A systematic review and meta-analysis of nonrelapse mortality after CAR T cell therapy. Cordas Dos Santos DM, Tix T, Shouval R, Gafter-Gvili A, Alberge JB, Cliff ERS, Theurich S, von Bergwelt-Baildon M, Ghobrial IM, Subklewe M, Perales MA, Rejeski K.Nat Med. 2024 Jul 8. doi: 10.1038/s41591-024-03084-6. Online ahead of print.PMID: 38977912

CD19-directed CART Therapy for T cell/Histiocyte Rich Large B-cell Lymphoma. Pophali PA, Fein JA, Ahn KW, Allbee-Johnson M, Ahmed N, Awan FT, Farhan S, Grover NS, Hilal T, Iqbal M, Maakaron J, Modi D, Nasrollahi E, Schachter L, Sauter CS, Hamadani M, Herrera AF, Shouval R, Shadman M.Blood Adv. 2024 Jul 10:bloodadvances.2024013863. doi: 10.1182/bloodadvances.2024013863. Online ahead of print.PMID: 38985302

Subsequent Malignancies after CD19-Targeted Chimeric Antigen Receptor T cells in Patients with Lymphoma. Lorenc R*, Shouval R*, Flynn JR, Devlin SM, Saldia A, De Abia AL, De Lapuerta MC, Tomas AA, Cassanello G, Leslie LA, Rejeski K, Lin RJ, Scordo M, Shah GL, Palomba ML, Salles G, Park J, Giralt SA, Perales MA, Ip A, Dahi PB.Transplant Cell Ther. 2024 Jul 5:S2666-6367(24)00491-3. doi: 10.1016/j.jtct.2024.06.027. Online ahead of print.PMID: 38972512 *Equal contribution

Conditioning Regimens are Associated with Distinct Patterns of Microbiota Injury in Allogeneic Hematopoietic Cell Transplantation. Shouval R, Waters NR, Gomes ALC, Zuanelli Brambilla C, Fei T, Devlin SM, Nguyen CL, Markey KA, Dai A, Slingerland JB, Clurman AG, Fontana E, Amoretti LA, Wright RJ, Hohl TM, Taur Y, Sung AD, Weber D, Hashimoto D, Teshima T, Chao NJ, Holler E, Scordo M, Giralt SA, Perales MA, Peled JU, van den Brink MRM.Clin Cancer Res. 2023 Jan 4;29(1):165-173. doi: 10.1158/1078-0432.CCR-22-1254.

Atrial arrhythmias following CAR-chimeric antigen receptor T-cell therapy: Incidence, risk factors and biomarker profile. Shouval R, Goldman A, Flynn JR, El-Moghraby A, Rehman M, Devlin SM, Corona M, Landego I, Lin RJ, Scordo M, Raj SS, Giralt SA, Palomba ML, Dahi PB, Walji M, Salles G, Nath K, Geyer MB, Park JH, Fein JA, Kosmidou I, Shah GL, Liu JE, Perales MA, Mahmood SS.Br J Haematol. 2024 May 12. doi: 10.1111/bjh.19497. Online ahead of print.PMID: 38735683

Conventional and novel [18F]FDG PET/CT features as predictors of CAR-T cell therapy outcome in large B-cell lymphoma. Leithner D, Flynn JR, Devlin SM, Mauguen A, Fei T, Zeng S, Zheng J, Imber BS, Hubbeling H, Mayerhoefer ME, Bedmutha A, Luttwak E, Corona M, Dahi PB, Luna de Abia A, Landego I, Lin RJ, Palomba ML, Scordo M, Park JH, Tomas AA, Salles G, Lafontaine D, Michaud L, Shah GL, Perales MA, Shouval R*, Schöder H*. J Hematol Oncol. 2024 Apr 23;17(1):21. doi: 10.1186/s13045-024-01540-x. PMID: 38649972 Free PMC article. * Equal contribution

T-Cell Malignant Neoplasms After Chimeric Antigen Receptor T-Cell Therapy. Storgard R, Rejeski K, Perales MA, Goldman A, Shouval R. JAMA Oncol. 2024 Apr 18. doi: 10.1001/jamaoncol.2024.0662. Online ahead of print. PMID: 38635228

