Cancer Biology & Genetics Program
The Scott Lowe Lab
Research
![Scott Lowe](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/6821/person/lowe_180423_05_1200x800_0.jpg?h=10d202d3)
About the Scott Lowe Lab
Cancer biologist Scott Lowe uses genetically engineered mouse models to study how the genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response, and create molecular vulnerabilities that may be targeted therapeutically.
Cancer arises through an evolutionary process whereby normal cells acquire mutations that erode growth controls. Still, cancer is not an inevitable consequence of mutation, but is kept in check by intrinsic tumor-suppressor programs activated in damaged cells. We study such programs to reveal, and ultimately exploit, the strategies nature uses to combat cancer.
Our early studies focused on cell-intrinsic programs that prevent tumorigenesis (e.g., apoptosis, senescence), and have broadened to cell-extrinsic mechanisms (e.g., immune surveillance). New areas of interest include how tumor-suppressive programs are blunted by environmental factors known to increase cancer incidence (e.g., obesity, aging) and how excessive activation of tumor-suppressive programs (e.g., senescence) can harm function of normal tissue. To gain a mechanistic understanding of these phenomena, we apply mouse models in which cancer arises in an intact tissue ecosystem, which is a long-standing strength of our program. Our affiliation with Memorial Sloan Kettering Cancer Center enables us to probe human systems as well.
Another major goal is to harness our knowledge of tumor suppression therapeutically. We and others have shown that reengaging tumor-suppressive programs in established cancer cells can coordinate tumor regression through both cell-intrinsic and cell-extrinsic components (1-5), so these programs represent attractive strategies for tumor control. With Michel Sadelain, we have also developed a cell therapy approach to remove excessive senescent cells from tissues (6); this therapy may have beneficial effects on cancer and non-cancer pathologies. Advancing these concepts are major goals of our current research.
Research Projects
![Lowe Lab](https://www.mskcc.org/sites/default/files/node/6821/images/lowe-lab-group-220518-3_0.jpg)
Featured News
![Dana Pe'er and Scott Lowe](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/274811/main_image/peerlowe_1200x800.jpg)
![Postdocs Francisco “Pancho” Barriga and Kaloyan Tsanov in the lab](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/255791/main_image/machete-220908-184-rt-12x8.jpg)
![Scott Lowe](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/253071/main_image/lowe_180423_05_1200x800.jpg)
Publications Highlights
Burdziak C, Alonso-Curbelo D, Walle T, Reyes J, Barriga FM, Haviv D, Xie Y, Zhao Z, Zhao CJ, Chen HA, Chaudhary O, Masilionis I, Choo ZN, Gao V, Luan W, Wuest A, Ho YJ, Wei Y, Quail DF, Koche R, Mazutis L, Chaligné R, Nawy T, Lowe SW, Pe’er D.Science. 2023 May 12;380(6645):eadd5327. doi: 10.1126/science.add5327. Epub 2023 May 12.PMID: 37167403
Chen HA, Ho YJ, Mezzadra R, Adrover JM, Smolkin R, Zhu C, Woess K, Bernstein N, Schmitt G, Fong L, Luan W, Wuest A, Tian S, Li X, Broderick C, Hendrickson RC, Egeblad M, Chen Z, Alonso-Curbelo D, Lowe SW.Cancer Discov. 2023 Feb 6;13(2):432-453. doi: 10.1158/2159-8290.CD-22-0528.PMID: 36302222 Free PMC article.
