Daniel E. Prince, MD, MPH
Orthopaedic Surgeon
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Areas of Expertise
Conditions I Treat
- Pediatric sarcomas
- Pediatric bone tumors
- Congenital deformities
My Specialties
- Bone regeneration
- Limb reconstruction
About Me
- Associate Attending Surgeon
I am an orthopaedic surgeon on the MSK Kids team who specializes in the care of children, adolescents, and young adults with bone tumors and other diseases of the bone. I have expertise in a treatment called bone regeneration, which relies on the body’s natural abilities to regrow bone after a segment of bone is removed during cancer surgery. Bone regeneration is also the subject of my research.
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The bone regeneration approach is called “distraction osteogenesis” or “bone transport” and is an option for some patients with bone tumors. We remove the segment of a bone containing the tumor and stabilize the two remaining ends of the bone. A small piece of the remaining bone is slowly stretched, “tricking” the body into thinking there is a fracture, which triggers the healing process. Patients are fitted with a metal rod in the bone that can be elongated in a controlled way with a device that a parent, caregiver, or even the patient adjusts very slowly to lengthen the bone each day. The remaining bone then makes new bone which “jumps across” and bridges the gap over time. Ultimately, once the bone is fully healed, it becomes as strong as the original bone so all metal implants can be completely removed, and the patient can go back to full activity without any restrictions — unlike most standard reconstructions with metal or cadaver bone.
I find the phenomenon of bone regeneration to be fascinating, and it is one of the reasons I chose orthopedics as a field. It is amazing how the body can heal itself. The human body is so intricate and complex, with many parts working together. I am personally familiar with orthopedic oncology because I had a bone tumor myself in my upper arm when I was in college. I had the tumor removed and I wore external hardware on my arm for support while it healed.
I remember how anxious my mother was during that time, and it is something I keep in mind when I meet a new patient and his or her family. I’m a father of two sons myself, and I treat my patients as if they were my own children. I imagine what parents are going through, and my team and I try to give you answers as quickly as we can. We can’t eliminate your uncertainty, but we can give you a plan that lets you know what we can do for your child and provide you with reassurance about what to expect going forward.
The treatment process can be a lengthy one. Bone regeneration itself takes a few years, so I get to know my patients and their families closely as treatment progresses. I enjoy getting to know what they like, who are their friends in school, what games they like to play, and so forth. Whenever possible, I include even young patients in decision-making, and I help them to understand what they actually have control over, such as doing their physical therapy exercises or using the device that performs the bone lengthening. It gives them some input over a situation that they may often feel is beyond their control. I support my patients as much as needed so they can achieve the best outcomes possible.
An orthopaedic (OR-thuh-PEE-dik) surgeon is a doctor with special training in surgery on the musculoskeletal system. This includes the bones, joints, tendons, and muscles.
Conditions I Treat
- Pediatric sarcomas
- Pediatric bone tumors
- Congenital deformities
- Bone metastases (secondary bone cancer)
- Adamantinoma
- Fibrous dysplasia
- Ollier's disease
- Paget's disease of bone
My Specialties
- Bone regeneration
- Limb reconstruction
Education
- MD, Yale University Medical School
Residencies
- Orthopedics, New York Presbyterian/Columbia University
Fellowships
- Bone Regeneration, International Center for Limb Lengthening
- Orthopedic Oncology, Memorial Sloan Kettering Cancer Center
Board Certifications
- Orthopedic Surgery
Insurance Information
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In Network Coverage Type
PPO
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PPO, POS, EPO, HMO
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PPO, HMO, DSN
In Network Coverage Type
HMO, PPO
In Network Coverage Type
HMO, EPO PPO, POS
In Network Coverage Type
PPO, POS, EPO, HMO
Offers a qualified health plan from the Health Insurance Marketplace. Call Emblem to learn more.
In Network Coverage Type
PPO, HMO
In Network Coverage Type
PPO
In Network Coverage Type
HMO, EPO
Offers a qualified health plan from the Health Insurance Marketplace. Call Fidelis to learn more.
In Network Coverage Type
EPO, HMO, PPO, POS
Offers a qualified health plan from the Health Insurance Marketplace. Call Healthfirst to learn more.
In Network Coverage Type
HMO
In Network Coverage Type
PPO
In Network Coverage Type
EPO
In Network Coverage Type
EPO
In Network Coverage Type
Federal Government
In Network Coverage Type
PPO, POS, EPO, HMO
In Network Coverage Type
State Government
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Make an Appointment
Contact and Location
Dr. Prince sees patients at three locations.
Looking to see a doctor at a different location? See all MSK locations.
Colleagues
Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.
Clinical Trials
Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.
You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.
Search clinical trialsResearch and Publications
Visit PubMed for a full listing of Dr. Prince’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.
See all on PubMedPatient Reviews
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Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Daniel E. Prince discloses the following relationships and financial interests:
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Modernizing Medicine
Equity
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ROM Technologies, Inc.
Equity
If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.
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This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.
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