Epidemiology & Biostatistics
The Elli Papaemmanouil Lab
Research
![Eli Papemmanuil](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/39611/person/papaemmanuil_3x2.jpg?h=10d202d3)
Our lab is a collective of clinical, computational, molecular and mathematic research investigators with an interest in studying the role of acquired mutations in cancer development, and how these determine clinical phenotype and response to therapy. Our mission is to execute research that informs and moves clinical practices in oncology forward. We have strong expertise in genome profiling analysis, a proven track record on the development of high-throughput laboratory and analytical pipelines (bioinformatics and statistical), and integrating large and complex genomic datasets. We have formed a strong network of research and clinical collaborations to pursue innovative studies in cancer research.
We like to perform ambitious research, but operate in a fun, collaborative, and team-oriented environment, and we are strongly committed to mentoring young scientists through internal and international internship schemes.
Research Projects
![The Elli Papaemmanuil Lab](https://www.mskcc.org/sites/default/files/node/39611/3x2/papaemmanuil-lab-group_190905_08_1200x800.jpg)
Featured News
![MSK scientists Andrew Kung and Elli Papaemmanouil](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/245512/main_image/kungpapaemmanuil-12x8.jpg)
![Molecular geneticist Elli Papaemmanouil](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/123277/main_image/2017msk_mp_10_epibiolab_085.nef.p2.1200x800.jpg)
![MSK molecular geneticist Elli Papaemmanouil](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/201502/main_image/2017msk_mp_10_epibiolab_084.nef.p2-1200x800.jpg)
Publications Highlights
Duncavage EJ, Bagg A, Hasserjian RP, DiNardo CD, Godley LA, Iacobucci I, Jaiswal S, Malcovati L, Vannucchi AM, Patel KP, Arber DA, Arcila ME, Bejar R, Berliner N, Borowitz MJ, Branford S, Brown AL, Cargo CA, Döhner H, Falini B, Garcia-Manero G, Haferlach T, Hellström-Lindberg E, Kim AS, Klco JM, Komrokji R, Lee-Cheun Loh M, Loghavi S, Mullighan CG, Ogawa S, Orazi A, Papaemmanouil E, Reiter A, Ross DM, Savona M, Shimamura A, Skoda RC, Solé F, Stone RM, Tefferi A, Walter MJ, Wu D, Ebert BL, Cazzola M. Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia. Blood. 2022 Nov 24;140(21):2228-2247. doi: 10.1182/blood.2022015853. PMID: 36130297; PMCID: PMC10488320.
Kinnaman MD, Zaccaria S, Makohon-Moore A, Arnold B, Levine M, Gundem G, Arango Ossa JE, Glodzik D, Rodríguez-Sánchez MI, Bouvier N, Li S, Stockfisch E, Dunigan M, Cobbs C, Bhanot U, You D, Mullen K, Melchor J, Ortiz MV, O’Donohue T, Slotkin E, Wexler LH, Dela Cruz FS, Hameed M, Glade Bender JL, Tap WD, Meyers PA, Papaemmanouil E, Kung AL, Iacobuzio-Donahue CA. Subclonal somatic copy number alterations emerge and dominate in recurrent osteosarcoma. bioRxiv [Preprint]. 2023 Jan 24:2023.01.05.522765. doi: 10.1101/2023.01.05.522765. PMID: 36711976; PMCID: PMC9881990.
Al Assaad M, Gundem G, Liechty B, Sboner A, Medina J, Papaemmanouil E, Sternberg CN, Marks A, Souweidane MM, Greenfield JP, Tran I, Snuderl M, Elemento O, Imielinski M, Pisapia DJ, Mosquera JM. The importance of escalating molecular diagnostics in patients with low-grade pediatric brain cancer. Cold Spring Harb Mol Case Stud. 2023 Aug 31:mcs.a006275. doi: 10.1101/mcs.a006275. Epub ahead of print. PMID: 37652664.
