A quiescent human glioblastoma stem cell gene expression signature. 2020. Xuanhua P. Xie, Dan R. Laks, Daochun Sun, Zilai Wang, Tejus Bale, Viviane Tabar, Cameron Brennan, Xiuping Zhou, Luis F. Parada; Submitted.

Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression. 2020. Daochun Sun, X. Peter Xie, Xiyuan Zhang, Zilai Wang, Sameer Farouk Sait, Swathi V. Iyer, Yu-Jung Chen, Rebecca Brown, Dan R. Laks, Mollie E. Chipman, Jack F. Shern, and Luis F. Parada. 2021, Cell Stem Cell, Accepted for publication.

Cell Lineage-Based Stratification for Glioblastoma. Wang Z, Sun D, Chen YJ, Xie X, Shi Y, Tabar V, Brennan CW, Bale TA, Jayewickreme CD, Laks DR, Alcantara Llaguno S, Parada LF. Cancer Cell. 2020 Sep 14;38(3):366-379.e8. doi: 10.1016/j.ccell.2020.06.003. Epub 2020 Jul 9. PMCID: PMC7494533.

High resolution subventricular zone stem cell niche transcriptome reveals features of lineage, anatomy, and aging.  Xie XP, Laks DR,  Sun D, Poran A,  Laughney AM,  Wang Z, Sam J, Belenguer G, Fariñas I, Elemento O, Zhou X, Parada LF., 2020. Proceedings of the National Academy of Sciences. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31448-31458. doi: 10.1073/pnas.2014389117. Epub 2020 Nov 23.

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Shi Y, Lim SK, Liang Q, Iyer SV, Wang HY, Wang Z, Xie X, Sun D, Chen YJ, Tabar V, Gutin P, Williams N, De Brabander JK, Parada LF. Nature. 2019 Mar;567(7748):341-346. doi: 10.1038/s41586-019-0993-x. Epub 2019 Mar 6.

Cell of Origin Susceptibility to Glioblastoma Formation Declines with Neural Lineage Restriction. Alcantara Llaguno S, Sun D, Pedraza AM, Vera E, Wang Z, Burns DK, Parada LF. Nat Neurosci. 2019 Apr;22(4):545-555. doi: 10.1038/s41593-018-0333-8. Epub 2019 Feb 18.

TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response. Ma Z, Zang T, Birnbaum SG, Wang Z, Johnson JE, Zhang CL, Parada LF. Nat Commun. 2017 Nov 21;8(1):1668. doi: 10.1038/s41467-017-01709-8.

Brain Tumor Stem Cells Remain in Play. Parada LF, Dirks PB, Wechsler-Reya RJ. J Clin Oncol. 2017 Jul 20;35(21):2428-2431. doi: 10.1200/JCO.2017.73.9540. Epub 2017 Jun 22. No abstract available.

Sheila R. Alcantara Llaguno1, Zilai Wang1, Daochun Sun1, Jian Chen1, Jing Xu1, Euiseok Kim, Kimmo J. Hatanpaa, Jack M. Raisanen, Dennis K. Burns, Jane E. Johnson, Luis F. Parada1. Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes. Cancer Cell 2015; Volume 28, Issue 4; October 12, 2015; p.429-440.