Hospital Research Teams
Laboratory for Innovation in Breast Cancer - LANTERN
Overview
Lior Z. Braunstein
Radiation Oncologist, Program Director
The Laboratory for Innovation in Breast Cancer transforms cutting-edge research into better outcomes for patients. Our multidisciplinary team - radiation oncologists, surgical oncologists, medical oncologists, biostatisticians, geneticists, and clinical researchers - collaborates to bridge the gap between scientific discovery and patient care. We combine deep clinical expertise with rigorous scientific investigation, conducting both translational research and clinical trials to advance cancer care. This integrated approach allows us to rapidly translate promising findings into novel treatment options for our patients.
Our projects
- The HERO trial (NRG BR008): a phase III trial investigating the optimization of radiation therapy in low-risk, HER2 positive breast cancer patients to characterize the benefit of radiotherapy in this population.
- We are conducting a phase I trial to identify the maximal tolerated dose of abemaciclib when administered concurrently with palliative radiation therapy in patients with metastatic breast cancer.
- We are creating and piloting a large language model (LLM)-based approach to improve the efficiency and scale of clinical trial screening, utilizing a human-in-the-loop model to train AI to accurately screen complex oncology documentation and identify patients eligible for a wide range of clinical trials.
- The PRECISION Trial: a phase II study of radiotherapy omission for low-risk, hormone receptor positive breast cancer deemed low-risk by PAM-50.
- The ARCHER Trial: a phase II randomized trial for patients with HER2-positive oligometastatic breast cancer, investigating the efficacy of local consolidative therapy to mitigate metastatic progression and improve long term outcomes.
People
Radiation Oncologist, Program Director
Members
Associate Attending, Radiation Oncology
Resident, Radiation Oncology
Senior Flow Cytometry Analyst, Pathology and Laboratory Medicine
Associate Attending, Radiation Oncology
Resident, Radiation Oncology
Clinical Research Coordinator, Radiation Oncology
Resident, Radiation Oncology
Chief, Attending, Medical Physics
Resident, Radiation Oncology
Associate Attending, Radiation Oncology
Resident, Radiation Oncology
MD-PhD Student
Resident, Radiation Oncology
Assistant Attending, Radiation Oncology
Resident, Radiation Oncology
Assistant Attending, Pathology and Laboratory Medicine
Research Student
Resident
Resident
Research Student
Resident