Bolton KL, Chen D, Corona de la Fuente R, Fu Z, Murali R, Köbel M, Tazi Y, Cunningham JM, Chan ICC, Wiley BJ, Moukarzel LA, Winham SJ, Armasu SM, Lester J, Elishaev E, Laslavic A, Kennedy CJ, Piskorz A, Sekowska M, Brand AH, Chiew YE, Pharoah P, Elias KM, Drapkin R, Churchman M, Gourley C, DeFazio A, Karlan B, Brenton JD, Weigelt B, Anglesio MS, Huntsman D, Gayther S, Konner J, Modugno F, Lawrenson K, Goode EL, Papaemmanouil E. Molecular Subclasses of Clear Cell Ovarian Carcinoma and Their Impact on Disease Behavior and Outcomes. Clin Cancer Res. 2022 Nov 14;28(22):4947-4956. doi: 10.1158/1078-0432.CCR-21-3817. PMID: 35816189; PMCID: PMC9777703.
Diamond B, Ziccheddu B, Maclachlan K, Taylor J, Boyle E, Ossa JA, Jahn J, Affer M, Totiger TM, Coffey D, Chandhok N, Watts J, Cimmino L, Lu SX, Bolli N, Bolton K, Landau H, Park JH, Ganesh K, McPherson A, Sekeres MA, Lesokhin A, Chung DJ, Zhang Y, Ho C, Roshal M, Tyner J, Nimer S, Papaemmanouil E, Usmani S, Morgan G, Landgren O, Maura F. Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures. Blood. 2023 May 11;141(19):2359-2371. doi: 10.1182/blood.2022018244. PMID: 36626250; PMCID: PMC10273163.
People
![Eli Papemmanuil](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/39611/person/papaemmanuil_3x2.jpg?h=10d202d3)
Elli Papaemmanouil, PhD
Associate Attending
- Molecular geneticist Elli Papaemmanouil performs systematic interrogations of well-annotated clinical trial cohorts in leukemia and cancer to explore how the compound genetic and clonal architecture in patients' leukemias and tumors dictate clinical phenotype, disease progression, and clinical outcomes.
- PhD – University of London, London, England, UK
- [email protected]
- Email Address
- 646-608-7645
- Office Phone
Members
![Konstantinos Liosis](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/244387/main_image/liosis-konstantinos-220310-016_1200x800.jpg?h=10d202d3)
Computational Biologist II
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150292/main_image/arango-ossa-juan_190905_06_0.jpg?h=242cd5c8)
Bioinformatics Software Engineer IV
![Georgios Asimomitis, Computational Biologist II](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/207442/main_image/asimomitis-georgios_190905_09.jpg?h=242cd5c8)
Computational Biologist II
![Elsa Bernard, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/160627/3x2/bernard_170926_03_1200x800.jpg?h=10d202d3)
Research fellow
![Dylan Domenico](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/211855/main_image/domenicao-dylan_210519_06-1200x800.jpg?h=10d202d3)
Bioinformatics Software Engineer II
![Gunes Gundem](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/39615/3x2/gundem_170926_01_1200x800.jpg?h=10d202d3)
Principal Computational Biologist
![Jesus Gutierrez-Abril](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/207445/main_image/gutierrez-abril-jesus_190905_06.jpg?h=242cd5c8)
Research Associate
![Konstantinos Liosis](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/244387/main_image/liosis-konstantinos-220310-016_1200x800.jpg?h=10d202d3)
Bioinformatics Engineer I
![Joseph G. McCarter](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/161449/3x2/mccarter_joseph_180611_09_1200x800.jpg?h=10d202d3)
Senior Computational Biologist II
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/236362/main_image/genesis-pineda-headshot2.png?h=242cd5c8)
Senior Administrative Assistant
![Noushin Rahnamay Farnoud](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150415/3x2/farnoud_130612_02_1200x800.jpg?h=10d202d3)
Principal Computational Biologist
![Sarun Sereewattanawoot](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/225859/main_image/sereewattanawoot-sarun_210519_07-1200x800.jpg?h=10d202d3)
Research Associate
![Charlotte Brierley](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/244270/main_image/brierley-charlotte-220405-13_1200x800.jpg?h=10d202d3)
![Dominik Glodzik](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/161443/3x2/glodzik_dominik_180611_13_1200x800.jpg?h=10d202d3)
