Benoît Rousseu, MD, PhD

Assistant Attending
The Luis Diaz Jr. Lab
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Publications

Benoît Rousseu, MD, PhD

Assistant Attending
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Benoît Camelli-Rousseau

My research interests are in creating innovative immunomodulatory options for patients with immunologically “cold” tumors with a particular interest in antigens processing and maturation. Using in vitro and pre-clinical methods we are identifying ways of generating a “cold-to-hot” immune environment, with the goal of translating these results into a clinical trial.

Publications

Rousseau B, Guillemin A, Duvoux C, Neuzillet C, Tlemsani C, Compagnon P, Azoulay D, Salloum C, Laurent A, de la Taille A, Salomon L, Cholley I, Haioun C, Dupuis J, Wolkenstein P, Matignon MB, Grimbert P, Tournigand C. Optimal oncologic management and mTOR inhibitor introduction are safe and improve survival in kidney and liver allograft recipients with de novo carcinoma. Int J Cancer. 2019 Feb 15;144(4):886-896.

Calderaro J, Petitprez F, Becht E, Laurent A, Hirsch T, Rousseau B, Amaddeo G, Derman J, Charpy C, Zucman-Rossi J, Fridman WH, Sautès Fridman C. Intra-tumor tertiary lymphoid structures are associated with a low risk of early tumor recurrence in patients with hepatocellular carcinoma. J Hepatol. 2019 Jan;70(1):58-65.

Bourdais R, Rousseau B, Pujals A, Boussion H, Joly C, Guillemin A, Baumgaertner I, Neuzillet C, Tournigand C. Polymerase proofreading domain mutations: New opportunities for immunotherapy in hypermutated colorectal cancer beyond MMR deficiency. Crit Rev Oncol Hematol. 2017 May;113:242-248.

J Fontugne, J Augustin, Anaïs Pujals, P Compagnon, B Rousseau, A Luciani, C Tournigand, D Cherqui, D Azoulay, JM Pawlotsky, J Calderaro. PD-L1 expression in perihilar and intrahepatic cholangiocarcinoma. Oncotarget. 2017 Apr 11;8(15):24644-24651.

J Calderaro, B Rousseau, G Amaddeo, M Mercey, C Charpy, C Costentin, A Luciani, ES Zafrani, A Laurent, D Azoulay, F Lafdil, JM Pawlotsky, PD‐L1 expression in hepatocellular carcinoma: Relationship with clinical and pathological features. Hepatology. 30 June 2016.

B. Rousseau, P. Loulergue, O. Mir et al. Immunogenicity and safety of the influenza A H1N1v 2009 vaccine in cancer patients treated with cytotoxic chemotherapy and/or targeted therapy: the Vacance study. Ann Oncol. 2012 Feb;23(2):450-7. Epub 2011 May 16.