View a full listing of Immune Discovery & Modeling Service (IDMS): Publications’ journal articles.
Recent publications from our team.
Key Publications and Presentations by our team:
Papers:
Fraint E, Farooki S, Klein E, Mauguen A, Prockop SE, Scaradavou A, Curran K, Cancio M, Spitzer B, Boelens JJ, Oved J, Harris A, O’Reilly RJ, Kernan NA.Transplant Cell Ther. 2023 Jan;29(1):46.e1-46.e6. doi: 10.1016/j.jtct.2022.09.027. Epub 2022 Oct 6. PMID: 36210027
GPRC5D-Targeted CAR T Cells for Myeloma.
Mailankody S, Devlin SM, Landa J, Nath K, Diamonte C, Carstens EJ, Russo D, Auclair R, Fitzgerald L, Cadzin B, Wang X, Sikder D, Senechal B, Bermudez VP, Purdon TJ, Hosszu K, McAvoy DP, Farzana T, Mead E, Wilcox JA, Santomasso BD, Shah GL, Shah UA, Korde N, Lesokhin A, Tan CR, Hultcrantz M, Hassoun H, Roshal M, Sen F, Dogan A, Landgren O, Giralt SA, Park JH, Usmani SZ, Rivière I, Brentjens RJ, Smith EL.N Engl J Med. 2022 Sep 29;387(13):1196-1206. doi: 10.1056/NEJMoa2209900.PMID: 36170501 Clinical Trial.
Shah UA, Maclachlan KH, Derkach A, Salcedo M, Barnett K, Caple J, Blaslov J, Tran L, Ciardiello A, Burge M, Shekarkhand T, Adintori P, Cross J, Pianko MJ, Hosszu K, McAvoy D, Mailankody S, Korde N, Hultcrantz M, Hassoun H, Tan CR, Lu SX, Patel D, Diamond B, Shah G, Scordo M, Lahoud O, Chung DJ, Landau H, Usmani SZ, Giralt S, Taur Y, Landgren CO, Block G, Block T, Peled JU, van den Brink MRM, Lesokhin AM.Clin Cancer Res. 2022 Dec 1;28(23):5149-5155. doi: 10.1158/1078-0432.CCR-22-0723.PMID: 36170461
Andrlová H, Miltiadous O, Kousa AI, Dai A, DeWolf S, Violante S, Park HY, Janaki-Raman S, Gardner R, El Daker S, Slingerland J, Giardina P, Clurman A, Gomes ALC, Nguyen C, da Silva MB, Armijo GK, Lee N, Zappasodi R, Chaligne R, Masilionis I, Fontana E, Ponce D, Cho C, Bush A, Hill L, Chao N, Sung AD, Giralt S, Vidal EH, Hosszu KK, Devlin SM, Peled JU, Cross JR, Perales MA, Godfrey DI, van den Brink MRM, Markey KA. Sci Transl Med. 2022 May 25;14(646):eabj2829. doi: 10.1126/scitranslmed.abj2829. Epub 2022 May 25.PMID: 35613281
Meesters-Ensing JI, Admiraal R, Ebskamp L, Lacna A, Boelens JJ, Lindemans CA, Nierkens S.Front Pharmacol. 2022 Mar 18;13:828094. doi: 10.3389/fphar.2022.828094. eCollection 2022.PMID: 35370695
Admiraal R, Nierkens S, Bierings MB, Bredius RGM, van Vliet I, Jiang Y, Lopez-Yurda M, Versluijs AB, Zwaan CM, Lindemans CA, Boelens JJ.Lancet Haematol. 2022 Feb;9(2):e111-e120. doi: 10.1016/S2352-3026(21)00375-6.PMID: 35114150 Clinical Trial.
Miltiadous O, Waters NR, Andrlová H, Dai A, Nguyen CL, Burgos da Silva M, Lindner S, Slingerland J, Giardina P, Clurman A, Armijo GK, Gomes ALC, Lakkaraja M, Maslak P, Scordo M, Shouval R, Staffas A, O’Reilly R, Taur Y, Prockop S, Boelens JJ, Giralt S, Perales MA, Devlin SM, Peled JU, Markey KA, van den Brink MRM.Blood. 2022 May 5;139(18):2758-2769. doi: 10.1182/blood.2021014255.PMID: 35061893
Lakkaraja M, Scordo M, Mauguen A, Cho C, Devlin S, Ruiz JD, Klein E, Avecilla ST, Boulad F, Cancio MI, Curran KJ, Jakubowski AA, Kernan NA, Kung AL, O’Reilly RJ, Papadopoulos EB, Prockop S, van Roessel I, Scaradavou A, Shaffer BC, Shah G, Spitzer B, Tamari R, Giralt SA, Perales MA, Boelens JJ.Blood Adv. 2022 Feb 8;6(3):1054-1063. doi: 10.1182/bloodadvances.2021005584.PMID: 34788361
Szanto CL, Cornel AM, Tamminga SM, Delemarre EM, de Koning CCH, van den Beemt DAMH, Dunnebach E, Tas ML, Dierselhuis MP, Tytgat LGAM, van Noesel MM, Kraal KCJM, Boelens JJ, Huitema ADR, Nierkens S.Cancers (Basel). 2021 Apr 26;13(9):2096. doi: 10.3390/cancers13092096.PMID: 33926057
Harmonization, biomarkers, disease risk index.
