Artificial Intelligence Calculator for Recurrence Following Surgery

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Using new machine-learning classifiers called optimal classification trees, our artificial intelligence (AI)-based calculator is designed to predict the probability of gastrointestinal stromal tumor recurrence five years following the complete resection (surgical removal of all cancerous tissue) of the gastrointestinal stromal tumor. It is designed for patients who have not received tyrosine kinase inhibitors before or after surgery.

Results produced by this tool are based on data from patients treated at MSK, a large research institution with surgeons who perform a high volume of gastrointestinal stromal tumor procedures, and at 80 sites comprising the Spanish Group for Research in Sarcomas. The AI tool predictions were validated using external data from 7 sites comprising the Polish Clinical GIST Registry. All results must be understood in the context of each patient’s specific treatment plan. Patients and caregivers using this tool should discuss the result with the patient’s physician.

To gather the information required to use this AI-based calculator, use our worksheet.

Enter Your Information

All fields are required unless noted optional
per 50 HPF (equivalent to mitotic count per 5 mm2) (0 to 220)
What is mitotic count?
Mitotic count refers to the number of cells undergoing mitosis (cell division) when viewed under the microscope.
cm (0 to 33)
Note: For tumors less than 7.15 cm, the algorithm does not account for the tumor site. Therefore, for these tumors, we should clarify that the probability of recurrence reflects a mixture of gastric and non-gastric site tumors. This contrasts with tumors equal to or larger than 7.15 cm, where the probability of recurrence is influenced by the tumor site.

Thus, for accurate recurrence risk calculations, tumor size and mitotic count inputs are needed for patients with tumors smaller than 7.15 cm. For patients with tumors equal or larger than 7.15 cm, inputs for tumor size, mitotic count, and tumor site are required