Hospital Research Teams

Advanced Computing and Oncology Lab

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Overview

Tafadzwa Lawrence Chaunzwa
Lab Head

The Advanced Computing and Oncology Lab is dedicated to advancing the intersection of clinical oncology and computational sciences, with a primary focus on lung cancer and related thoracic malignancies. Our program bridges scientific novelty and clinical relevance, positioning efforts along a continuum to maximize both the advancement of AI methods and improvement in patient outcomes.

Publications

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA. Abbosh C, Frankell AM, Harrison T, Kisistok J, Garnett A, Johnson L, Veeriah S, Moreau M, Chesh A, Chaunzwa TL, Weiss J, Schroeder MR, Ward S, Grigoriadis K, Shahpurwalla A, Litchfield K, Puttick C, Biswas D, Karasaki T, Black JRM, Martínez-Ruiz C, Bakir MA, Pich O, Watkins TBK, Lim EL, Huebner A, Moore DA, Godin-Heymann N, L’Hernault A, Bye H, Odell A, Roberts P, Gomes F, Patel AJ, Manzano E, Hiley CT, Carey N, Riley J, Cook DE, Hodgson D, Stetson D, Barrett JC, Kortlever RM, Evan GI, Hackshaw A, Daber RD, Shaw JA, Aerts HJWL, Licon A, Stahl J, Jamal-Hanjani M; TRACERx Consortium; Birkbak NJ, McGranahan N, Swanton C. Nature. 2023 Apr;616(7957):553-562. doi: 10.1038/s41586-023-05776-4. Epub 2023 Apr 13.

Foundation model for cancer imaging biomarkers.Pai S, Bontempi D, Hadzic I, Prudente V, Sokač M, Chaunzwa TL, Bernatz S, Hosny A, Mak RH, Birkbak NJ, Aerts HJWL. Nat Mach Intell. 2024;6(3):354-367. doi: 10.1038/s42256-024-00807-9. Epub 2024 Mar 15.

Body Composition in Advanced Non-Small Cell Lung Cancer Treated With Immunotherapy.Chaunzwa TL, Qian JM, Li Q, Ricciuti B, Nuernberg L, Johnson JW, Weiss J, Zhang Z, MacKay J, Kagiampakis I, Bikiel D, Di Federico A, Alessi JV, Mak RH, Jacob E, Awad MM, Aerts HJWL. JAMA Oncol. 2024 Jun 1;10(6):773-783. doi: 10.1001/jamaoncol.2024.1120.

Large language models to identify social determinants of health in electronic health records.Guevara M, Chen S, Thomas S, Chaunzwa TL, Franco I, Kann BH, Moningi S, Qian JM, Goldstein M, Harper S, Aerts HJWL, Catalano PJ, Savova GK, Mak RH, Bitterman DS. NPJ Digit Med. 2024 Jan 11;7(1):6. doi: 10.1038/s41746-023-00970-0.

Clinical Informatics Approaches to Understand and Address Cancer Disparities.Chaunzwa TL, Del Rey MQ, Bitterman DS. Yearb Med Inform. 2022 Aug;31(1):121-130. doi: 10.1055/s-0042-1742511. Epub 2022 Dec 4.

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People

Tafadzwa Lawrence Chaunzwa

Lab Head

Members

Alexander Kim

University of Illinois Student

Ryan Kim

Student

Victor Lee

Yale Radiation Oncology Resident

Innocent Maturure

The College of St. Scholastica

Jason McFadden

Yale Medical Student

Jeff Meng

Postdoctoral Fellow, Computational Oncology; Resident Physician, Radiation Oncology

Ricardo Reyes

Harvard Medical Student

Elaine Yang

Yale Medical Student

Affiliations

Achievements

  • James D. Cox Research Award, Radiation Oncology Institute (2022)
  • Young Investigator Award, American Society of Clinical Oncology/Conquer Cancer Foundation (2023)

Open Positions

To learn more about available postdoctoral opportunities, please visit our Career Center

Career Opportunities

We are looking for Post-Doctoral Fellows, Graduate Research Assistants, Data Analysts, and Student Researchers.

Apply now