Simon N. Powell, MD, PhD, FRCP
Radiation Oncologist
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About Me
- Chair, Department of Radiation Oncology
- Enid A. Haupt Chair in Radiation Oncology
I am a radiation oncologist who cares for people with breast cancer. I am Chair of the Department of Radiation Oncology and have been practicing medicine for 35 years.
I see approximately 200 new patients with breast cancer each year at Memorial Sloan Kettering in Manhattan.
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When patients come to see me, they are worried about whether we can get rid of their cancer. Many patients read about their diagnosis on the internet, and the information they find can be very scary. I always make it a priority to answer all of my patients’ questions so that they feel reassured. I want them to know that they are getting the best care possible.
My research is focused on breast cancer. I have received funding from the National Institutes of Health since 1992 and am an expert in understanding how DNA repair genes like BRCA1 and BRCA2 work to fix DNA damage, as well as how a person’s genetics may influence his or her response to radiation therapy.
At MSK, we are leading the way in the use of advanced radiation techniques to ensure our patients have the best outcomes possible. For our early-stage breast cancer patients, we are using hypofractionated whole-breast irradiation. This means patients are receiving fewer total treatment sessions in a shorter time period, with a slightly higher dose given each treatment day. We also have a robust delivery system for partial breast irradiation. We now deliver treatment once per day, which helps our patients tolerate their treatment better.
I have experience treating people with recurrent or metastatic triple-negative breast cancer using radiation in combination with chemotherapy, targeted therapies, and immunotherapies.
For some people, breast cancer treatment can negatively affect the heart. At MSK, we have a program dedicated to assessing this problem. We are leaders in the field of deep inspiration breath-hold techniques, which can help lessen the cardiac side effects for our breast cancer patients. We are also using proton therapy to target tumors more precisely, which can reduce the risk of other treatment-related side effects.
I am a member of advisory boards for several cancer centers in the US and abroad, including the Netherlands Cancer Institute, Winship Cancer Institute of Emory University, University of Michigan Cancer Center, and the University of Florida Health Cancer Center.
In my free time, I enjoy theater, opera, ballet, country-specific versions of history, football, American football, and golf.
A radiation oncologist is a cancer doctor with special training in using radiation therapy (RT) to treat cancer with radiation.
My Specialties
- Radiation Oncology
- Breast Cancer
Education
- MBBS, University of London
Residencies
- Medicine - University of London Teaching Hospitals
Awards and Honors
- Castle Connolly: America’s Top Doctor (2024)
- Gold Medal Award, American Society for Therapeutic Radiology and Oncology (ASTRO, 2023)
- Top Doctors New York Metro Area, Castle Connolly (2023)
- Castle Connolly: America's Top Doctors (2023)
- Castle Connolly: New York Magazine Top Doctors (2016-2020)
- Top Doctors New York Metro Area
- Boston Top Doctors
- St. Louis Top Doctors
Fellowships
- Clinical Oncology - Royal Marsden Hospital
- Radiation Oncology - Harvard Medical School
Board Certifications
- Radiation Oncology
- Internal Medicine (UK)
Insurance Information
Understanding your insurance options is an important part of managing your cancer care. We have relationships with many common healthcare providers and plans.
In Network Coverage Type
PPO, POS, EPO, HMO
In Network Coverage Type
PPO, HMO, DSN
In Network Coverage Type
HMO, PPO
In Network Coverage Type
HMO, EPO PPO, POS
In Network Coverage Type
PPO, POS, EPO, HMO
Offers a qualified health plan from the Health Insurance Marketplace. Call Emblem to learn more.
In Network Coverage Type
PPO, HMO
In Network Coverage Type
PPO
In Network Coverage Type
HMO, EPO
Offers a qualified health plan from the Health Insurance Marketplace. Call Fidelis to learn more.
In Network Coverage Type
EPO, HMO, PPO, POS
Offers a qualified health plan from the Health Insurance Marketplace. Call Healthfirst to learn more.
In Network Coverage Type
HMO
In Network Coverage Type
PPO
In Network Coverage Type
EPO
In Network Coverage Type
EPO
In Network Coverage Type
Federal Government
In Network Coverage Type
PPO, POS, EPO, HMO
In Network Coverage Type
State Government
Don't see your carrier or plan? We can help you understand your coverage.
If you don't have health insurance or are worried that your care may not be fully covered, our financial assistance programs may be able to help.
If you have questions about insurance, call us at 646-497-9176.
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New Patients
Current Patients
Contact and Location
Dr. Powell sees patients at one location.
Looking to see a doctor at a different location? See all MSK locations.
Colleagues
Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.
See all Radiation Oncology doctors
See all External Beam Radiotherapy Service, Manhattan doctors
Clinical Trials
- Clinical Trials Co-Investigated by Dr. Powell
- A Phase II Study of Radiation Therapy with Pembrolizumab Immunotherapy and Olaparib in Women with Triple-Negative Breast Cancer
- A Phase II Study of Three-Day Partial Breast Radiation Therapy in Women with Breast Cancer
- A Study Assessing a Shortened Radiation Therapy Schedule in People Who Had a Mastectomy for Early Breast Cancer
- A Study Assessing the Addition of Pembrolizumab Immunotherapy and Radiation Therapy to Standard Chemotherapy Before Surgery in People with Breast Cancer
Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.
You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.
Search clinical trialsResearch and Publications
My research is focused on breast cancer. I have received funding from the National Institutes of Health since 1992 and am an expert in understanding how DNA repair genes like BRCA1 and BRCA2 work to fix DNA damage, as well as how a person’s genetics may influence his or her response to radiation therapy.
Visit PubMed for a full listing of Dr. Powell’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.
See all on PubMedPatient Reviews
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Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Simon N. Powell discloses the following relationships and financial interests:
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AstraZeneca
Professional Services and Activities -
PharmaPier US LLC
Professional Services and Activities (Uncompensated)
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Rain Therapeutics Inc.
Professional Services and Activities -
Varian Medical Systems
Professional Services and Activities
If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.
The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].