Research ArticlesBandyopadhyay U, Todorova P, Pavlova NN, Tada Y, Thompson CB, Finley L, Overholtzer M. (2022) Leucine retention in lysosomes is regulated by starvation. Proc Natl Acad Sci USA. Feb 8;119(6):e2114912119.Hayashi A, Fan J, Chen R, Ho YJ, Makohon-Moore AP, Lecomte N, Zhong Y, Hong J, Huang J, Sakamoto H, Attiyeh MA, Kohutek ZA, Zhang L, Boumiza A, Kappagantula R, Baez P, Bai J, Lisi M, Chadalavada K, Melchor JP, Wong W, Nanjangud GJ, Basturk O, O’Reilly EM, Kimstra DS, Hruban RH, Wood LD, Overholtzer M, Iacobuzio-Donahue CA (2022) A unifying paradigm for transcriptional heterogeneity and squamous features in pancreatic ductal adenocarcinoma. Nat Cancer. Feb 2.Riegman M, Sagie L, Galed C, Levin T, Steinberg N, Dixon SJ, Wiesner U, Brandbury MS, Niethammer P, Zaritsky A, Overholtzer M. (2020) Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture. Nat Cell Biol. Sep 22; (9):1042-1048.Katikaneni A, Jelcic M, Gerlach GF, Ma Y, Overholtzer M, Niethammer P. (2020) Lipid peroxidation regulates long-range wound detection through 5-lipoxygenase in zebrafish. Nat Cell Biol. Sep 22;(9):1049-1055.Lee C, Lamech L, Johns E, Overholtzer M. (2020) Selective Lysosome Membrane Turnover is Induced by Nutrient Starvation. Dev Cell. Aug 31;S1534-5807(20)30666-3.Hamann JC, Surcel A, Chen R, Teragawa C, Albeck JG, Robinson DN, Overholtzer M. (2017) Entosis Is Induced by Glucose Starvation. Cell Rep. Jul 5;20(1):201-210.Kim SE, Zhang L, Ma K, Riegman M, Chen F, Ingold I, Conrad M, Gao M, Jiang X, Monette S, Mohan P, Chen F, Gonen M, Zanzonico P, Quinn T, Wiesner U, Bradbury MS, Overholtzer M. (2016) Ultrasmall Nanoparticles Induce Ferroptosis of Nutrient-Deprived Cancer Cells and Suppress Tumor Growth. Nat Nanotechnol. Nov;11(11):977-985.Krishna S, Palm W, Lee Y, Yang W, Xu H, Florey O, Thompson CB, Overholtzer M. (2016) PIKfyve regulates vacuole maturation and nutrient recovery following engulfment. Dev Cell. Sep 12;38(5):536-47.Sun Q, Luo T, Ren Y, Florey O, Shirasawa S, Sasazuki T, Robinson DN, Overholtzer M. (2014) Competition between human cells by entosis. Cell Res. Nov;24(11):1299-310.Sun Q, Cibas ES, Huang H, Hodgson L, Overholtzer M. (2014) Induction of entosis by epithelial cadherin expression. Cell Res. Nov;24(11):1288-98.Krajcovic M, Krishna S, Akkari L, Joyce JA, Overholtzer M. (2013) mTOR regulates phagosome and entotic vacuole fission. Mol Biol Cell. Dec 24(23): 3736-45.Review ArticlesHamann JC, Overholtzer M. (2017) Entosis enables a population response to starvation. Oncotarget. Aug 9;8(35):57934-57935.Kim SE, Overholtzer M. (2013) Autophagy proteins regulate cell engulfment mechanisms that participate in cancer. (Review) Semin Cancer Biol. 2013 May 30. Book traversal links for The Michael Overholtzer Lab Previous Featured News Next Open Positions