Single-cell sequencing of breast tumors captures immune cells of different origins

Single-cell sequencing reveals that organs are prepatterned in the early mouse endoderm

Droplet microfluidic technology allows thousands of individual cells at a time to be sequenced separately

The Single-Cell Analytics Innovation Lab (SAIL) is a leading platform for cutting-edge molecular profiling and data analysis, serving the broader Memorial Sloan Kettering community. SAIL is led by Dana Pe’er, Chair of the Computational and Systems Biology Program in the Sloan Kettering Institute, and Ronan Chaligné. Dr. Pe’er pioneered a number of foundational analytical concepts and algorithms in the single-cell field. Dr. Chaligné is an expert in single-cell technologies and their application to biological questions, and has developed methods to profile multiple data types from the same cell.

Since its inception within the Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (GMTEC) in 2017, SAIL has grown to serve more than 50 laboratories spanning basic and translational research. Our mission is to assimilate emerging technologies in the rapidly advancing fields of single-cell sequencing and imaging-based profiling, in addition to providing robust analytical solutions. SAIL hosts a dedicated computational team that benchmarks new tools and generates pipelines to support an expanding set of technologies and data modalities.

You can learn more about the Single-Cell Analytics Innovation Lab here.