People
![Scott Lowe](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/6821/person/lowe_180423_05_1200x800_0.jpg?h=10d202d3)
Scott W. Lowe, PhD
Chair, Cancer Biology & Genetics Program, SKI; Chair, Geoffrey Beene Cancer Research Center; Investigator, Howard Hughes Medical Institute
- PhD, Massachusetts Institute of Technology
- [email protected]
- Email Address
- 646-888-3342
- Office Phone
- Download CV
- PDF File
Members
![Valentin Barthet](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/239953/main_image/barthet-valentin-220119-021-rt-1200x800.jpg?h=10d202d3)
- PhD, Cancer Research UK Beatson Institute, University of Glasgow, Scotland, United Kingdom
- 646-888-3340
- Lab Phone
![Lynn Boss, MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141709/3x2/boss_180509_10_1200x800.jpg?h=10d202d3)
- MS, Stony Brook University
![Caroline Broderick](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227671/main_image/broderick-caroline_210610_02-1200x800.jpg?h=10d202d3)
- BS, University of California, Santa Barbara, CA
- 646-888-3340
- Lab Phone
![Andrea Chaikovsky](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/239950/main_image/chaikovsky-andrea-220119-008-rt-1200x800.jpg?h=10d202d3)
- PhD, Stanford University, Stanford, CA
- 646-888-3340
- Lab Phone
![Almudena Chaves Perez](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227338/main_image/chaves-perez-almudena_210610_06-1200x800.jpg?h=10d202d3)
- PhD, Autonomous University of Madrid, Spain
- 646-888-3340
- Lab Phone
![Aveline Filliol](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/282481/main_image/filliol-aveline-230809-01_rt_1200x800.jpg)
- PhD, University of Rennes 1
- 646-888-3340
- Lab Phone
![Clemens Hinterleitner](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/239947/main_image/hinterleitner-clemens-220119-009-rt-1200x800.jpg?h=10d202d3)
- MD, Johannes-Gutenberg-University, School of Medicine, Mainz, Germany
- 646-888-3340
- Lab Phone
![Yu-Jui (Ray) Ho, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/147955/3x2/ho_180423_05_1200x800.jpg?h=10d202d3)
- PhD, Cold Spring Harbor Laboratory, New York
- 646-888-3340
- Lab Phone
![Margaret Kennedy](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227344/main_image/kennedy-margaret_210610_05-1200x800.jpg?h=10d202d3)
- BS, The College of New Jersey, Ewing, NJ
- 646-888-3340
- Lab Phone
![Wei Luan, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/127336/main_image/luan-wei_210610_04-1200x800.jpg?h=10d202d3)
- MD, Capital University of Medical Sciences (China)
- 646-888-3340
- Lab Phone
![Domhnall McHugh, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/256826/main_image/mc-hugh-domhnall-220518-09_rt_1200x800.jpg?h=10d202d3)
- PhD, Imperial College London, United Kingdom
- 646-888-3340
- Lab Phone
![Riccardo Mezzadra](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/165787/3x2/mezzadra_181017_20_1200x800.jpg?h=10d202d3)
- PhD, Netherlands Cancer Institute (Netherlands)
- 646-888-3340
- Lab Phone
![Nalin Ratnayeke](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/282341/main_image/ratnayeke-nalin-230809-04_rt_1200x1200.jpg?h=cd2a7045)
- Stanford University
- 646-888-3342
- Office Phone
![José Reyes](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/171916/3x2/reyes-jose_190206_08_1200x800.jpg?h=10d202d3)
- PhD, Harvard University, Cambridge, MA
- 646-888-3340
- Lab Phone
![Corinne L. Rodriguez](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141691/main_image/rodriguez-corinne-230809-07_rt_1200x1200_0.jpg?h=cd2a7045)
![Exequiel Sisso](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/246598/main_image/sisso-exequiel-220518-01_1200x800.jpg?h=10d202d3)
![Sha Tian, MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18983/3x2/tian_180509_02_1200x800.jpg?h=10d202d3)
- MS, University of Turku (Finland)
- 646-888-3340
- Lab Phone
![Kaloyan Tsanov, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/145861/3x2/tsanov_180509_02_1200x800.jpg?h=10d202d3)
- PhD, Harvard University, Cambridge, MA
- 646-888-3340
- Lab Phone
![Zeda Zhang](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227335/main_image/zhang-zeda_210610_02-1200x800.jpg?h=10d202d3)
