The following publications are by fellows for research performaned during their fellowship.
Zarnegar S, Durham BH, Khattar P, Shukla NN, Benayed R, Lacouture ME, Lavi E, Lyden DC, Diamond EL, Dunkel IJ, Abdel-Wahab O. Novel activating BRAF fusion identifies a recurrent alternative mechanism for ERK activation in pediatric Langerhans cell histiocytosis. Pediatr Blood Cancer. 27 Jul 2017, doi: 10.1002/pbc.26699 (PMID: 28748614)
Mathias MD, Ortiz MV, Magnan H, Ambati SR, Slotkin EK, Chou AJ, Walsh MF, Offit K, Moskowitz C, Kentsis A, Wexler LH. A case report of concurrent embryonal rhabdomyosarcoma and diffuse large B-cell lymphoma in an adult without identifiable cancer predisposition. Biomark Res. 8 Feb 2017. eCollection 2017. (PMID: 28194276, PMCID: PMC5299656, DOI: 10.1186/s40364-017-0086-7)
Ortiz MV, Magnan H, Slotkin EK, Ambati SR, Chou AJ, Wexler LH, Meyers PA, Walsh MF, Heaton T, Girardi LN, Wolden SL, Price AP, Kennedy JA, Zehir A, Harneed M, Berger MF, Kentsis A, Shukla N. Intracardiac Low-grade Sarcoma Following Treatment for Ewing Sarcoma. J Pediatr Hematol Oncol. 5 Jan 2017. (PMID: 28060130 PMCID: PMC5498269 [Available on 2018-07-05] DOI: 10.1097/MPH.0000000000000754)
Mathias MD, Ambati SR, Chou AJ, Slotkin EK, Wexler LH, Meyers PA, Magnan H. A single-center experience with undifferentiated embryonal sarcoma of the liver. Pediatr Blood Cancer. Dec 2016. (PMID: 27427850 PMCID: PMC5073002 [Available on 2017-12-01] DOI: 10.1002/pbc.26154)
Kolb M, Offer K, Jin Z, Kahn J, Bhatia M, Kung AL, Garvin JH, George D, Satwani P. Risk Factors for Subtherapeutic Tacrolimus Levels after Conversion from Continuous Intravenous Infusion to Oral in Children after Allogeneic Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. May 2016; 22(5):957-61. doi: 10.1016/j.bbmt.2016.02.005. Epub 2016 Feb 13. (PMID: 26880117)
Offer K, Kolb M, Jin Z, Bhatia M, Kung AL, George D, Garvin JH, Robinson C, Sosna J, Karamehmet E, Satwani P. Efficacy of tacrolimus/mycophenolate mofetil as acute graft-versus-host disease prophylaxis and the impact of subtherapeutic tacrolimus levels in children after matched sibling donor allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant. Mar 2015; 21(3):496-502. doi: 10.1016/j.bbmt.2014.11.679. Epub 2014 Dec 20. (PMID: 25536217)
Ortiz MV, Kobos R, Walsh M, Slotkin EK, Roberts S, Berger MF, Hameed M, Solit D, Ladanyi M, Shukla N, Kentsis A. Integrating Genomics Into Clinical Pediatric Oncology Using the Molecular Tumor Board at the Memorial Sloan Kettering Cancer Center. Pediatr Blood Cancer. 15 Apr 2016. [Epub ahead of print]
Ortiz MV, Dunkel IJ. Retinoblastoma. J Child Neurol. 2016 Feb;31(2):227-36.
Keyes A*, Mathias MD*, Boulad F, Lee YJ, Marchetti MA, Scaradavou A, Spitzer B, Papanicolaou GA, Wieczorek I, Busam KJ. “Cutaneous involvement of disseminated adenovirus infection in an allogeneic stem cell transplant recipient” Br. J. Dermatology. 2015 Dec; Epub Ahead of print.
Suzuki M, Cheung NK. Disialoganglioside GD2 as a therapeutic target for human diseases. Expert Opinion on Therapeutic Targets: (in press), 2014
Dobrenkov K, Cheung NK. GD2-Targeted Immunotherapy and Radioimmunotherapy. Seminars in Oncology, 2014 October, 41, Issue 5, P 589–612.
Giulino L, Mathew S, Ballon G, Chadburn A, Barouk S, Antonicelli G, Leoncini L, Liu YF, Gogineni S, Tam W, Cesarman E. A20 (TNFAIP3) genetic alterations in EBV-associated AIDS-related lymphoma. Blood. 2011 May 5;117(18):4852-4.
Giulino L, Guinan EC, Gillio AP, Drachtman J, Teruya-Feldstein J, Boulad F. Sweet Syndrome in Patients with Fanconi Anemia: Association with Extracutaneous Manifestations and Progression of Hematologic Disease. British Journal of Haematology. 2011 Jul;154(2):278-81.
Kaplan RN, Rafii S, Lyden D. Preparing the “soil”: the premetastatic niche. Cancer Res. 2006 Dec 1;66(23):11089-93
Karajannis MA, Lyden DC, Khakoo Y, Dunkel IJ. Treatment-related Myelodysplastic Syndrome After Chemotherapy for Childhood Low-grade Astrocytoma. J Pediatr Hematol Oncol. 2006 Oct;28(10):700.
Gilheeney SW, Lyden DC, Sgouros S, Antunes N, Gerald W, Kramer K, Lis E, Meyers P, Rosen N, Thaler HT, Trippett T, Wexler L, Dunkel IJ. A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignancies. Pediatr Blood Cancer. 2006 Sep 13
Shukla NN, Trippett TM. Non-Hodgkin’s lymphoma in children and adolescents. Curr Oncol Rep. 2006 Sep;8(5):387-94.
Karajannis MA, Vincent L, Direnzo R, Shmelkov SV, Zhang F, Feldman EJ, Bohlen P, Zhu Z, Sun H, Kussie P, Rafii S. Activation of FGFR1beta signaling pathway promotes survival, migration and resistance to chemotherapy in acute myeloid leukemia cells. Leukemia. 2006 Jun;20(6):979-86.
Zacharoulis S, Abramson DH, Dunkel IJ. More aggressive bone marrow screening in retinoblastoma patients is not indicated: The Memorial Sloan Kettering Cancer Center experience. Pediatr Blood Cancer. 2006 Jan;46(1):56-61
Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, Port ER, Ruggero D, Shmelkov SV, Jensen KK, Rafii S, Lyden D. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005; 438: 820-827
Goldberg SM, Bartido SM, Gardner JP, Guevara-Patino JA, Montgomery SC, Perales MA, Maughan MF, Dempsey J, Donovan GP, Olson WC, Houghton AN, Wolchok JD. Comparison of two cancer vaccines targeting tyrosinase: plasmid DNA and recombinant alphavirus replicon particles. Clin Cancer Res. 2005 Nov 15;11(22):8114-21
Waldman E, Lu SX, Hubbard VM, Kochman AA, Eng JM, Terwey TH, Muriglan SJ, Kim TD, Heller G, Murphy GF, Liu C, Alpdogan O, van den Brink MR. Absence of the beta-7 integrin results in less graft-versus-host disease due to decreased homing of alloreactive T cells to intestine. Blood. 2005 Nov 15
Chou AJ, Merola PR, Wexler LH, Gorlick RG, Vyas YM, Healey JH, Laquaglia MP, Huvos AG, Meyers PA. Treatment of osteosarcoma at first recurrence after contemporary therapy. Cancer. 2005 Nov 15;104(10):2214-21
Solit DB, Garraway LA, Pratilas CA, Sawai A, Getz G, Basso A, Ye Q, Lobo JM, She Y, Osman I, Golub TR, Sebolt-Leopold J, Sellers WR, Rosen N. BRAF mutation predicts sensitivity to MEK inhibition. Nature. 2005 Nov 6
Bussel JB, Zacharoulis S, Kramer K, McFarland JG, Pauliny J, Kaplan C. Clinical and diagnostic comparison of neonatal alloimmune thrombocytopenia to non-immune cases of thrombocytopenia. Pediatr Blood Cancer. 2005 Aug;45(2):176-83
Zelcer S, Kellick M, Wexler LH, Shi W, Sankaran M, Lo S, Healey J, Huvos AG, Meyers PA, Gorlick R. Methotrexate levels and outcome in osteosarcoma. Pediatr Blood Cancer. 2005 Jun 15;44(7):638-42
Vidal A, Zacharoulis S, Guo W, Shaffer D, Giancotti F, Bramley AH, de la Hoz C, Jensen KK, Kato D, MacDonald DD, Knowles J, Yeh N, Frohman LA, Rafii S, Lyden D, Koff A. p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6890-5
Vincent L, Jin DK, Karajannis MA, Shido K, Hooper AT, Rashbaum WK, Pytowski B, Wu Y, Hicklin DJ, Zhu Z, Bohlen P, Niesvizky R, Rafii S. Fetal stromal-dependent paracrine and intracrine vascular endothelial growth factor-a/vascular endothelial growth factor receptor-1 signaling promotes proliferation and motility of human primary myeloma cells. Cancer Res. 2005 Apr 15;65(8):3185-92
