Uterine Leiomyosarcoma Nomogram: Overall Survival Probability Following Surgery

In the U.S.

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Our uterine leiomyosarcoma nomogram is a tool designed to predict the likelihood of survival at five years after undergoing surgery to remove the uterine leiomyosarcoma, a type of uterine cancer. It is not appropriate for patients who have not had surgical treatment for uterine leiomyosarcoma.

Results produced by this tool are based on data from patients treated at MSK, a large research institution with surgeons who perform a high volume of uterine cancer procedures. This tool has been externally validated using data from patients treated at large, international sarcoma centers (see Supporting Publications). All results must be understood in the context of each patient’s specific treatment plan. Patients and caregivers using this tool should discuss the result with the patient’s physician.

To gather the information required to use this nomogram, use our worksheet.

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How old were you when you were diagnosed with uterine leiomyosarcoma? years (20 to 80)

What was the size of the primary uterine leiomyosarcoma tumor? cm (0 to 28)

What was the grade of the tumor?

What is grade?: Tumor grade refers to the extent of abnormality of the cells when viewed under the microscope. “Low-grade” cells look normal and grow slowly; “high-grade” cells look abnormal and grow quickly.

Was there cervical involvement at the time of your surgery?

Yes

What is cervical involvement?: Cervical involvement refers to cancer that has spread to the cervical portion of the uterus, which is the lower, narrow end (the “neck”) of the uterus.

Were there loco-regional metastases at the time of your surgery?

Yes

Note: Loco-regional metastases were present if, at the time of surgery, the leiomyosarcoma was found in the structures near the uterus, including the bladder, nearby bowel, nearby lymph nodes, parametria, ovaries, or fallopian tubes.

Were there distant metastases either before or soon after your surgery?

Yes

Note: Distant metastases were present if imaging studies done either before or soon after surgery showed that the leiomyosarcoma had spread to distant areas, such as the lung, liver, or bone.

What was the mitotic index? mitoses/10 HPF (1 to 245)

Note: This is expressed as the number of mitotic figures per 10 high-powered fields (HPF) seen under the microscope. If the pathology report gives a range (such as 8 to 20 mitoses/10 HPF), use the higher number (20 mitoses/10 HPF).