Cancer Metabolism

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A cell structure called mitochondrion imaged by transmission electron microscopy. Within mitochondria, sugars and fats are oxidized to produce energy needed for diverse cell functions.

A cell structure called mitochondrion imaged by transmission electron microscopy. Within mitochondria, sugars and fats are oxidized to produce energy needed for diverse cell functions. 

One approach to killing cancer cells is starving them to death by preventing them from getting nutrients, especially glucose. Our investigators anticipate that deciphering how cancer cells access and use fuel will enable development of new treatments. Another focus is the link between obesity and cancer and how the body’s metabolism may spur tumor growth.