Zelcer S, Kolesnikov Y, Kovalyshyn I, Pasternak DA, Pasternak GW. Selective potentiation of opioid analgesia by nonsteroidal anti-inflammatory drugs. Brain Res. 2005 Apr 8;1040(1-2):151-6
Trivedi D, Williams RY, O’Reilly RJ, Koehne G. Generation of CMV-specific T lymphocytes using protein-spanning pools of pp65-derived overlapping pentadecapeptides for adoptive immunotherapy. Blood. 2005 Apr 1;105(7):2793-801
Yurasov S, Wardemann H, Hammersen J, Tsuiji M, Meffre E, Pascual V, Nussenzweig MC. Defective B cell tolerance checkpoints in systemic lupus erythematosus. J Exp Med. 2005 Mar 7;201(5):703-11
Yang ZQ, Geng X, Solit D, Pratilas CA, Rosen N, Danishefsky SJ. New efficient synthesis of resorcinylic macrolides via ynolides: establishment of cycloproparadicicol as synthetically feasible preclinical anticancer agent based on Hsp90 as the target. J Am Chem Soc. 2004 Jun 30;126(25):7881-9
Cheung NK, Modak S, Lin Y, Guo H, Zanzonico P, Chung J, Zuo Y, Sanderson J, Wilbert S, Theodore LJ, Axworthy DB, Larson SM. Single-chain Fv-streptavidin substantially improved therapeutic index in multistep targeting directed at disialoganglioside GD2. J Nucl Med. 2004 May;45(5):867-77
Su WT, Chewning J, Abramson S, Rosen N, Gholizadeh M, Healey J, Meyers P, La Quaglia MP. Surgical management and outcome of osteosarcoma patients with unilateral pulmonary metastases. J Pediatr Surg. 2004 Mar;39(3):418-23
Kaplan RN, Bussel JB. Differential diagnosis and management of thrombocytopenia in childhood. Pediatr Clin North Am. 2004 Aug;51(4):1109-40
Petrovic A, Alpdogan O, Willis LM, Eng JM, Greenberg AS, Kappel BJ, Liu C, Murphy GJ, Heller G, van den Brink MR. LPAM (alpha 4 beta 7 integrin) is an important homing integrin on alloreactive T cells in the development of intestinal graft-versus-host disease. Blood. 2004 Feb 15;103(4):1542-7
Heller KN, Teruya-Feldstein J, La Quaglia MP, Wexler LH. Primary follicular lymphoma of the testis: excellent outcome following surgical resection without adjuvant chemotherapy. J Pediatr Hematol Oncol. 2004 Feb;26(2):104-7
Wardemann H, Yurasov S, Schaefer A, Young JW, Meffre E, Nussenzweig MC. Predominant autoantibody production by early human B cell precursors. Science. 2003 Sep 5;301(5638):1374-7
Trivedi DH, Bussel JB. 21. Immunohematologic disorders. J Allergy Clin Immunol. 2003 Feb;111(2 Suppl):S669-76
Perales MA, Fantuzzi G, Goldberg SM, Turk MJ, Mortazavi F, Busam K, Houghton AN, Dinarello CA, Wolchok JD. GM-CSF DNA induces specific patterns of cytokines and chemokines in the skin: implications for DNA vaccines. Cytokines Cell Mol Ther. 2002;7(3):125-33
Turk MJ, Wolchok JD, Guevara-Patino JA, Goldberg SM, Houghton AN. Multiple pathways to tumor immunity and concomitant autoimmunity. Immunol Rev. 2002 Oct;188:122-35
Trcka J, Moroi Y, Clynes RA, Goldberg SM, Bergtold A, Perales MA, Ma M, Ferrone CR, Carroll MC, Ravetch JV, Houghton AN. Redundant and alternative roles for activating Fc receptors and complement in an antibody-dependent model of autoimmune vitiligo. Immunity. 2002 Jun;16(6):861-8
Heath JA, Kurland G, Spray TL, Kernan NA, Small TN, Brochstein JA, Gillio AP, Boklan J, O’Reilly RJ, Boulad F. Lung transplantation after allogeneic marrow transplantation in pediatric patients: the Memorial Sloan Kettering experience. Transplantation. 2001 Dec 27;72(12):1986-90