Setting the Gold Standard in Patient Reported Outcome Measures

Our Value Proposition

The Q-Portfolio is a collection of Patient Reported Outcome Measures (PROMs), which have been rigorously developed and clinically validated by a distinguished team of global investigators. PROMs (also known as Patient Reported Outcome or PRO questionnaires) provide valuable insights by capturing data directly from patients.  This might include a patient’s description of symptoms, satisfaction with care—including specific therapies or products—and personal assessments of how a treatment or condition affects their physical, mental, emotional, and social well-being. 

Within this important field, the Q-Portfolio is renowned. Its noteworthy advantages include:

• Q-Portfolio PROMs offer a broad range of potential uses in product development, patient care, outcome reporting, benchmarking, and clinical research.
• Specific scales within three of the Q-Portfolio questionnaires received FDA approval as Medical Device Development Tools (MDDTs) for Clinical Outcome Assessments (COAs).
• Q-Portfolio PRO scales have been extensively utilized in clinical research, including as clinical trial endpoints and regulatory submission datapoints.
• Numerous commercial entities have utilized Q-Portfolio PROMs for product development and clinical research, including pharmaceutical companies, device manufacturers, and cosmetic manufacturers.
• Q-Portfolio PROMs are also applicable for use in digital health product development.

All Q-Portfolio questionnaires are copyright protected and some have been trademarked.

Commercial Licensing Opportunities

The Q-Portfolio is available for non-exclusive licensing to commercial entities such as pharmaceutical companies (for use in product development or clinical trials), investigator-initiated trials funded by for-profit entities, and providers of electronic platforms for PROMs administration. 

MSK manages the licensing of BREAST-Q®, FACE-Q®, BODY-Q®, WOUND-Q^TM, LYMPH-Q^TM, and HAND-Q^TM.

Non-Profit/Academic Use

Q-Portfolio questionnaires are available at no charge to non-profit entities for use in research and clinical practice.  For information, please contact: [email protected].

MSK licensing opportunities include:

The BREAST-Q®

The BREAST-Q® questionnaire is a rigorously developed PROM for use in cosmetic and reconstructive breast surgery and clinical practice.  With a focus on quality of life and patient satisfaction, the BREAST-Q® consists of independent modules relating to augmentation, reduction/mastopexy, and breast cancer (mastectomy, breast-conserving therapy, and reconstruction). 

First published in 2009, the BREAST-Q® has been licensed for use by 7,000+ clinicians and researchers in more than 75 countries.  In 2020, the U.S. FDA qualified the BREAST-Q® Reconstruction Module as a Medical Device Development Tool, specifically qualifying these scales:  Physical Well-being (chest), Psychosocial Well-being, Sexual Well-being, and Satisfaction with Breasts.

See here for detailed product sheet, including information about BREAST-Q® licensing options.  For questions and licensing, contact the licensing team at [email protected]. 

The FACE-Q®

The FACE-Q® questionnaire is a rigorously developed PROM including 40, independently functioning scales/checklists in the Aesthetics module alone that measure outcomes important to patients from their perspective.  It can be used to measure treatment outcomes and other patient assessments relating to aesthetics, craniofacial conditions, head and neck cancers, paralysis, and skin cancers.  With broad applicability, the FACE-Q® questionnaire has been extensively utilized in clinical research and both cosmetic and therapeutic product development.

In 2022, 11 of the FACE-Q® scales were qualified by the U.S. FDA as Medical Device Development Tools. These scales measure appearance (face, cheeks, lips, skin, nasolabial tools, and glabella lines) and health-related quality of life (aging appraisal, early life impact of treatment, satisfaction with outcome, psychological function, and social function). 

See here for detailed product sheet, including information about FACE-Q® licensing options.  For questions and licensing, contact the licensing team at [email protected]. 

The BODY-Q®

The BODY-Q® questionnaire was developed from interviews with people undergoing weight loss treatments and body contouring to remove excess skin after massive weight loss and for cosmetic reasons.  It includes an obesity-specific symptom checklist and 31 independently functioning scales that measure appearance, health-related quality of life, eating-related concerns, and experience of care.

See here for detailed product sheet, including information about BODY-Q® licensing options.  For questions and licensing, contact the licensing team at [email protected].

The WOUND-Q^TM

The WOUND-Q^TM questionnaire was developed and validated from an international sample of patients with chronic wounds.  It includes multiple independent scales measuring wound characteristics, health-related quality of life, experience of care, and wound treatment. 

The WOUND-Q^TM questionnaire was MDDT-qualified by the U.S. FDA in 2024 for use by adult participants (22 years of age and older).  It is qualified for use in clinical studies or trials, in which they may complete paper or electronic versions of seven scales to self-report on different aspects of their wound characteristics and/or health related quality of life affected by a nonhealing wound in any anatomic location.

See here for detailed product sheet, including information about WOUND-Q licensing options. For questions and licensing, contact the licensing team at [email protected].

The LYMPH-Q^TM

The LYMPH-Q^TM Upper Extremity was developed and validated from an international sample of women treated for breast cancer who developed arm lymphedema.  It includes 7 independent scales measuring function, symptoms, life impact, psychological, arm sleeve, and information. 

In a field of patient care and research that has had little consensus for measuring outcomes, the LYMPH-Q represents a key step forward, as clinicians and researchers seek to evaluate outcomes important to women suffering from arm lymphedema following breast cancer.

For questions and licensing, contact the licensing team at [email protected].

The HAND-Q^TM

The HAND-Q^TM was developed and validated from an international sample of people with any type of congenital or acquired condition affecting the hands. It includes 14 independent scales measuring four overarching domains: appearance, health-related quality of life, experience of care, and treatment.

For questions and licensing, contact the licensing team at [email protected].

More on the Q-Portfolio

The Q-Portfolio’s leadership team includes its three co-developers:

• Andrea Pusic, MD, MHS, FACS, FRCSC, Chief of Plastic & Reconstructive Surgery, Brigham and Women’s Hospital; Joseph E. Murray Professor of Surgery at Harvard Medical School.  Dr. Pusic previously served as a Surgeon at MSK, where she established the electronic platform for collection and use of BREAST-Q data in clinical care.
• Anne Klassen, DPhil, Professor, Department of Pediatrics, and Associate Member of the Departments of Surgery & Health Research Methods, Evidence & Impact, McMaster University (Canada). Dr. Klassen is also an Adjunct Professor in the Faculty of Health Sciences, University of Southern Denmark.
• Stefan Cano, PhD, CPsychol, AFBPSS, Chief Scientific Officer, Modus Outcomes, a division of Thread Research.  Dr. Cano is a Chartered Psychologist and Associate Fellow of the British Psychological Society.

The Q-Portfolio includes nearly 20 Patient Reported Outcome questionnaires, including ACNE-Q, CLEFT-Q, EAR-Q, GENDER-Q, HAIR-Q, LIMB-Q, NAIL-Q, SCAR-Q, and SKIN-Q. For a complete list and detailed product information, visit the Q-Portfolio’s website.