This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
Brand Names: US
Spevigo
Brand Names: Canada
Spevigo
What is this drug used for?
- It is used to treat a type of psoriasis (generalized pustular psoriasis, GPP).
What do I need to tell the doctor BEFORE my child takes this drug?
- If your child is allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell the doctor about the allergy and what signs your child had.
- If your child has an infection.
- If your child has TB (tuberculosis).
This is not a list of all drugs or health problems that interact with this drug.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe to give this drug with all of your child’s other drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.
What are some things I need to know or do while my child takes this drug?
- Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
- Your child will need a TB (tuberculosis) test before starting this drug.
- Your child may have more chance of getting infections. Have your child wash hands often. Avoid crowds and people with infections, colds, or flu.
- If possible, make sure all vaccines are up to date before treatment with this drug.
- Talk with the doctor before having your child get any vaccines during treatment and for at least 16 weeks after you child’s last dose of this drug. Use of some vaccines with this drug may either raise the chance of an infection or make the vaccine not work as well.
If your child is pregnant or breast-feeding a baby:
- Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks to your child and the baby.
What are some side effects that I need to call my child’s doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
- Vaginal itching or discharge.
- A severe and sometimes deadly reaction has happened. Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. If you have questions, talk with the doctor.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if your child has any side effects that bother your child or do not go away.
- Feeling tired or weak.
- Upset stomach or throwing up.
- Diarrhea.
- Headache.
- Joint pain.
- Bruising where the shot is given.
- Swelling, warmth, or redness where this drug was given.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.
How is this drug best given?
Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.
Injection (subcutaneous):
- It is given as a shot into the fatty part of the skin on the top of the thigh or the belly area.
- If you will be giving your child the shot, your child’s doctor or nurse will teach you how to give the shot.
- Wash your hands before and after use.
- Do not use if the solution is cloudy, leaking, or has particles.
- This drug is clear to brownish-yellow. Do not use if the solution changes color. If you are not sure, talk with the pharmacist.
- Do not give into skin within 2 inches (5 cm) of the belly button.
- Do not give into skin that is irritated, tender, bruised, red, scaly, hard, scarred, or has stretch marks.
- Inject at least 1 inch away from where the last dose was given. If your child’s dose has more than 1 injection, give the injections into 2 different places at least 1 inch apart.
- Before using this drug, take it out of the refrigerator. Allow to reach room temperature (15 to 30 minutes). Do not heat this drug.
- Throw away after using. Do not use the device more than 1 time.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
- If you drop the device, be sure you know if it can be used or if you need to replace it. If you are not sure, read the package insert. If you have questions, talk with the doctor or pharmacist.
Injection (I.V.):
- It is given as an infusion into a vein over a period of time.
What do I do if my child misses a dose?
Injection (subcutaneous):
- Give a missed dose as soon as you think about it.
- If it is almost time for the next dose, skip the missed dose and return to your child’s regular schedule.
- Do not give 2 doses at the same time or extra doses.
- If you are not sure what to do if your child misses a dose, call the doctor.
Injection (I.V.):
- Call your doctor to find out what to do.
How do I store and/or throw out this drug?
Injection (subcutaneous):
- Store in a refrigerator. Do not freeze.
- Do not use if it has been frozen.
- If needed, this drug can be left out at room temperature for up to 24 hours. Throw away drug if left at room temperature for more than 24 hours.
Injection (I.V.):
- If you need to store this drug at home, talk with your doctor, nurse, or pharmacist about how to store it.
All products:
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
General drug facts
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Consumer Information Use and Disclaimer
This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.
Last Reviewed Date
2024-04-10
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