Mohr L, Toufektchan E, von Morgen P, Chu K, Kapoor A, Maciejowski J. ER-directed TREX1 limits cGAS activation at micronuclei. Mol Cell. 2021 Jan 12:S1097-2765(20)30958-8. doi: 10.1016/j.molcel.2020.12.037. Epub ahead of print. Maciejowski J, Chatzipli A, Dananberg A, Chu K, Toufektchan E, Klimczak LJ, Gordenin DA, Campbell PJ, de Lange T. APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis. Nat Genet. 2020 Sep;52(9):884-890. doi: 10.1038/s41588-020-0667-5. Epub 2020 Jul 27. PMCID: PMC7484228. Maciejowski J, Hatch EM. Nuclear Membrane Rupture and Its Consequences. Annu Rev Cell Dev Biol. 2020 Oct 6;36:85-114. doi: 10.1146/annurev-cellbio-020520-120627. Epub 2020 Jul 21. Petljak M, Maciejowski J. Molecular origins of APOBEC-associated mutations in cancer. DNA Repair (Amst). 2020 Oct;94:102905. doi: 10.1016/j.dnarep.2020.102905. Epub 2020 Jul 6. PMCID: PMC7494591 Maciejowski J, Drechsler H, Ballister E, Grundner-Culemann K, Foley EA, Lampson M, Daub H, McAinsh AD, Jallepalli PV. The Mps1-regulated phosphoproteome identifies Ska3 as an Mps1 substrate required for accurate chromosome segregation during mitosis. Developmental Cell. 2017 Apr 24; 41(2):143-156. PubMed Maciejowski J, de Lange T. Telomeres in Cancer: Tumor Suppression and Genome Instability. Nature Reviews Molecular Cell Biology. 2017 Mar; 18(3): 175-186. PubMed Maciejowski J, Imielinski M. Modeling cancer rearrangement landscapes. Current Opinion in Systems Biology. McIntyre RE, Nicod J, Robles-Espinoza CD, Maciejowski J, Cai N, Hill J, Verstraten R, Iyer V, Rust AG, Balmus G, Mott R, Flint J, Adams DJ. A Genome- Wide Association Study for Regulators of Micronucleus Formation in Mice. G3. 2016 May 27. PubMed Maciejowski J, Li Y, Bosco N, Campbell PJ, de Lange T. Chromothripsis and Kataegis Induced by Telomere Crisis. Cell. 2015 Dec 17;163(7):1641-54. PubMed Rodriguez-Bravo V, Maciejowski J, Corona J, Buch HK, Collin P, Kanemaki MT, Shah JV, Jallepalli PV. Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor. Cell. 2014 Feb 27; 156(5):1017-31. PubMed Paschal CR, Maciejowski J, Jallepalli PV. A stringent requirement for Plk1 T210 phosphorylation during K- ber assembly and chromosome congression. Chromosoma. 2012 Dec; 121(6):565-72. PubMed Maciejowski J, George KA, Terret ME, Zhang C, Shokat KM, Jallepalli PV. Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling. Journal of Cell Biology. 2010 Jul 12;190(1):89-100. PubMed McGovern M, Voutev R, Maciejowski J, Corsi AK, Hubbard EJ. A “latent niche” mechanism for tumor initiation. Proceedings of the National Academy of Sciences U S A. 2009 Jul 14;106(28): 11617-22. PubMed Burkard ME, Maciejowski J, Rodriguez-Bravo V, Repka M, Lowery DM, Clauser KR, Zhang C, Shokat KM, Carr SA, Yaffe MB, Jallepalli PV. Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells. PLoS Biology. 2009 May 5;7(5):e1000111. PubMed Maciejowski J, Ugel N, Mishra B, Isopi M, Hubbard EJ. Quantitative analysis of germline mitosis in adult C. elegans. Developmental Biology 2006 Apr 1;292(1): 142-51. PubMed Book traversal links for The John Maciejowski Lab Previous Featured News Next Open Positions