Adam Schmitt: Publications

The Adam Schmitt Lab
Publications

Adam Schmitt: Publications

Share
Share

Yu AF, Moore ZR, Moskowitz CS, Liu JE, Dang CT, Ramanathan L, Oeffinger KC, Steingart RM, Schmitt AM. Association of Circulating Cardiomyocyte Cell-Free DNA With Cancer Therapy-Related Cardiac Dysfunction in Patients Undergoing Treatment for ERBB2-Positive Breast Cancer. JAMA Cardiol. 2023 Jul 1;8(7):697-702. doi: 10.1001/jamacardio.2023.1229. PubMed PMID: 37256614; PubMed Central PMCID: PMC10233452.

Shamseddine A, Patel SH, Chavez V, Moore ZR, Adnan M, Di Bona M, Li J, Dang CT, Ramanathan LV, Oeffinger KC, Liu JE, Steingart RM, Piersigilli A, Socci ND, Chan AT, Yu AF, Bakhoum SF, Schmitt AM. Innate immune signaling drives late cardiac toxicity following DNA-damaging cancer therapies. J Exp Med. 2023 Mar 6;220(3). doi: 10.1084/jem.20220809. Epub 2022 Dec 19. PubMed PMID: 36534085; PubMed Central PMCID: PMC9767651.

Peng KL, Vasudevan HN, Lockney DT, Baum R, Hendrickson RC, Raleigh DR, Schmitt AM. Miat and interacting protein Metadherin maintain a stem-like niche to promote medulloblastoma tumorigenesis and treatment resistance. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2203738119. doi: 10.1073/pnas.2203738119. Epub 2022 Sep 6. PubMed PMID: 36067288; PubMed Central PMCID: PMC9478675.

Marney CB, Anderson ES, Baum R, Schmitt AM. A Unique Spectrum of Spontaneous Tumors in Dino Knockout Mice Identifies Tissue-Specific Requirements for Tumor Suppression. Cells. 2022 Jun 2;11(11). doi: 10.3390/cells11111818. PubMed PMID: 35681513; PubMed Central PMCID: PMC9180304.

Marney CB, Anderson ES, Adnan M, Peng KL, Hu Y, Weinhold N, Schmitt AM. p53-intact cancers escape tumor suppression through loss of long noncoding RNA Dino. Cell Rep. 2021 Jun 29;35(13):109329. doi: 10.1016/j.celrep.2021.109329. PubMed PMID: 34192538; PubMed Central PMCID: PMC8287872.

Schmitt AM, Chang HY. Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology. Cold Spring Harb Perspect Med. 2017 Jul 5;7(7). doi: 10.1101/cshperspect.a026492. Review. PubMed PMID: 28193769; PubMed Central PMCID: PMC5495049.

Schmitt AM, Garcia JT, Hung T, Flynn RA, Shen Y, Qu K, Payumo AY, Peres-da-Silva A, Broz DK, Baum R, Guo S, Chen JK, Attardi LD, Chang HY. An inducible long noncoding RNA amplifies DNA damage signaling. Nat Genet. 2016 Nov;48(11):1370-1376. doi: 10.1038/ng.3673. Epub 2016 Sep 26. PubMed PMID: 27668660; PubMed Central PMCID: PMC5083181.

Schmitt AM, Chang HY. Long Noncoding RNAs in Cancer Pathways. Cancer Cell. 2016 Apr 11;29(4):452-463. doi: 10.1016/j.ccell.2016.03.010. Review. PubMed PMID: 27070700; PubMed Central PMCID: PMC4831138.

Voce DJ, Schmitt AM, Uppal A, McNerney ME, Bernal GM, Cahill KE, Wahlstrom JS, Nassiri A, Yu X, Crawley CD, White KP, Onel K, Weichselbaum RR, Yamini B. Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor. Oncogene. 2015 May 21;34(21):2807-13. doi: 10.1038/onc.2014.211. Epub 2014 Jul 21. PubMed PMID: 25043302; PubMed Central PMCID: PMC4302074.

Schmitt AM, Yamini B. Nfkb1 suppresses DNA alkylation-induced tumor formation. Mol Cell Oncol. 2015 Jan-Mar;2(1):e968073. doi: 10.4161/23723548.2014.968073. eCollection 2015 Jan-Mar. PubMed PMID: 27308399; PubMed Central PMCID: PMC4905238.

Schmitt AM, Chang HY. Gene regulation: Long RNAs wire up cancer growth. Nature. 2013 Aug 29;500(7464):536-7. doi: 10.1038/nature12548. Epub 2013 Aug 14. PubMed PMID: 23945584; PubMed Central PMCID: PMC5332550.

Crawley CD, Raleigh DR, Kang S, Voce DJ, Schmitt AM, Weichselbaum RR, Yamini B. DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-κB p50 and a single nucleotide in the κB-site. Nucleic Acids Res. 2013 Jan;41(2):764-74. doi: 10.1093/nar/gks1120. Epub 2012 Nov 24. PubMed PMID: 23180782; PubMed Central PMCID: PMC3553961.

Schmitt AM, Crawley CD, Kang S, Raleigh DR, Yu X, Wahlstrom JS, Voce DJ, Darga TE, Weichselbaum RR, Yamini B. p50 (NF-κB1) is an effector protein in the cytotoxic response to DNA methylation damage. Mol Cell. 2011 Dec 9;44(5):785-96. doi: 10.1016/j.molcel.2011.09.026. PubMed PMID: 22152481; PubMed Central PMCID: PMC3240852.

Schmitt AM, Shi J, Wolf AM, Lu CC, King LA, Zou Y. Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping. Nature. 2006 Jan 5;439(7072):31-7. doi: 10.1038/nature04334. PubMed PMID: 16280981.