MSK Kids offers a range of clinical trials evaluating new approaches for children with Ewing sarcoma. Trials are available for newly diagnosed children and for those whose cancer has continued growing or come back after treatment.  

Some of our clinical trials are evaluating new drugs. Others are assessing existing drugs and drug combinations used in adults with cancer that may be useful in young people with Ewing sarcoma. For example, our investigators learned through a clinical trial that irinotecan (Camptosar^®) and temozolomide (Temodar^®) — drugs already used to treat colorectal cancer and brain cancer in adults — are effective against Ewing sarcoma that come backs after standard treatment. Today, these two medications are now part of the arsenal of standard therapies we use to treat newly diagnosed Ewing sarcoma.

Your child’s care team will let you know if your child can participate in a clinical trial. The decision to enroll is entirely voluntary. The study team will explain the benefits and risks of the study to you so you can make an informed decision.