Development and validation of an automated computational approach to grade immune effector cell-associated hematotoxicity. Liang EC* Rejeski K*, Fei T, Albittar A, Huang JJ, Portuguese AJ, Wu Q, Raj S, Subklewe M, Shouval R*, Gauthier J*. Bone Marrow Transplant. 2024 Apr 16. doi: 10.1038/s41409-024-02278-3. Online ahead of print. PMID: 38627450 * Equal contribution

Fecal microbiota transplantation in capsules for the treatment of steroid refractory and steroid dependent acute graft vs. host disease: a pilot study. Youngster I, Eshel A, Geva M, Danylesko I, Henig I, Zuckerman T, Fried S, Yerushalmi R, Shem-Tov N, Fein JA, Bomze D, Shimoni A, Koren O, Shouval R*., Nagler A.* Bone Marrow Transplant. 2024 Mar;59(3):409-416. doi: 10.1038/s41409-024-02198-2. Epub 2024 Jan 11. PMID: 38212672 * Equal contribution

The sum of the parts: what we can and cannot learn from comorbidity scores in allogeneic transplantation. Shouval R, Fein JA. Hematology Am Soc Hematol Educ Program. 2023 Dec 8;2023(1):715-722. doi: 10.1182/hematology.2023000458. PMID: 38066892 Review.

Systematic evaluation of donor-KIR/recipient-HLA interactions in HLA-matched hematopoietic cell transplantation for AML. Fein JA*, Shouval R*, Krieger E, Spellman SR, Wang T, Baldauf H, Fleischhauer K, Kröger N, Horowitz M, Maiers M, Miller JS, Mohty M, Nagler A, Weisdorf D, Malmberg KJ, Toor AA, Schetelig J, Romee R, Koreth J. Blood Adv. 2024 Feb 13;8(3):581-590. doi: 10.1182/bloodadvances.2023011622. PMID: 38052043 Free PMC article. * Equal contribution

The Simplified Comorbidity Index predicts non-relapse mortality in reduced-intensity conditioning allogeneic haematopoietic cell transplantation. Elias S, Brown S, Devlin SM, Barker JN, Cho C, Chung DJ, Dahi PB, Giralt S, Gyurkocza B, Jakubowski AA, Lahoud OB, Landau H, Lin RJ, Papadopoulos EB, Politikos I, Ponce DM, Scordo M, Shaffer BC, Shah GL, Tamari R, Young JW, Perales MA, Shouval R. Br J Haematol. 2023 Dec;203(5):840-851. doi: 10.1111/bjh.19055. Epub 2023 Aug 24. PMID: 37614192

High-resolution analyses of associations between medications, microbiome, and mortality in cancer patients.

Nguyen CL, Markey KA, Miltiadous O, Dai A, Waters N, Sadeghi K, Fei T, Shouval R, Taylor BP, Liao C, Slingerland JB, Slingerland AE, Clurman AG, Maloy MA, Bohannon L, Giardina PA, Brereton DG, Armijo GK, Fontana E, Gradissimo A, Gyurkocza B, Sung AD, Chao NJ, Devlin SM, Taur Y, Giralt SA, Perales MA, Xavier JB, Pamer EG, Peled JU, Gomes ALC, van den Brink MRM. Cell. 2023 Jun 8;186(12):2705-2718.e17. doi: 10.1016/j.cell.2023.05.007. Epub 2023 Jun 8. PMID: 37295406

Progressive multifocal leukoencephalopathy in patients treated with chimeric antigen receptor T cells. Goldman A, Raschi E, Chapman J, Santomasso BD, Pasquini MC, Perales MA, Shouval R. Blood. 2023 Feb 9;141(6):673-677. doi: 10.1182/blood.2022017386. PMID: 36332168 Free PMC article.

Outcomes of first therapy after CD19-CAR-T treatment failure in large B-cell lymphoma.

Alarcon Tomas A, Fein JA, Fried S, Flynn JR, Devlin SM, Fingrut WB, Anagnostou T, Alperovich A, Shah N, Fraint E, Lin RJ, Scordo M, Batlevi CL, Besser MJ, Dahi PB, Danylesko I, Giralt S, Imber BS, Jacoby E, Kedmi M, Nagler A, Palomba ML, Roshal M, Salles GA, Sauter C, Shem-Tov N, Shimoni A, Yahalom J, Yerushalmi R, Shah GL, Avigdor A, Perales MA, Shouval R. Leukemia. 2023 Jan;37(1):154-163. doi: 10.1038/s41375-022-01739-2. Epub 2022 Nov 5. PMID: 36335261 Free PMC article.