- PhD, Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY
- 646-888-3340
- Lab Phone
![Changyu Zhu](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/181696/3x2/zhu-changyu_190830_10_1200x800.jpg?h=10d202d3)
- PhD, Columbia University, New York, NY
- 646-888-3340
- Lab Phone
![Valentin Barthet](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/239953/main_image/barthet-valentin-220119-021-rt-1200x800.jpg?h=10d202d3)
Postdoctoral Researcher
![Lynn Boss, MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141709/3x2/boss_180509_10_1200x800.jpg?h=10d202d3)
Administrative Coordinator
![Caroline Broderick](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227671/main_image/broderick-caroline_210610_02-1200x800.jpg?h=10d202d3)
Graduate Student
![Andrea Chaikovsky](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/239950/main_image/chaikovsky-andrea-220119-008-rt-1200x800.jpg?h=10d202d3)
Postdoctoral Researcher
![Almudena Chaves Perez](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227338/main_image/chaves-perez-almudena_210610_06-1200x800.jpg?h=10d202d3)
Postdoctoral Researcher
![Isabella Del Priore, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/256146/main_image/del-priore-isabella-220518-10_1200x800.jpg?h=10d202d3)
Graduate Student
![Xin Fang](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/240499/main_image/fang-xin-220119-005-rt-1200x800.jpg?h=10d202d3)
Research Technician
![Aveline Filliol](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/282481/main_image/filliol-aveline-230809-01_rt_1200x800.jpg)
Lead Program Manager
![Hailey V. Goldberg](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/286291/main_image/goldberg-hailey-230926-003_rt_1200x1200.jpg?h=cd2a7045)
Graduate Student
![Clemens Hinterleitner](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/239947/main_image/hinterleitner-clemens-220119-009-rt-1200x800.jpg?h=10d202d3)
Postdoctoral Researcher
![Yu-Jui (Ray) Ho, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/147955/3x2/ho_180423_05_1200x800.jpg?h=10d202d3)
Computational Biologist
![Margaret Kennedy](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227344/main_image/kennedy-margaret_210610_05-1200x800.jpg?h=10d202d3)
Graduate Student
![Wei Luan, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/127336/main_image/luan-wei_210610_04-1200x800.jpg?h=10d202d3)
Senior Research Technician
![Domhnall McHugh, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/256826/main_image/mc-hugh-domhnall-220518-09_rt_1200x800.jpg?h=10d202d3)
Postdoctoral Researcher
![Riccardo Mezzadra](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/165787/3x2/mezzadra_181017_20_1200x800.jpg?h=10d202d3)
Postdoctoral Researcher
![Nalin Ratnayeke](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/282341/main_image/ratnayeke-nalin-230809-04_rt_1200x1200.jpg?h=cd2a7045)
Postdoctoral Researcher
![José Reyes](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/171916/3x2/reyes-jose_190206_08_1200x800.jpg?h=10d202d3)
Postdoctoral Researcher
![Corinne L. Rodriguez](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141691/main_image/rodriguez-corinne-230809-07_rt_1200x1200_0.jpg?h=cd2a7045)
Assistant to Chair
![Janelle Simon, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18987/3x2/simon_180509_05_1200x800.jpg?h=10d202d3)
Mouse Colony Manager
![Exequiel Sisso](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/246598/main_image/sisso-exequiel-220518-01_1200x800.jpg?h=10d202d3)
Research Technician
![Sha Tian, MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18983/3x2/tian_180509_02_1200x800.jpg?h=10d202d3)
Senior Research Technician
![Anne Trumble-Koncelik](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/26842/3x2/trumble-koncelik_180425_01_1200x800.jpg?h=10d202d3)
Lab Manager
![Kaloyan Tsanov, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/145861/3x2/tsanov_180509_02_1200x800.jpg?h=10d202d3)
Postdoctoral Researcher
![Zeda Zhang](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227335/main_image/zhang-zeda_210610_02-1200x800.jpg?h=10d202d3)
Postdoctoral Researcher
![Changyu Zhu](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/181696/3x2/zhu-changyu_190830_10_1200x800.jpg?h=10d202d3)
Postdoctoral Researcher
![S Millman, MD PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141910/3x2/millman_180423_07_1200x800.jpg?h=10d202d3)
- MD PhD, NYU School of Medicine
- Residency (Internal Medicine), Massachusetts General Hospital
- Fellowship (Medical Oncology), MSKCC
![Direna Alonso Curbelo, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/26047/3x2/alonso_curbelo_180509_27_1200x800.jpg?h=10d202d3)
- PhD, Centro Nacional de Investigaciones Oncológicas [CNIO] (Spain)
![Francisco Barriga, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141673/3x2/barriga_180509_04_1200x800.jpg?h=10d202d3)
- PhD, Universitat Pompeu Fabra and Institute for Research in Biomedicine [IRB] Barcelona (Spain)
![Iris Appelmann, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18881/image/appelmann-iris.jpg?h=10d202d3)
- MD, Westphalian Wilhelms University (Germany)
![Corina Amor Vegas](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/142897/3x2/amor_vegas_181017_02_1200x800.jpg?h=10d202d3)
- MD, Universidad Complutense de Madrid (Spain)
- PhD, Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY
![Ana Banito, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18982/image/anablabphoto.jpg?h=10d202d3)
- PhD, Medical Research Council, Clinical Sciences Centre, Imperial College London (UK)
![Benedikt Bosbach, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/3731/image/110629-besmer-004.jpg?h=10d202d3)
- PhD, University of Konstanz (Germany)
![Chi-Chao Chen, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18979/3x2/chen_chi-chao_180423_05_1200x800.jpg?h=10d202d3)
- PhD, Weill Cornell Medical College, New York, NY
- MD, National Taiwan University (Taiwan)
![Hsuan-An Chen](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/106698/3x2/chen_180423_07_1200x800.jpg?h=10d202d3)
- BS, National Taiwan University (Taiwan)
- PhD, Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY
![Chong Chen, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18884/image/chen-chong.jpg?h=10d202d3)
- PhD, University of Michigan, Ann Arbor, MI
![Lukas Dow, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18875/image/dow-lukas.jpg?h=10d202d3)
- PhD, University of Melbourne (Australia)
![Saya Ebbesen, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18974/image/ebbesen-saya.jpg?h=10d202d3)
- PhD, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, NY
![Katerina Hatzi, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141682/3x2/chatzi_180423_02_1200x800.jpg?h=10d202d3)
- PhD, Weill Cornell Medical College, New York, NY
![Shauna Houlihan, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/126778/3x2/houlihan_180509_14_1200x800.jpg?h=10d202d3)
- PhD, Northwestern University Feinberg School of Medicine, Chicago, IL
![Grace Xiang Li, MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/113620/3x2/li_180423_12_1200x800.jpg?h=10d202d3)
- MS, The Ohio State University, Columbus, OH
- PhD, Weill Cornell Medical College, New York, NY
![Chun-Hao Huang, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18978/image/huang-chun-hao-2.jpg?h=10d202d3)
- PhD, Weill Cornell Medical College, New York, NY
![Edward Kastenhuber, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/13052/3x2/kastenhuber_180423_04_1200x800.jpg?h=10d202d3)
- PhD, Gerstner Sloan Kettering Graduate School, New York, NY
![Thomas Kitzing, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18879/image/kitzing-thomas-m.jpg?h=10d202d3)
- PhD, University of Heidelberg (Germany)
![Josef Leibold, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/113614/3x2/leibold_180423_05_1200x800.jpg?h=10d202d3)
- MD, University of Tübingen (Germany)
![Kiki Yu Liu, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18882/image/liu-kiki.jpg?h=10d202d3)
- PhD, Albert Einstein College of Medicine, New York, NY
![Geulah Livshits, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18980/image/livshits-geulah.jpg?h=10d202d3)
- PhD, The Rockefeller University, New York, NY
![Bryan Ngo](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227677/main_image/ngo-bryan_210610_08-1200x800.jpg?h=10d202d3)
- PhD, Weill Cornell Medical College, New York, NY
![Stella Paffenholz, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/125503/3x2/paffenholz_180423_09_1200x800.jpg?h=10d202d3)
- PhD, Gerstner Sloan Kettering Graduate School, New York, NY
![Francisco Sánchez-Rivera, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/126775/3x2/sanchez-rivera_180423_09_1200x800.jpg?h=10d202d3)
- PhD, Massachusetts Institute of Technology, Cambridge, MA
![Evangelia Loizou, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/34659/3x2/loizou_180423_12_1200x800.jpg?h=10d202d3)
- PhD, Weill Cornell Medical College, New York, NY
![Amaia Lujambio, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18880/image/lujambio-goizueta-amaia.jpg?h=10d202d3)
- PhD, Centro Nacional de Investigaciones Oncológicas [CNIO] (Spain)
![Eusebio Manchado Robles, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/19570/image/manchado-robles-eusebio-chebi.jpg?h=10d202d3)
- PhD, Centro Nacional de Investigaciones Oncológicas [CNIO] (Spain)
![Allison Mayle, Postdoctoral Researcher](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/126769/3x2/mayle_180423_06_1200x800.jpg?h=10d202d3)
- PhD, Baylor College of Medicine, Houston, TX
![Ozlem Mert, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18976/image/mert-ozlem2.jpg?h=10d202d3)
- PhD, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, NY
![Cornelius Miething, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18877/image/miething-cornelius.jpg?h=10d202d3)
- PhD, University of Frankfurt (Germany)
![John P. Morris IV, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18981/3x2/morris_180423_07_1200x800.jpg?h=10d202d3)
- PhD, University of California, San Francisco, CA
![Kevin P. O'Rourke, MD, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/26075/3x2/kevin-o-rourke-headshot-full_3x2.jpg?h=10d202d3)
- MD-PhD, Weill Cornell Medical College, New York, NY
![Cory Rillahan, MD, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/19804/image/rillihan-cory.jpg?h=a339a150)
- PhD, The Scripps Research Institute, La Jolla, CA
![Marcus Ruscetti, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/113617/3x2/ruscetti_180509_05_1200x800.jpg?h=10d202d3)
- PhD, University of California, Los Angeles, CA
![Anna Saborowski, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18883/image/saborowski-anna.jpg?h=10d202d3)
- MD, Hannover Medical School (Germany)
![Michael Saborowski, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18876/image/saborowski-michael.jpg?h=10d202d3)
- MD, University of Leipzig (Germany)
![Charles J Sherr](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141688/3x2/sherr_charles-1200-by-800.jpg?h=10d202d3)
![Nilgun Tasdemir, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18975/image/tasdemir-nilgun.jpg?h=10d202d3)
- PhD, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, NY
![Darjus Tschaharganeh, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/19806/image/tschaharganeh-darjus.jpg?h=10d202d3)
- MD, RWTH Aachen (Germany)
![Susann Weissmueller, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18977/image/susi.jpg?h=10d202d3)
- PhD, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, NY
![Zhen Zhao, MD PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18878/image/zhao-zhen-2.jpg?h=10d202d3)
- MD, Medical University of China (China)
- PhD, Stony Brook University, New York
![Sarah Ackermann](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18872/3x2/ackermann_180509_03_1200x800.jpg?h=10d202d3)
- BS, Carnegie Mellon University, Pittsburgh, PA
![James H. Ahn, MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18986/image/ahn-james.jpg?h=10d202d3)
- MS, New York University
![Erica Anderson, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141979/3x2/erica-1200-x-800_0.jpg?h=10d202d3)
- BS, University of Connecticut
![Mayerlin Chalarca](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/126610/3x2/chalarca_180509_07_1200x800.jpg?h=10d202d3)
- AALAS Technician Certification
![Jonathan Fisher, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/24931/image/jonathan.jpg?h=10d202d3)
- BS, Yale University
![Danielle Grace, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18984/image/grace-danielle.jpg?h=10d202d3)
- BS, Molloy College
![Fernanda Luna, BA](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141676/3x2/fernanda-1200-by-800.jpg?h=3732344e)
- BA, City College of New York
![Jamie Plevy, BSE MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18873/image/jamie-plevy.jpg?h=10d202d3)
- MS, New York University
- BSE, University of Pennsylvania
![Katarzyna Rybczyk](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/171805/3x2/rybczyk-_katarzyna_190206_05_1200x800-1.jpg?h=10d202d3)
- BS, Binghamton University
![Aditya S. Shroff, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18985/image/shroff-adi.jpg?h=10d202d3)
- BS, Stony Brook University
![Meredith Taylor, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/26920/image/merri.jpg?h=10d202d3)
- BS, Fairleigh Dickinson University
![Anahi Tehuitzil](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/160324/3x2/tehuitzil_181017_13_1200x800.jpg?h=10d202d3)
- BA, Hunter College
![Vincent Tem](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227341/main_image/tem-vincent_210610_04-1200x800.jpg?h=10d202d3)
- MSc Oxon, University of Oxford (England)
![Alexandra Wuest](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/171919/3x2/wuest-alexandra_190206_04_1200x800.jpg?h=10d202d3)
- BS, University of Cincinnati
Lab Alumni
![S Millman, MD PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141910/3x2/millman_180423_07_1200x800.jpg?h=10d202d3)
Instructor in Medicine
![Direna Alonso Curbelo, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/26047/3x2/alonso_curbelo_180509_27_1200x800.jpg?h=10d202d3)
Junior Group Leader, Cancer Science, IRB Barcelona, Spain
![Francisco Barriga, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141673/3x2/barriga_180509_04_1200x800.jpg?h=10d202d3)
Group Leader - Cancer Genome Engineering Lab Vall D´Hebron Institute of Oncology (VHIO)
![Iris Appelmann, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18881/image/appelmann-iris.jpg?h=10d202d3)
Physician, University Hospital RWTH Aachen, Germany
![Corina Amor Vegas](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/142897/3x2/amor_vegas_181017_02_1200x800.jpg?h=10d202d3)
CSHL Independent Fellow at Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
![Ana Banito, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18982/image/anablabphoto.jpg?h=10d202d3)
Group Leader, German Cancer Research Center (DKFZ), Heidelberg, Germany
![Benedikt Bosbach, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/3731/image/110629-besmer-004.jpg?h=10d202d3)
Principal Scientist, CTI, Pfizer Research, New York
![Chi-Chao Chen, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18979/3x2/chen_chi-chao_180423_05_1200x800.jpg?h=10d202d3)
Data Scientist, Agios Pharmaceuticals, Inc., Cambridge, MA
![Hsuan-An Chen](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/106698/3x2/chen_180423_07_1200x800.jpg?h=10d202d3)
Postdoctoral Fellow at Rockefeller University, New York, NY
![Chong Chen, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18884/image/chen-chong.jpg?h=10d202d3)
Professor, Sichuan University, Sichuan, China
![Lukas Dow, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18875/image/dow-lukas.jpg?h=10d202d3)
Assistant Professor, Weill Cornell Medical College, New York, NY
![Saya Ebbesen, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18974/image/ebbesen-saya.jpg?h=10d202d3)
Director, Medical & Scientific Strategy, BluPrint Oncology, London
![Katerina Hatzi, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141682/3x2/chatzi_180423_02_1200x800.jpg?h=10d202d3)
Senior Scientist, Oncology Biomarker Development, Genentech, San Francisco, CA
![Shauna Houlihan, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/126778/3x2/houlihan_180509_14_1200x800.jpg?h=10d202d3)
Associate Director, Liver Research, Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY
![Grace Xiang Li, MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/113620/3x2/li_180423_12_1200x800.jpg?h=10d202d3)
Postdoctoral Fellow, Harvard University, Cambridge, MA
![Chun-Hao Huang, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18978/image/huang-chun-hao-2.jpg?h=10d202d3)
