Tobias M. Hohl, MD, PhD
Infectious Diseases Specialist
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About Me
- Chief, Infectious Diseases Service
I am an attending physician on the inpatient Infectious Diseases Service. My clinical practice focuses on bacterial, viral, parasitic, and fungal infections in highly immunocompromised patients, in particular patients with cancers of the blood and lymph nodes and in bone marrow transplant recipients.
I have a specific interest in the prevention, diagnosis, and treatment of opportunistic fungal infections, including pulmonary and disseminated disease caused by Aspergillus, Rhizopus, Mucor, Cryptococcus, and Pneumocystis species as well as mucosal and systemic disease caused by Candida species.
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Beyond my clinical activities, I oversee a laboratory-based research program that studies the development of effective immune responses to pathogenic fungi. I hold a joint appointment in the Immunology Program of the Sloan Kettering Institute and am a faculty member in the Gerstner Sloan Kettering Graduate School of Biomedical Sciences at Memorial Sloan Kettering as well as in the Microbial Pathogenesis Program at Weill Cornell Graduate School.
My laboratory research focuses on understanding how cells of the immune system recognize opportunistic fungi and mount sterilizing immune responses to this class of microbes. Our work defines how immune and non-immune cells in the lung cooperate to clear infectious conidia (spores) from the ubiquitous mold Aspergillus fumigatus and prevent the formation of tissue-invasive hyphae. We have developed fluorescence-based tools to monitor conidial uptake and killing by infection-fighting cells in the lung and harness this technology in animal models of fungal challenge to reconstruct the molecular and cellular events required for effective immunity.
We have made contributions to understanding immune recognition of A. fumigatus via host C-type lectin receptor signaling, the transport of A. fumigatus to lung-draining lymph nodes for adaptive antifungal immune responses, the role of lung epithelial cells in recruiting neutrophils to infected airways, and the role of monocytes in innate and adaptive antifungal immunity. An emerging direction in the laboratory relates to the role of endogenous fungal communities (mycobiome) in mediating immune homeostasis. Our work seeks to understand how fungi interact with the immune system and how these interactions shape human disease and immune function.
An infectious diseases specialist is a doctor with special training in diseases caused by microorganisms (bacteria, fungi, parasites, and viruses).
My Specialties
- Infections in Patients with Cancer
Education
- MD, PhD, Weill Cornell Medical College
Residencies
- NewYork-Presbyterian Hospital/Weill Cornell Medical Center
Awards and Honors
- Fellow of the American Association for the Advancement of Science (AAAS, 2022)
Fellowships
- Memorial Sloan Kettering Cancer Center
Board Certifications
- Internal Medicine
- Infectious Disease
Insurance Information
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PPO, HMO
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HMO, EPO
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Contact and Location
Dr. Hohl sees patients at two locations.
Looking to see a doctor at a different location? See all MSK locations.
Colleagues
Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.
Clinical Trials
Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.
You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.
Search clinical trialsResearch and Publications
Visit PubMed for a full listing of Dr. Hohl’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.
See all on PubMedPatient Reviews
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Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Tobias M. Hohl discloses the following relationships and financial interests:
No disclosures meeting criteria for time period
If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.
The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.
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