The investigators of Memorial Sloan Kettering Cancer Center have been invited to submit competitive research applications for support from the CER. The goal is to support highly creative and innovative research in epigenetics at MSKCC, and especially projects that have the potential to lead to significant scientific breakthroughs in epigenetics research.
2023 Requests for Proposals
Research Grants have been funded (2 years support): These awards serve to provide support for projects that are focused on technology development and/or bringing new high-impact technologies into MSK.
Awarded Projects:
Dr. Omar Abdel-Wahab
Understanding R-loops through high-resolution mapping at single cell level.
Dr. Thomas Vierbuchen
Implementing next generation methods for mapping chromatin states to identify locus-specific effects of transposable elements on gene regulation.
2020 Requests for Proposals
Two types of research projects have been funded:
Pilot Project Grants (1 year support): These awards serve to provide seed money for pilot and feasibility studies, in which epigenetics is a main component, with the resulting data serving as a basis for grant applications to outside agencies.
Project Collaborative Grants (2 years support). These awards require the collaboration between at least two MSK laboratories. Successful proposals use multidisciplinary approaches to obtain mechanistic insights into the role of epigenetic regulation in cellular processes, cell proliferation, differentiation, development and cancer.
Awarded Pilot Projects:
Dr. Maria Jasin
Impact of histone modifications on homologous recombination.
Dr. Alexandros Pertsinidis
Transcription control by Super-Elongation Complexes (SEC) in development and cancer.
Awarded Collaborative Projects:
Dr. Thomas Vierbuchen / Co-Investigator: Dr Danwei Huangfu
Characterizing the role of canonical and non-canonical SWI/SNF complexes in lineage specification from pluripotent stem cells.
Dr. Yael David / Co-Investigator: Dr. Xiolan Zhao
Studies of Smc5/6 as a multi-functional chromatin regulator.
Dr. Donna Pe’er / Co-Investigator: Dr. Anna-Katerina Hadjantonakis
Epigenetic mechanisms of visceral organ development.