Impact of TP53 Genomic Alterations in Large B-Cell Lymphoma Treated With CD19-Chimeric Antigen Receptor T-Cell Therapy.

Shouval R*, Alarcon Tomas A*, Fein JA, Flynn JR, Markovits E, Mayer S, Olaide Afuye A, Alperovich A, Anagnostou T, Besser MJ, Batlevi CL, Dahi PB, Devlin SM, Fingrut WB, Giralt SA, Lin RJ, Markel G, Salles G, Sauter CS, Scordo M, Shah GL, Shah N, Scherz-Shouval R, van den Brink M, Perales MA, Palomba ML. J Clin Oncol. 2022 Feb 1;40(4):369-381. doi: 10.1200/JCO.21.02143. Epub 2021 Dec 3. PMID: 34860572 Free PMC article. * Equal contribution

Adverse Cardiovascular and Pulmonary Events Associated With Chimeric Antigen Receptor T-Cell Therapy. Goldman A, Maor E, Bomze D, Liu JE, Herrmann J, Fein J, Steingart RM, Mahmood SS, Schaffer WL, Perales MA, Shouval R. J Am Coll Cardiol. 2021 Nov 2;78(18):1800-1813. doi: 10.1016/j.jacc.2021.08.044. PMID: 34711339 Free PMC article.

Origins of bloodstream infections following fecal microbiota transplantation: a strain-level analysis. Eshel A, Sharon I, Nagler A, Bomze D, Danylesko I, Fein JA, Geva M, Henig I, Shimoni A, Zuckerman T, Youngster I, Koren O, Shouval R. Blood Adv. 2022 Jan 25;6(2):568-573. doi: 10.1182/bloodadvances.2021005110. PMID: 34644375 Free PMC article.

The Simplified Comorbidity Index: a new tool for prediction of nonrelapse mortality in allo-HCT.

Shouval R*, Fein JA*, Cho C, Avecilla ST, Ruiz J, Tomas AA, Sanchez-Escamilla M, Flores NC, Yáñez L, Barker JN, Dahi P, Giralt SA, Geyer AI, Gyurkocza B, Jakubowski AA, Lin RJ, O’Reilly RJ, Papadopoulos EB, Politikos I, Ponce DM, Sauter CS, Scordo M, Shaffer B, Shah GL, Sullivan JP, Tamari R, van den Brink MRM, Young JW, Nagler A, Devlin S, Shimoni A, Perales MA. Blood Adv. 2022 Mar 8;6(5):1525-1535. doi: 10.1182/bloodadvances.2021004319. PMID: 34507354 Free PMC article. * Equal contribution

Development and validation of a disease risk stratification system for patients with haematological malignancies: a retrospective cohort study of the European Society for Blood and Marrow Transplantation registry.

Shouval R*, Fein JA*, Labopin M, Cho C, Bazarbachi A, Baron F, Bug G, Ciceri F, Corbacioglu S, Galimard JE, Giebel S, Gilleece MH, Giralt S, Jakubowski A, Montoto S, O’Reilly RJ, Papadopoulos EB, Peric Z, Ruggeri A, Sanz J, Sauter CS, Savani BN, Schmid C, Spyridonidis A, Tamari R, Versluis J, Yakoub-Agha I, Perales MA, Mohty M, Nagler A. Lancet Haematol. 2021 Mar;8(3):e205-e215. doi: 10.1016/S2352-3026(20)30394-X. PMID: 33636142 Free PMC article. * Equal contribution

Machine learning and artificial intelligence in haematology. Shouval R*, Fein JA*, Savani B, Mohty M, Nagler A. Br J Haematol. 2021 Jan;192(2):239-250. doi: 10.1111/bjh.16915. Epub 2020 Jun 30. PMID: 32602593 Review. * Equal contribution

Patterns of salivary microbiota injury and oral mucositis in recipients of allogeneic hematopoietic stem cell transplantation. Shouval R, Eshel A, Dubovski B, Kuperman AA, Danylesko I, Fein JA, Fried S, Geva M, Kouniavski E, Neuman H, Armon-Omer A, Shahien R, Muller E, Noecker C, Borenstein E, Louzoun Y, Nagler A, Koren O. Blood Adv. 2020 Jul 14;4(13):2912-2917. doi: 10.1182/bloodadvances.2020001827. PMID: 32598476 Free PMC article.