huang_160607_12_3x2.jpg?h=10d202d3)
Research Fellow
![Zachary Kohutek](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/34602/image/kohutek-zachary.jpg?h=10d202d3)
Assistant Attending Radiation Oncologist
![Alicia Maisonet](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/35454/3x2/maisonet_3x2.jpg?h=10d202d3)
Program Assistant
![Alvin Makohon-Moore](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/103578/3x2/makohon2.jpg?h=10d202d3)
Research Associate
![Breanna McMahon](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/39051/image/breanna-mcmahon-3x2.jpg)
Research Technician
![Chelsea Michael](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/35451/image/michael-chelsea.jpg)
Clinical Coordinator
![Salvador Suarez Naranjo](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/34600/image/salvador-suarez-naranjo.jpg)
Research Associate
![Hope Narozniak](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/220327/main_image/narozniak-hope_210309_002-1200x800.jpg?h=10d202d3)
Research Technician
![Derwin Pena](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/35453/3x2/pena.jpg?h=10d202d3)
Morgue Attendant
![Hitomi Sakamoto](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/39052/3x2/sakamoto.jpg?h=10d202d3)
Research Fellow
![Efsevia Vakiani, MD, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/6079/image/vakiani-efsevia.jpg?h=10d202d3)
Assistant Attending Pathologist
![Liguo Zhang](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/39053/image/liguo-zhang-3x2.jpg?h=10d202d3)
Senior Research Technician
![Yi Zhong](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/34601/image/zhong-yi.jpg?h=10d202d3)
Research Associate
![Amanda Zucker](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/200677/main_image/zucker-amanda_191028_07-1200x800.jpg?h=10d202d3)
Research Technician
Lab Affiliations
Achievements
- Team Science Award, American Association for Cancer Research (2012)
- Ramzi Cotran Young Investigator Award, United States and Canadian Academy of Pathology (2009)
- AACR-Barletta Foundation Career Development Award in Translational Pancreatic Cancer Research (2005)
- Member, Alpha Omega Alpha (2002)
- American Society of Clinical Investigators (2015)
Read more
- Elected to American Association of University Pathologists (Pluto Society)
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs
Career Opportunities
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Christine A. Iacobuzio-Donahue discloses the following relationships and financial interests:
-
Bristol-Myers Squibb
Professional Services and Activities (Uncompensated)
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].