Co-Founder & CEO, Algen Biotechnologies, San Francisco, CA
![Edward Kastenhuber, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/13052/3x2/kastenhuber_180423_04_1200x800.jpg?h=10d202d3)
Postdoctoral Associate, Weill Cornell Medicine, New York, NY
![Thomas Kitzing, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18879/image/kitzing-thomas-m.jpg?h=10d202d3)
Senior Research Scientist, Philipps University of Marburg, Institute of Pharmacology, Germany
![Josef Leibold, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/113614/3x2/leibold_180423_05_1200x800.jpg?h=10d202d3)
Group Leader, University of Tübingen, Germany
![Kiki Yu Liu, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18882/image/liu-kiki.jpg?h=10d202d3)
Professor, Sichuan University, Sichuan, China
![Geulah Livshits, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18980/image/livshits-geulah.jpg?h=10d202d3)
Senior Research Analyst, Biotechnology and Pharmaceuticals, Chardan Capital Markets LLC, New York, NY
![Bryan Ngo](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227677/main_image/ngo-bryan_210610_08-1200x800.jpg?h=10d202d3)
Group Leader, Altos Labs, San Francisco, CA
![Stella Paffenholz, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/125503/3x2/paffenholz_180423_09_1200x800.jpg?h=10d202d3)
Analyst, Nexttech, Boston, MA
![Francisco Sánchez-Rivera, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/126775/3x2/sanchez-rivera_180423_09_1200x800.jpg?h=10d202d3)
Assistant Professor of Biology, Massachusetts Institute of Technology, Cambridge, MA
![Evangelia Loizou, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/34659/3x2/loizou_180423_12_1200x800.jpg?h=10d202d3)
Senior Research Associate, Intelligencia, New York, NY
![Amaia Lujambio, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18880/image/lujambio-goizueta-amaia.jpg?h=10d202d3)
Associate Professor, Mount Sinai School of Medicine, New York, NY
![Eusebio Manchado Robles, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/19570/image/manchado-robles-eusebio-chebi.jpg?h=10d202d3)
Senior Principal Scientist, Novartis, Basel, Switzerland
![Allison Mayle, Postdoctoral Researcher](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/126769/3x2/mayle_180423_06_1200x800.jpg?h=10d202d3)
Assistant Director, DNALC, Cold Spring Harbor Laboratory, New York
![Ozlem Mert, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18976/image/mert-ozlem2.jpg?h=10d202d3)
Senior Scientist, Pfizer, San Francisco, CA
![Cornelius Miething, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18877/image/miething-cornelius.jpg?h=10d202d3)
Group Leader and Medical Fellow, University Medical Center Freiburg, Germany
![John P. Morris IV, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18981/3x2/morris_180423_07_1200x800.jpg?h=10d202d3)
Assistant Professor, Department of Pharmacology, University of North Carolina, Chapel Hill, NC
![Kevin P. O'Rourke, MD, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/26075/3x2/kevin-o-rourke-headshot-full_3x2.jpg?h=10d202d3)
Investments, Roivant Sciences, New York, NY
![Cory Rillahan, MD, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/19804/image/rillihan-cory.jpg?h=a339a150)
Clinical Fellow, Pediatrics, Boston Children's Hospital, Boston, MA
![Marcus Ruscetti, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/113617/3x2/ruscetti_180509_05_1200x800.jpg?h=10d202d3)
Assistant Professor, Molecular, Cell & Cancer Biology, University of Massachusetts Medical School, Worcester, MA
![Anna Saborowski, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18883/image/saborowski-anna.jpg?h=10d202d3)
Physician, Hannover Medical School, Germany
![Michael Saborowski, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18876/image/saborowski-michael.jpg?h=10d202d3)
Physician, Hannover Medical School, Germany
![Charles J Sherr](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141688/3x2/sherr_charles-1200-by-800.jpg?h=10d202d3)
Chair, Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN
![Nilgun Tasdemir, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18975/image/tasdemir-nilgun.jpg?h=10d202d3)
