Molecular Microbiology: Publications

Molecular Microbiology: Publications

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Below is a selection of high-impact publications in which MMF collaborated with sample processing, sequencing, and expertise:

  • Abate M, Vos E, Gonen M, Janjigian Y, Schattner M, Laszkowska M, Tang L, Maron S, Coit D, Vardhana S, Vanderbilt C, Strong V. A Novel Microbiome Signature in Gastric Cancer. Ann Surg 2022 Oct; 276(4):605-615. doi: 10.1097/SLA.0000000000005587
  • Smith M, Dai A, Ghilardi G, Amelsberg KV, Devlin SM, Pajarillo R, Slingerland JB, Beghi S, Herrera PS, Giardina P, Clurman A, Dwomoh E, Armijo G, Gomes ALC, Littmann ER, Schluter J, Fontana E, Taur Y, Park JH, Palomba ML, Halton E, Ruiz J, Jain T, Pennisi M, Afuye AO, Perales MA, Freyer CW, Garfall A, Gier S, Nasta S, Landsburg D, Gerson J, Svoboda J, Cross J, Chong EA, Giralt SA, Gill SI, Riviere I, Porter DL, Schuster SJ, Sadelain M, Frey N, Brentjens RJ, June CH, Pamer EG, Peled JU, Facciabene A, van den Brink MRM, Ruella M. Gut Microbiome Correlates of Response and Toxicity Following Anti-CD19 CAR T Cell Therapy. Nat Med 2022 Oct; 28:713-723. doi: 10.1038/s41591-022-01702-9
  • Zegarra-Ruiz DF, Kim DV, Norwood K, Kim M, Wu WJH, Saldana-Morales FB, Hill AA, Majumdar S, Orozco S, Bell R, Round JL, Longman RS, Egawa T, Bettini ML, Diehl GE. Thymic Development of Gut-Microbiota-specific T Cells. Nature 2021 May; 594:413-417. doi: 10.1038/s41586-021-03531-1
  • Wipperman MF, Bhattarai SK, Vorkas CK, Maringati VS, Taur Y, Mathurin L, McAulay K, Vilbrun SC, Francois D, Bean J, Walsh KF, Nathan C, Fitzgerald DW, Glickman MS, Bucci V. Gastrointestinal Microbiota Composition Predicts Peripheral Inflammatory State during Treatment of Human Tuberculosis. Nat Comm 2021 Feb; 12:1141. doi: 10.1038/s41467-021-21475-y
  • Schluter J, Peled JU, Taylor BP, Markey KA, Smith M, Taur Y, Niehus R, Staffas A, Dai A, Fontana E, Amoretti LA, Wright RJ, Morjaria S, Fenelus M, Pessin MS, Chao NJ, Lew M, Bohannon L, Bush A, Sung AD, Hohl TM, Perales MA, van den Brink MRM, Xavier JB. The Gut Microbiota is Associated with Immune Cell Dynamics in Humans. Nature 2020 Nov; 588:303-307. doi: 10.1038/s41586-020-2971-8
  • Peled JU, Gomes ALC, Devlin SM, Littmann ER, Taur Y, Dung AD, Weber D, Hashimoto D, Slingerland AE, Slingerland JB, Maloy M, Clurman AG, Stein-Thoeringer CK, Markey KA, Docampo M, da Silva MB, Khan N, Gessner A, Messina JA, Romero K, Lew MV, Bush A, Bohannon L, Brereton DG, Fontana E, Amoretti LA, Wright RJ, Armijo GK, Shono Y, Sanchez-Escamilla M, Flores NC, Tomas AA, Lin RJ, Segundo LYS, Shah GL, Cho C, Scordo M, Politikos I, Hayasaka K, Hasegawa Y, Gyurkocza B, Ponce DM, Barker JN, Perales MA, Giralt SA, Jenq RR, Teshima T, Chao NJ, Holler E, Xavier JB, Pamer EG, van den Brink MRM. Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation. N Engl J Med 2020 Feb; 382:822-834. doi: 10.1056/NEJMoa1900623
  • Zhai B, Ola M, Rolling T, Tosini NL, Joshowitz S, Littmann ER, Amoretti LA, Fontana E, Wright RJ, Miranda E, Veelken CA, Morjaria SM, Peled JU, van den Brink MRM, Babady E, Butler G, Taur Y, Hohl TM. High-resolution Mycobiota Analysis Reveals Dynamic Intestinal Translocation Preceding Invasive Candidiasis. Nat Med 2020 Jan; 26:59-64. doi: 10.1038/s41591-019-0709-7
  • Markey KA, Schluter J, Gomes ALC, Littmann ER, Pickard AJ, Taylor BP, Giardina PA, Weber D, Dai A, Docampo MD, Armijo GK, Slingerland AE, Slingerland JB, Nichols KB, Brereton DG, Clurman AG, Ramos RJ, Rao A, Bush A, Bohannon L, Covington M, Lew MV, Rizzieri DA, Chao N, Maloy M, Cho C, Politikos I, Giralt SA, Taur Y, Pamer EG, Holler E, Perales MA, Ponce DM, Devlin SM, Xavier J, Sung AD, Peled JU, Cross JR, van den Brink MRM. The Microbe-derived Short-chain Fatty Acids Butyrate and Propionate are Associated with Protection from Chronic GVHD. Blood 2020 July; 136(1):130-136. doi: 10.1182/blood.2019003369
  • Stein-Thoeringer CK, Nichols KB, Lazrak A, Docampo MD, Slingerland AE, Slingerland JB, Clurman AG, Armijo G, Gomes ALC, Shono Y, Staffas A, Burgos da Silva M, Devlin SM, Markey KA, Bajic D, Pinedo R, Tsakmaklis A, Littmann ER, Pastore A, Taur Y, Monette S, Arcila ME, Pickard AJ, Maloy M, Wright RJ, Amoretti LA, Fontana E, Pham D, Jamal MA, Weber D, Sung AD, Hashimoto D, Sheid C, Xavier JB, Messina JA, Romero K, Lew M, Bush A, Bohannon L, Hayasaka K, Hasegawa Y, Vehreschild MJGT, Cross JR, Ponce DM, Perales MA, Giralt SA, Jenq RR, Teshima T, Holler E, Chao NJ, Pamer EG, Peled JU, van den Brink MRM. Lactose Drives Enterococcus Expansion to Promote Graft-versus-Host Disease. Science 2019 Nov; 366(6469):1143-1149. doi: 10.1126/science.aax3760
  • Taur Y, Coyte K, Schluter J, Robilotti E, Figueroa C, Gjonbalaj M, Littmann ER, Ling L, Miller L, Gyaltshen Y, Fontana E, Morjaria S, Gyurkocka B, Perales MA, Castro-Malaspina H, Tamari R, Ponce DM, Koehne G, Barker J, Jakubowski A, Papadopoulos E, Dahi P, Sauter C, Shaffer B, Young JW, Peled JU, Meagher RC, Jenq RR, van den Brink MRM, Giralt SA, Pamer EG, Xavier JB. Reconstitution of the Gut Microbiota of Antibiotic-treated Patients by Autologous Fecal Microbiota Transplant. Sci Trans Med 2018 Sep; 10(460). doi: 10.1126/scitranslmed.aap9489
  • Dubin K, Callahan MK, Ren B, Khanin R, Viale A, Ling L, No D, Gobourne A, Littmann E, Huttenhower C, Pamer EG, Wolchok JD. Intestinal Microbiome Analyses Identify Melanoma Patients at Risk for Checkpoint-blockade-induced Colitis. Nat Comm 2016 Feb; 7:10391. doi: 10.1038/ncomms10391
  • Shono Y, Docampo MD, Peled JU, Perobelli SM, Velardi E, Tsai JJ, Slingerland AE, Smith OM, Young LF, Gupta J, Lieberman SR, Jay HV, Ahr KF, Porosnicu Rodriguez KA, Xu K, Calarfiore M, Poeck H, Caballero S, Devlin SM, Rapaport F, Dudakov JA, Hanash AM, Gyurkocza B, Murphy GF, Gomes C, Liu C, Moss EL. Falconer SB, Bhatt AS, Taur Y, Pamer EG, van den Brink MRM, Jenq RR. Increased GVHD-related Mortality with Broad-spectrum Antibiotic Use after Aloggeneic Hematopoietic Stem Cell Transplantation in Human Patients and Mice. Sci Trans Med 2016 May; 8(339):339ra71. Doi: 10.1126/scitranslmed.aaf2311