View a full listing of Alex Kentsis: Publications’ journal articles. Kazansky Y, Mueller HS, Cameron D, Demarest P, Zaffaroni N, Arrighetti N, Zuco V, Mundi PS, Kuwahara Y, Somwar R, Qu R, Califano A, de Stanchina E, Dela Cruz FS, Kung AL, Gounder MM, Kentsis A. Epigenetic targeting of PGBD5-dependent DNA damage in SMARCB1-deficient sarcomas. bioRxiv. Jubierre L, Rodriguez Fos, Planas-Felix, Lewis, Cameron, Demarest, Nabila, Zhao, Bergin, Reed, Yamada, Socci, Hayes, Rabadan, Torrents, Kruer, Toth, Kentsis A. A transposase-derived gene required for human brain development. bioRxiv.Bigot Y, Yamada M, Mueller H, Morell V, Alves S, Lecomte T, Kentsis A. Analysis of DNA transposition by DNA transposases in human cells. bioRxiv.Takao S, Morell V, Brown FC, Koche R, Kentsis A. Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance. bioRxiv.Kazansky Y, Cameron D, Mueller HS, Demarest P, Zaffaroni N, Arrighetti N, Zuco V, Kuwahara Y, Somwar R, Ladanyi M, Qu R, de Stanchina E, Dela Cruz FS, Kung AL, Gounder MM, Kentsis A. Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy. Cancer Discovery, 2024. Yamada M, Keller R, Cameron D, Suzuki H, Sanghrajka R, Vaynshteyn J, Gerwin J, Maura F, Hooper W, Shah M, Robine N, Demarest P, Bayin SN, Jubierre L, Reed C, Taylor MD, Joyner AL, Raju PG, Kentsis A. Childhood cancer mutagenesis caused by transposase-derived PGBD5. Science Advances, 2024.Kwok N, Aretz Z, Takao S, Ser Z, Cifani P, Kentsis A. Integrative proteogenomics using ProteomeGenerator2. J Proteome Research, 2023Agulnik A et al, SAFER Ukraine Collaborative including Kentsis A. Global effort to evacuate Ukrainian children with cancer and blood disorders who have been affected by war. Lancet Haematology, 2022Cifani P, Kentsis A. Quantitative Cell Proteomic Atlas: Pathway-scale targeted mass spectrometry for high-resolution functional profiling of cell signaling. J Proteome Research, 2022Heikamp EB, Henrich JA, Perner F, Wong EM, Hatton C, Wen Y, Barwe SP, Gopalakrishnapillai A, Xu H, Uckelmann HJ, Takao S, Kazansky Y, Pikman Y, McGeehan GM, Kolb EA, Kentsis A, Armstrong SA. The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML. Blood, 2022Cifani P, Kentsis A. Automated Multidimensional Nanoscale Chromatography for Ultrasensitive Targeted Mass Spectrometry. Methods Mol Biol, 2022Cifani P, Li Z, Luo D, Grivainis M, Intlekofer AM, Fenyö D, Kentsis A. Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics. J Proteome Research, 2021Takao S, Forbes L, Uni M, Cheng S, Pineda JMB, Tarumoto Y, Cifani P, Minuesa G, Chen C, Kharas MG, Bradley RK, Vakoc CR, Koche RP, Kentsis A. Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia. eLife, 2021Kentsis A. Why do young people get cancer? Pediatr Blood Cancer, 2020Kentsis A, Frank SA. Developmental Mutators and Early Onset Cancer. Front Pediatr, 2020Ortiz MV, Ahmed S, Burns M, Henssen AG, Hollmann TJ, MacArthur I, Gunasekera S, Gaewsky L, Bradwin G, Ryan J, Letai A, He Y, Naranjo A, Chi YY, LaQuaglia M, Heaton T, Cifani P, Dome JS, Gadd S, Perlman E, Mullen E, Steen H, Kentsis A. Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms’ tumor. JCI Insight, 2019Ser Z, Cifani P, Kentsis A. Optimized cross-linking mass spectrometry for in situ interaction proteomics. J Proteome Research, 2019McNeer NA, Philip J, Geiger H, Ries RE, Lavallée VP, Walsh M, Shah M, Arora K, Emde AK, Robine N, Alonzo TA, Kolb EA, Gamis AS, Smith M, Gerhard DS, Guidry-Auvil J, Meshinchi S, Kentsis A. Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia. Leukemia, 2018Cifani P, Dhabaria A, Chen Z, Yoshimi A, Kawaler E, Abdel-Wahab O, Poirier JT, Kentsis A. ProteomeGenerator: A framework for comprehensive proteomics based on de novo transcriptome assembly and high-accuracy peptide mass spectral matching. J Proteome Research, 2018Gutierrez A & Kentsis A. Acute myeloid/T-lymphoblastic leukaemia (AMTL): a distinct category of acute leukaemias with common pathogenesis in need of improved therapy. Br J Haematol, 2018Cifani P, Kentsis A. High sensitivity quantitative proteomics using automated multidimensional nano-flow chromatography and accumulated ion monitoring on quadrupole-Orbitrap-linear ion trap mass spectrometer. Mol Cell Proteomics, 2017Henssen A, Koche R, Zhuang J, Jiang E, Reed C, Eisenberg A, Still E, Rodriguez-Fos E, Gonzalez S, Puiggros M, Blackford A, Mason C, De Stanchina E, Gonen M, Emde A, Shah M, Arora K, Reeves C, Socci N, Perlman E, Antonescu C, Roberts C, Steen H, Mullen E, Jackson S, Torrents D, Weng Z, Armstrong S, Kentsis A. PGBD5 promotes site-specific oncogenic mutations in human tumors. Nature Genetics, 2017Cifani P, Shakiba M, Chhangawala S, Kentsis A. ProteoModlR for functional proteomics. BMC Bioinformatics, 2017Brown FC, Cifani P, Drill E, He J, Still E, Zhong S, Balasubramanian S, Pavlick D, Yilmazel B, Knapp KM, Alonzo TA, Meshinchi S, Stone RM, Kornblau SM, Marcucci G, Gamis AS, Byrd JC, Gonen M, Levine RL, Kentsis A. Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia. Br J Haematol, 2017Cifani P, Kentsis A. High Sensitivity Quantitative Proteomics Using Automated Multidimensional Nano-flow Chromatography and Accumulated Ion Monitoring on Quadrupole-Orbitrap-Linear Ion Trap Mass Spectrometer. Mol Cell Proteomics, 2017Henssen AG, Jiang E, Zhuang J, Pinello L, Socci ND, Koche R, Gonen M, Villasante CM, Armstrong SA, Bauer DE, Weng Z, Kentsis A. Forward genetic screen of human transposase genomic rearrangements. BMC Genomics, 2016Ortiz MV, Kobos R, Walsh M, Slotkin EK, Roberts S, Berger MF, Hameed M, Solit D, Ladanyi M, Shukla N, Kentsis A. Integrating Genomics Into Clinical Pediatric Oncology Using the Molecular Tumor Board at the Memorial Sloan Kettering Cancer Center. Pediatr Blood Cancer, 2016Henssen AG, Henaff E, Jiang E, Eisenberg AR, Carson JR, Villasante CM, Ray M, Still E, Burns M, Gandara J, Feschotte C, Mason CE, Kentsis A. Genomic DNA transposition induced by human PGBD5. eLife, 2015Dhabaria A, Cifani P, Reed C, Steen H, Kentsis A. A High-Efficiency Cellular Extraction System for Biological Proteomics. J Proteome Res, 2015McGee SF, Kornblau SM, Qiu Y, Look AT, Zhang N, Yoo SY, Coombes KR, Kentsis A. Biological properties of ligand-dependent activation of the MET receptor kinase in acute myeloid leukemia. Leukemia, 2015Mansour MR, Reed C, Eisenberg AR, Tseng JC, Twizere JC, Daakour S, Yoda A, Rodig SJ, Tal N, Shochat C, Berezovskaya A, DeAngelo DJ, Sallan SE, Weinstock DM, Izraeli S, Kung AL, Kentsis A, Look AT. Cite Targeting oncogenic interleukin-7 receptor signaling with N-acetylcysteine in T cell acute lymphoblastic leukaemia. Br J Haematol, 2015 Book traversal links for The Alex Kentsis Lab Previous Featured News Next Open Positions