Memorial Hospital Research Laboratories
The Luke Pike Lab
Research
![Luke Pike](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250226/main_image/pike-luke_200915_09_1200x800.jpg?h=6f3285a6)
The Luke Pike Lab seeks to understand the unique biology of brain metastasis (BM) to improve outcomes for patients afflicted with various solid tumors. BM is exceptionally common, with an estimated 400,000 patients diagnosed yearly in the U.S. The mechanisms by which cancer cells spread to and survive in the brain are poorly understood. The standard treatment for BM has been radiation therapy with or without surgical resection, as most drug therapies are ineffective against BM. New drugs, such as immune checkpoint or targeted inhibitors, have shown promising activity against BM, but our understanding of why they often fail in the brain is incomplete. The Pike Lab uses cutting-edge molecular techniques to understand tumor tropism for the brain and to identify features of human BM that might lead to drug or radiation resistance and the survival of cancer cells in the brain tumor microenvironment.
![Luke Pike Lab group outing](https://www.mskcc.org/sites/default/files/node/250226/images/lab-group-photo_1200x800.jpg)
Publications Highlights
People
![Luke Pike](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250226/main_image/pike-luke_200915_09_1200x800.jpg?h=6f3285a6)
Luke Pike, MD, DPhil
- Physician-scientist Luke R.G. Pike studies the mechanistic underpinnings of brain metastasis and seeks to identify translational correlates with outcomes following local or systemic therapy.
- DPhil/PhD, Medical Oncology, University of Oxford
- MD, Yale School of Medicine
- [email protected]
- Email Address
- View physician profile
- Physician profile
Members
![Kevin Boehm](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/166249/3x2/boehm-kevin_008_1200x800.jpg?h=10d202d3)
- PhD, Gerstner School of Graduate Sciences, Memorial Sloan Kettering
- MD, Weill Medical College, Cornell University (Tri-I MD-PhD)
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/266536/main_image/cederquist-gustau_210723_014-1200x800.jpg?h=10d202d3)
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/266441/main_image/cooper.jpg)
![Luke del Balzo](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250231/main_image/del-balzo-headshot_1200x800.jpg?h=10d202d3)
![Jordan Eichholz](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250241/main_image/eichholz-jordan-211208-014-2-_1200x800.jpg?h=10d202d3)
![Benjamin Gaeta](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250251/main_image/gaeta-benjamin_1200x800.png?h=06d78ab6)
![Chengcheng Gui](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250276/main_image/guichengchengheadshot_1200x800.jpg?h=10d202d3)
![Ishaani Khatri](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250281/main_image/ishaanikhatri_headshot_1200x800.jpg?h=10d202d3)
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/266531/main_image/rahul-kumar.jpg)
![Emily Lebow](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250261/main_image/lebow-headshot_1200x800.jpg?h=10d202d3)
![Jennifer Ma](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250236/main_image/jennifer-ma_1200x800.jpg)
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/266431/main_image/amandeep.jpg)
![Emily Miao](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250246/main_image/emily_miao_1200x800.jpg?h=10d202d3)
![Anna Skakodub](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250266/main_image/shot_anna-skakodub_1200x800.jpg?h=10d202d3)
![Kathryn Tringale](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250256/main_image/tringale-headshot_1200x800.jpg?h=10d202d3)
![Kevin Boehm](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/166249/3x2/boehm-kevin_008_1200x800.jpg?h=10d202d3)
Postdoctoral Fellow, Computational Oncology; Resident Physician, Radiation Oncology
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/266536/main_image/cederquist-gustau_210723_014-1200x800.jpg?h=10d202d3)
Memorial Sloan Kettering RO PGY3
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/266441/main_image/cooper.jpg)
Intern
![Luke del Balzo](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250231/main_image/del-balzo-headshot_1200x800.jpg?h=10d202d3)
Medical College of Georgia MS3
![Jordan Eichholz](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250241/main_image/eichholz-jordan-211208-014-2-_1200x800.jpg?h=10d202d3)
Project Coordinator
![Benjamin Gaeta](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250251/main_image/gaeta-benjamin_1200x800.png?h=06d78ab6)
Cornell MS3
![Chengcheng Gui](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250276/main_image/guichengchengheadshot_1200x800.jpg?h=10d202d3)
Memorial Sloan Kettering RO PGY3
![Ishaani Khatri](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250281/main_image/ishaanikhatri_headshot_1200x800.jpg?h=10d202d3)
Brown MS2
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/266531/main_image/rahul-kumar.jpg)
Undergraduate, University of Miami
![Emily Lebow](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250261/main_image/lebow-headshot_1200x800.jpg?h=10d202d3)
Memorial Sloan Kettering RO PGY5
![Jennifer Ma](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250236/main_image/jennifer-ma_1200x800.jpg)
Memorial Sloan Kettering RO PGY4
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/266431/main_image/amandeep.jpg)
Harvard Radiation Oncology Program, PGY3
![Emily Miao](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250246/main_image/emily_miao_1200x800.jpg?h=10d202d3)
Albert Einstein MS3
Yale Undergrad
![Anna Skakodub](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250266/main_image/shot_anna-skakodub_1200x800.jpg?h=10d202d3)
Pennsylvania State College of Medicine MS3
![Kathryn Tringale](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/250256/main_image/tringale-headshot_1200x800.jpg?h=10d202d3)
Memorial Sloan Kettering RO PGY5
Memorial Sloan Kettering PGY1
Lab Alumni
Memorial Sloan Kettering RO PGY3
Lab Affiliations
Achievements
- Alexander Graham Bell PhD Scholarship (2009)
- The Rhodes Scholarship (2007)
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs
Get in Touch
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Lab Head Email
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Luke Pike discloses the following relationships and financial interests:
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Dxcover Limited
Professional Services and Activities (Uncompensated) -
Genece Health, Inc.
Professional Services and Activities (Uncompensated)
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Monograph Capital Advisors, L.P.
Professional Services and Activities
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].