Boelens JJ.Blood. 2021 Feb 18;137(7):874-875. doi: 10.1182/blood.2020009862.PMID: 33599765
de Koning C, Prockop S, van Roessel I, Kernan N, Klein E, Langenhorst J, Szanto C, Belderbos M, Bierings M, Boulad F, Bresters D, Cancio M, Curran K, Kollen W, O’Reilly R, Scaradavou A, Spitzer B, Versluijs B, Huitema A, Lindemans C, Nierkens S, Boelens JJ.Blood. 2021 Feb 11;137(6):848-855. doi: 10.1182/blood.2020007905.PMID: 33150379
Boelens JJ, Hosszu KK, Nierkens S.Front Pediatr. 2020 Aug 21;8:454. doi: 10.3389/fped.2020.00454. eCollection 2020.PMID: 32974239
van Roessel I, Prockop S, Klein E, Boulad F, Scaradavou A, Spitzer B, Kung A, Curran K, O’Reilly RJ, Kernan NA, Cancio M, Boelens JJ.Cytotherapy. 2020 Sep;22(9):503-510. doi: 10.1016/j.jcyt.2020.05.005. Epub 2020 Jul 1.PMID: 32622752
Oral Presentations:
Impact of Rabbit Anti-Thymocyte Globulin (rATG) Exposure in Ex Vivo T-Cell Depleted Hematopoietic Cell Transplantation in Children and Young Adults.
Lakkaraja M., Mauguen A., Boulad F., Cancio M.I., Curran K.J., Harris A., Kernan N.A., Klein E., Kung A.L., Oved J.H., Prockop S., Scaradavou A., Spitzer B., O’Reilly R.J., Boelens J.J. “Oral Presentation: 2023 Tandem Meetings Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, Orlando, Florida, February 2023.
Decreased neuroprotective analytes on day of infusion of chimeric antigen receptor (car) T cells are associated with neurotoxicity.
Lakkaraja M., Hosszu K., McAvoy D., Mauguen A., Purdon T.J., Khakoo Y., Santomasso B.D., Riviere I., Sadelain M., Curran K.J., Park J.H., Brentjens R.J., Boelens J.J. Oral Presentation: 47th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), March 2021.
Rabbit Anti-Thymocyte Globulin (ATG) Exposure after Ex Vivo T-Cell Depleted Hematopoietic Cell Transplantation Is Variable and Impacts Immune Reconstitution and Survival in Pediatric and Young Adult Patients.
Lakkaraja, M., Mauguen, A., Boulad, F., Spitzer, B., Scaradavou, A., Curran, K.J., Cancio, M.I., Roessel, I., Klein, E., Kernan, N.A., O’Reilly, R., Prockop, S. and Boelens, J.J. Oral Presentation: 46th Annual Meeting of the European Society for Blood and Marrow Transplantation, August 2020.
Posters:
Lakkaraja M., Hosszu K., McAvoy D., Mauguen A., Purdon T.J., Khakoo Y., Santomasso B.D., Senechal B.,Riviere I., Sadelain M., Curran K.J., Park J.H., Brentjens R.J., Boelens J.J.. Poster presentation: International Society for Cell & Gene Therapy (ISCT) 2022, San Francisco, May 2022.
Predictors for Neurotoxicity on Day of Infusion of Chimeric Antigen Receptor (CAR) T cells using Discovery Proteomics Platform.
Lakkaraja M., Hosszu K., McAvoy D., Mauguen A., Purdon T.J., Khakoo Y., Santomasso B.D., Senechal B.,Riviere I., Sadelain M., Curran K.J., Park J.H., Brentjens R.J., Boelens J.J.. Late Breaking abstract. Poster presentation: International Society for Cell & Gene Therapy (ISCT) 2021, May 2021
Lakkaraja, M., Scordo, M., Mauguen, A., Cho C., Devlin S., Avecilla S., Boulad F., Cancio, M., Curran, K., Jakubowski, A., Kernan N, Kung A., O’Reilly R., Papadopoulos E., Prockop S., Roessel I., Ruiz J., Scaradavou, A., Shaffer B., Shah G., Spitzer B., Tamari R., Giralt S., Perales MA, Boelens JJ. Poster presentation: 2020 American Society of Hematology (ASH) December 5, 2020.
Lakkaraja, M., Mauguen, A., Boulad, F., Spitzer, B., Scaradavou, A., Curran, K.J., Cancio, M.I., Roessel, I., Kernan, N.A., O’Reilly, R., Prockop, S. and Boelens, J.J. Poster presentation: 2020 Transplantation and Cellular Therapy Meetings of American Society of ASTCT and the CIBMTR. February 19, 2020, Orlando, Florida.