![Yoann Pradat, Graduate Research Asst](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/153934/3x2/pradat-yoann_180320_08_1200x800.jpg)
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/125509/main_image/sirenko_1200x800.jpg?h=10d202d3)
- BS, Cornell University
![Elliot Youth](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/161434/3x2/youth_elliot_180611_06_1200x800.jpg?h=10d202d3)
Lab Alumni
Administrative Assistant II
Graduate Research Assistant
![Maheetha Bharadwaj, Computational Biologist I](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/147439/3x2/bharadwaj_170926_10_1200x800.jpg?h=10d202d3)
Computational Biologist I
![Kelly Bolton](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150418/3x2/bolton_170926_03.jpg?h=242cd5c8)
Instructor
![Charlotte Brierley](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/244270/main_image/brierley-charlotte-220405-13_1200x800.jpg?h=10d202d3)
Graduate Research Assistant
Graduate Research Assistant
![Robert de Massy](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/116524/3x2/marc-robert-de-massy_3x2.jpg)
Visiting scientists
![Andre Deslauriers, Graduate Research Asst](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150280/3x2/deslauriers_170926_10_1200x800.jpg?h=10d202d3)
Graduate Research Assistant
![Teng Gao](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/161440/3x2/gao_teng_180611_02_1200x800.jpg?h=10d202d3)
Computational Biologist II
![Dominik Glodzik](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/161443/3x2/glodzik_dominik_180611_13_1200x800.jpg?h=10d202d3)
Associate Manger, Computational Biologist
Graduate Research Assistant
![Max Levine](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150283/3x2/levine_170926_08_1200x800.jpg?h=10d202d3)
Senior Computational Biologist I
![Juan Medina](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/116518/3x2/median_161213_03_1200x800.jpg?h=10d202d3)
Bioinformatics Engineer II, Leukemia Genomics
![Matahi Moarii, Postdoctoral Fellow](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/116515/3x2/moarii_170926_03_1200x800.jpg?h=10d202d3)
Research Fellow
![Yoann Pradat, Graduate Research Asst](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/153934/3x2/pradat-yoann_180320_08_1200x800.jpg)
Graduate Research Asst
![Komal Rathi](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/116521/3x2/komal-rathi_3x2.jpg?h=10d202d3)
Bioinformatics Engineer II, Leukemia Genomics
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/125509/main_image/sirenko_1200x800.jpg?h=10d202d3)
Postdoctoral Fellow, NYU Langone, New York, NY
![Yanis Tazi, Graduate Student, Tri-I Institutional PhD Program](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/207454/main_image/33200958.jpeg?h=c35ab9d9)
Graduate Student, Tri-I Institutional PhD Program
![Yellapantula Venkata, Bioinformatics Engineer II](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150286/3x2/yellapantula_170926_02_1200x800.jpg?h=10d202d3)
Bioinformatics Engineer II
![Elliot Youth](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/161434/3x2/youth_elliot_180611_06_1200x800.jpg?h=10d202d3)
Intern
![Yangyu Zhou, Bioinformatics Engineer I](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/150289/3x2/zhou_180103_15_1200x800.jpg?h=10d202d3)
Bioinformatics Engineer II
Lab Affiliations
Achievements
- Josie Robertson Investigator (2015-2020)
- European Hematology Association Young Investigator Award
- Cancer Research UK Career Development Award
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs
Bioinformatics Data Scientist
Careers
Molecular genomics, Research Assistant / Senior Research Technician
Get in Touch
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Lab Head Email
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Office Phone
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Elli Papaemmanouil discloses the following relationships and financial interests:
-
Isabl Inc.
Equity; Fiduciary Role / Position; Intellectual Property Rights
-
TenSixteen Bio, Inc.
Equity; Professional Services and Activities
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].