Research Labs

Molecular biologist John Maciejowski studies the causes of complex chromosome rearrangements and the patterns of hypermutation that shape cancer genomes.

Molecular and cell biologist Christine Mayr studies how 3′UTRs regulate protein functions and how mRNAs contribute to cytoplasmic organization.

Physician-scientist Ingo Mellinghoff studies signal transduction alterations in primary brain tumors.

Luc Morris is a physician-scientist whose laboratory studies how tumor genetics influence the development of cancer, escape from immune surveillance, and immunotherapy outcomes in cancers of the head and neck and other sites.

Computational biologist Quaid Morris uses artificial intelligence techniques and develops machine learning algorithms to study gene regulation, cancer evolution, clinical informatics, and other topics in systems biology.

Cell biologist Philipp Niethammer investigates tissue damage responses with advanced imaging approaches in zebrafish.

Systems biologist Thomas Norman develops new computational and functional genomics approaches for studying how genes interact to realize complex phenotypes.

Cancer geneticist Kenneth Offit focuses on gene characterization; genetic and epidemiologic studies of cancer-predisposing alleles; and the therapeutic, prognostic, and psychosocial translation of these findings.

Led by Dr. Irene Orlow, the Lab participates in self-initiated research and supports investigations from the Population Sciences & Clinical Research programs that involve handling and testing human specimens. For additional information on current research, publications, and presentations by the Lab and more, scroll down and click on the ‘View Lab Overview’ or ‘Current Projects’ links.

The Pavletich laboratory studies the structural biology of pathways that control cell growth and maintain the integrity of the genome.