Memorial Hospital Research Laboratories
The Prasad Adusumilli Lab
Research
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Research led by Prasad S. Adusumilli focuses on investigation of the tumor immune microenvironment and the development of T-cell‒mediated immunotherapy for thoracic malignancies and pleural-based diseases. His team has championed regional immunotherapy delivery strategies, resulting in translation of mesothelin-targeted CAR T-cell immunotherapy for malignant pleural mesothelioma, lung, and breast cancers.
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Cover Image from J Clin Invest Aug 1 2016. Cherkassky L, Morello A, Villena-Vargas J, Feng Y, Dimitrov DS, Jones DR, Sadelain M, Adusumilli PS. Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition. J Clin Invest. 2016;126(8):3130-44
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Cover Image from J Clin Invest Aug 1 2016. Cherkassky L, Morello A, Villena-Vargas J, Feng Y, Dimitrov DS, Jones DR, Sadelain M, Adusumilli PS. Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition. J Clin Invest. 2016;126(8):3130-44.
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Cover Image from J Thoracic Oncology Jan 2022. Gross DJ, Chintala NK, Vaghjiani RG, Grosser R, Tan KS, Li X, Choe J, Li Y, Aly RG, Emoto K, Hua Z, Dux J, Cheema W, Bott MJ, Travis WD, Isbell JM, Li BT, Jones DR, Adusumilli PS. Tumor and Tumor-Associated Macrophage PD-L1 Expression is Associated with Adjuvant Chemotherapy Benefit in Lung Adenocarcinoma. J Thorac Oncol. 2022;17(1):89-102.
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Cover Image from Cancer Discovery Nov 2021. Adusumilli PS, Zauderer MG, Rivière I, Solomon SB, Rusch VW, O’Cearbhaill RE, Zhu A, Cheema W, Chintala NK, Halton H, Pineda J, Perez-Johnston R, Tan KS, Daly B, Araujo Filho JA, Ngai D, McGee E, Vincent A, Diamonte C, Sauter JL, Modi S, SikderD, Senechal B, Wang X, Travis WD, Gönen M, Rudin CM, Brentjens RJ, Jones RJ, Sadelain M. A phase I trial of regional mesothelin-targeted CAR T-cell therapy in patients with malignant pleural disease, in combination with the anti-PD-1 agent pembrolizumab. Cancer Discov. 2021;11(11):2748-2763.
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Cover Image from J Thoracic Oncology Jan 2018. Kiesgen S, Chicaybam L, Chintala NK, Adusumilli PS*. Chimeric antigen receptor (CAR) T-cell therapy for thoracic malignancies. J Thorac Oncol. 2018;13(1):16-26.
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Cover Image from Mol Ther Oncolytics – Vol 4, Mar 17, 2017.
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Image from Science Sept 2016. Couzin-Frankel J. (2016, September 2). Second chapter. Science. 353(6303):983-5.5.
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Cover Image from Cancer Immunology Research Oct 2023. Quach HT, Skovgard MS, Villena-Vargas J, Bellis RY, Chintala NK, Amador-Molina A, Bai Y, Banerjee S, Saini J, Xiong Y, Vista WR, Byun AJ, De Biasi A, Zeltsman M, Mayor M, Morello A, Mittal V, Gomez DR, Rimner A, Jones DR, Adusumilli PS. Tumor-Targeted Nonablative Radiation Promotes Solid Tumor CAR T-cell Therapy Efficacy. Cancer Immunol Res. 2023 Oct 4;11(10):1314-1331. doi: 10.1158/2326-6066.CIR-22-0840. PMID: 37540803; PMCID: PMC10592183.
Featured News
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Publications Highlights
People
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Prasad S. Adusumilli, MD
Professor and Deputy Chief, Thoracic Service; Vice Chair for Translational Research, Dept. of Surgery; Co-Director, MSK Mesothelioma Program; Min H. and Yu-Fan C. Kao Chair in Thoracic Cancers
- Physician-scientist Prasad S. Adusumilli studies tumor immunology and the development of T-cell‒mediated immunotherapy for thoracic malignancies and pleural-based diseases.
- View physician profile
- Physician profile
Members
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- PhD, National Autonomous University of Mexico, Mexico City, Mexico
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- MS, Northeastern University, Boston, MA
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- MS, Biomedical Engineering, Stony Brook University, Stony Brook, NY
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- BS, Biology, St. John’s University, New York City, NY
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- BA, Biology, Brooklyn College, Brooklyn, NY
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- MD, Ross University School of Medicine, Dominica/New York, NY
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- MS, Biotechnology and Entrepreneurship, Polytechnic Institute of NYU, Brooklyn, NY
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- MD, Jacobs School of Medicine, Buffalo, NY
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- PhD, Tokyo Medical and Dental University, Tokyo, Japan
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- PhD, Microbiology and Biochemical Pharmacy, Shandong University, Jinan, P.R. China
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- MS, Oncology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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- MD, PhD, Seoul National University Bundang Hospital, Seoul, Republic of Korea
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- PhD, MS, Ohio University, Athens, OH
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- Ph.D., University of Alabama at Birmingham, Birmingham, AL
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- BS, Biochemistry, University of California, Santa Barbara, CA
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- MD, PhD, Tampere University, Tampere, Finland, University of Helsinki, Helsinki, Finland
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- MHA, Stony Brook University, Stony Brook, NY
- BA, Biology, Smith College, Northampton, MA
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- PhD, University of Bern, Bern, Switzerland
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- BS, Biology, CUNY York College, Jamaica, NY
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- PhD, University of Orleans, Orleans, France
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- BS, Stony Brook University, Stony Brook, NY
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- MD, University of Algiers, Algeria
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Research Associate
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Bioinformatics Technician
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Research Assistant
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Senior Research Technician
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Research Fellow
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Clinical Research Coordinator
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Research Project Manager
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Senior Research Assistant
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Research Fellow
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Research Fellow
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Senior Research Scientist
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Research Technician
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Visiting Investigator
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Research Fellow
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Research Fellow
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Research Technician
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Research Fellow
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Project Manager
Research Technician
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Research Fellow
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Clinical Research Associate
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Research Fellow
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Senior Research Assistant
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Research Fellow
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- MD, University of South California, Los Angeles, CA
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- DO, A.T. Still University, Kirksville, MO
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- PhD, Tehran University, Iran & University of Calgary, Canada
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- BS, Molecular Biology, St. Lawrence University, Canton, NY
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- MSc, Biomedicine, National Autonomous University of Mexico, Mexico City, Mexico
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- Biotechnology and Biotherapy, Paris Diderot University, Paris, France
- MS, Cardiovascular Physiology, Paris Descartes University, Paris, France
- MS, Biology Engineering, The University of Science and Technology, Algiers, Algeria
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- PhD, Graduate Institute of Pathology, National Taiwan University College of Medicine, Taipei, Taiwan
- MD, National Taiwan University College of Medicine, Taipei, Taiwan
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- Dr. rer. nat. (Ph.D. equivalent), Biology, Heidelberg University, Heidelberg, Germany
- MS, Biotechnology, RWTH Aachen, Aachen, Germany
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- PharmD, Pharmaceutic Innovation and Research, University of Nantes, Nantes, France
- PhD, Biology and Health, University of Nantes, Nantes, France
- MS, Development and Control of Health Products, University of Nantes, Nantes, France
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- PhD, Molecular Biology, Department of Biochemistry and Molecular Biology, University of Santiago de Compostela, Santiago, Spain
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- PhD, Biotechnology, Kyoto Institute of Technology, Kyoto, Japan
- MS, Applied Biology, Kyoto Institute of Technology, Kyoto, Japan
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- BS, Biology, SUNY Old Westbury, Jericho, New York
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- BS, York College, New York, NY
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- MD, Tulane University School of Medicine, New Orleans, LA
- MS, University of Cincinnati, Cincinnati, OH
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- PhD, Pathology and Pathophysiology, Fudan University, Shanghai, China
- MS, Immunology, Guangzhou Medical College, Guangzhou, China
- MD, North China Coal Medical College, Tangshan, China
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- BS, Biology, Cornell University, Ithaca, New York
Lab Alumni
Visiting Research Scholar
Research Fellow
Research Fellow
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Interventional Pulmonologist
Research Study Assistant II
Research Fellow
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Research Fellow
Research Fellow
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Research Fellow
Visiting Investigator
Visiting Investigator
Research Fellow
Research Fellow
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Research Fellow
Research Fellow
Research Technician
Research Fellow
Research Scholar
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Research Fellow
Research Fellow
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Research Associate
Research Fellow
Research Fellow
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Project Manager
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Research Fellow
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Research Fellow
Research Study Assistant
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Senior Research Technician

