Recent MSK Discoveries & Advances

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Recent MSK Discoveries & Advances

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Memorial Sloan Kettering researchers are relentlessly exploring every aspect of cancer — from basic investigations of cells and molecules to clinical trials of new treatments and population-wide studies of the disease. While our core mission is to translate this knowledge into new strategies to control cancer, many of our investigators are also making scientific progress against other diseases and conditions.

Below are some examples of discoveries and advances that recently were made in our laboratories and clinics, and featured in our news stories.

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375 News Items found
In the Lab
Three-dimensional reconstruction of the blood vessels in a mouse thymus using light-sheet fluorescent microscopy
New Hope for Repairing a Damaged or Aging Immune System

Scientists have uncovered a molecule that, in mice, can promote the regeneration of the thymus, where T cells develop.
Q&A
MP1104 binding to the kappa opioid receptor
Building a Safer Opioid: MSK Research Seeks to Develop New Ways to Relieve Pain

Science could lead to a new type of opioid drug that blocks pain but has a lower potential for addiction or abuse.
In the Lab
cryo-EM picture of mTORC1
Scientists Unlock Structure of mTOR, a Key Cancer Cell Signaling Protein

Structural biologists in the Sloan Kettering Institute have used a powerful tool called cryo-EM to solve the structure of a major cancer player.
In the News
Gears with 2016 and 2017
Year in Review: The Science and Technology that Shaped Cancer Care in 2017

As 2017 draws to a close, take a look back at the scientific discoveries that deepened our understanding of cancer in the past year.
In the Lab
Sloan Kettering Institute Director Joan Massagué with laboratory member Karuna Ganesh
When Cancer Spreads: Research Focuses on Better Ways to Treat Metastasis

MSK investigators are learning how cancer cells escape from the original tumor and hide out in the body. Their goal is to prevent metastatic tumors from forming.
In the Lab
A microscopic view of genetically engineered mouse tumor and a human FL-HCC tumor
With Help of CRISPR, Scientists Unravel the Cause of a Rare Liver Cancer

A team led by MSK molecular biologist Scott Lowe is making progress against fibrolamellar hepatocellular carcinoma.
Announcement
Gloved hand and magnifying glass on banded DNA sequences
FDA Authorizes MSK-IMPACT Test for Analyzing Patient Tumors

The test, developed at MSK, looks for alterations in 468 genes that are seen in both common and rare cancers.
Science Byte
Prostate cancer cells, colored red in scanning electron micrograph (SEM).
PSMA: A New Target for Prostate Cancer Treatment

Researchers have discovered how a high level of the protein PSMA in cells helps fuel prostate cancer.
Feature
Former MSK president Paul Marks
The Man behind the Prize: How Paul Marks Shaped Modern Cancer Research

Recent advances in epigenetic and targeted therapies owe a lot to the foresight of former MSK President Paul Marks, who believed in the importance of basic research.
In the Lab
iron-filled macrophages from a breast cancer tumor
MSK-Developed Technology Provides a “Virtual Biopsy” of Immune Cells in Tumors

The noninvasive approach could help scientists track the movements of an important cell type that can influence the outcome of cancer treatment.