Senior Scientist, Functional Genomics, Target Sciences, Pfizer, New York, NY
![Darjus Tschaharganeh, MD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/19806/image/tschaharganeh-darjus.jpg?h=10d202d3)
Group Leader, German Cancer Research Center (DKFZ), Heidelberg, Germany
![Susann Weissmueller, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18977/image/susi.jpg?h=10d202d3)
Strategic Partnering Associate, Roche, Basel, Switzerland
![Zhen Zhao, MD PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18878/image/zhao-zhen-2.jpg?h=10d202d3)
Pathology Resident, The Mount Sinai Hospital, New York, NY
![Sarah Ackermann](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18872/3x2/ackermann_180509_03_1200x800.jpg?h=10d202d3)
Research Specialist, Weill Cornell Medicine, New York, NY
![James H. Ahn, MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18986/image/ahn-james.jpg?h=10d202d3)
Research Technician
![Erica Anderson, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141979/3x2/erica-1200-x-800_0.jpg?h=10d202d3)
Research Technician
![Mayerlin Chalarca](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/126610/3x2/chalarca_180509_07_1200x800.jpg?h=10d202d3)
Research Technician
![Ho-Chung Chen, MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/127333/3x2/ho-chung_3x2.jpg?h=10d202d3)
Research Technician
![Jonathan Fisher, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/24931/image/jonathan.jpg?h=10d202d3)
Research Technician
![Danielle Grace, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18984/image/grace-danielle.jpg?h=10d202d3)
Research Technician
![Fernanda Luna, BA](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/141676/3x2/fernanda-1200-by-800.jpg?h=3732344e)
Research Technician
![Jamie Plevy, BSE MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18873/image/jamie-plevy.jpg?h=10d202d3)
Research Technician
![Katarzyna Rybczyk](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/171805/3x2/rybczyk-_katarzyna_190206_05_1200x800-1.jpg?h=10d202d3)
Research Technician
![Aditya S. Shroff, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/18985/image/shroff-adi.jpg?h=10d202d3)
Research Technician
![Meredith Taylor, BS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/26920/image/merri.jpg?h=10d202d3)
Research Technician
![Anahi Tehuitzil](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/160324/3x2/tehuitzil_181017_13_1200x800.jpg?h=10d202d3)
Research Technician
![Vincent Tem](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/227341/main_image/tem-vincent_210610_04-1200x800.jpg?h=10d202d3)
Research Technician
![Alexandra Wuest](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/171919/3x2/wuest-alexandra_190206_04_1200x800.jpg?h=10d202d3)
Research Technician
![Leah Zamechek, MS](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/113623/3x2/zamechek_180423_04_1200x800.jpg?h=10d202d3)
Laboratory Manager
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs
Get in Touch
-
Lab Head Email
-
Office Phone
-
Office Fax
-
Lab Phone
Lab Resources
Scott Lowe Lab Plasmid and Animal Requests
Request plasmids through Addgene More »
For plasmids not listed on Addgene, please contact our Lab Manager, Anne Trumble-Koncelik, [email protected].
For animal requests, please contact our Mouse Colony Manager, Janelle Simon, [email protected].
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Scott W. Lowe discloses the following relationships and financial interests:
-
Blueprint Medicines
Equity; Professional Services and Activities -
Eli Lilly and Company
Equity -
Faeth Therapeutics, Inc
Equity; Professional Services and Activities (Uncompensated) -
Fate Therapeutics
Intellectual Property Rights; Professional Services and Activities -
Geras Bio Inc
Equity; Professional Services and Activities (Uncompensated)
-
Mirimus
Equity; Professional Services and Activities -
Oric Pharmaceuticals
Equity; Professional Services and Activities -
PMV Pharma
Equity; Professional Services and Activities -
Senescea Therapeutics
Equity; Intellectual Property Rights; Professional Services and Activities (Uncompensated)
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].