Senior Research Scientist
Research Fellow

Visiting Investigator
Research Fellow
Senior Research Scientist
Visiting Research Scholar
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Research Fellow

Project Portfolio Manager
Visiting Research Scholar
Research Fellow

Visiting Investigator

Research Fellow

Senior Research Scientist
Visiting Research Scholar
Research Fellow
Research Technician

Predoctoral Fellow

Senior Research Scientist
Senior Research Technician
Research Scholar
Research Fellow
Research Fellow
Visiting Research Scholar

Research Associate
Research Assistant
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Clinical Research Coordinator

Research Technician
Research Fellow
Research Fellow

Research Fellow
Research Fellow
Research Fellow
Research Fellow
Research Fellow
Research Fellow
Research Fellow
Research Technician

Senior Research Scientist
Visiting Research Scholar
Research Scholar
Visiting Research Scholar
Research Fellow
Visiting Research Scholar

Research Project Manager
Lab Affiliations
Achievements
- The Rodman E. Sheed and Thomas G. Sheed Awarded to Dr. Adusumilli
- Current NCI Awards Received: R01 CA235667; R01 CA236615; R01 CA292664; UG3/UH3 CA29024
- Current DoD Award Received: CA200437
- Published in the Journal Cover Pages listed below: J Clin Invest Aug 2016; Science Sept 2016; J Thorac Oncol Jan 2018; Cancer Discov Nov 2021; J Thorac Oncol Jan 2022; Cancer Immunol Res Oct 2023
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs